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606,025 grants found
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Dutch-Belgium Drosophila meeting
Researchers using Drosophila as their model organism meet and present their current research. Two key note speakers from outsite the Netherlands or Belgium are invited.Drosophila c...
Genetics Retreat
The annual Genetics Retreat has been organised since the 1990s.The upcoming edition takes place on 18 September, in Amsterdam, immediately preceding the two-day 75th edition of the...
Fight Fatigue: A progressive muscle relaxation and walking intervention to reduce fatigue in adults with ESKD
Project SummaryIn this R34 application, we propose to conduct an early phase clinical trial of a mind-body intervention to promote whole person health—specifically, to develop and...
Cross-brain, multi-region interactions in decision formation and decision commitment
Project Summary/Abstract The brain is composed of many densely interconnected regions, in constant communication and interaction with each other; cognition and behavior emerge from...
Development and Validation of a Mouse Model of Intervertebral Disc Degeneration-Induced Low Back Pain to Facilitate Non-Addictive Analgesic Discovery
PROJECT SUMMARY / ABSTRACT Low back pain (LBP) is a leading cause of disability worldwide with an estimated 40% of LBP attributed to degenerating intervertebral discs (IVD), freque...
Molecular Mechanism of Folding of Nsp12 and Assembly of the SARS-CoV-2 RNA Polymerase Complex by the Cytosolic Chaperonin CCT
PROJECT SUMMARY The COVID-19 pandemic created the greatest infectious threat to global health in 100-years, and monumental efforts have been made by the scientific community to com...
IMPETUS: Integrated Mechanisms, Phenotypes, and Translational Underpinnings of Chronic Pain after Surgery
Chronic postsurgical pain (CPSP) is a major healthcare burden, affecting nearly 20% of patients undergoing major surgery.CPSP is associated with diminished quality of life, mood di...
Utilizing Bioprinted Human Stem Cells for Molecular Screening via Multi-Material Strategies
Abstract Neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases, are fundamentally characterized by neuronal damage and cell death. Development of adul...
Cell-cell signaling and pattern formation in yeast
Project Summary / Abstract Pattern formation, the spatial organization of cells of different types, is central to the development and function of metazoans. Pattern formation also...
Microglial TREM2 Mediates Hippocampal Synaptic and Cognitive Sequela of Early Deprivation and Enrichment
PROJECT SUMMARY/ABSTRACT Childhood neglect accounts for 60% of all early life adversities and is associated with profound cortical thinning, hyperactivity, and cognitive deficits t...
Exploring PAR2 Trafficking in Oral Cancer: Implications for Pain Signaling and Drug Delivery
PROJECT SUMMARY Opioids remain the most efficacious, but insufficient, analgesic regimen for treating patients with oral cancer pain. Oral cancer pain is generated at the primary c...
Molecular mechanisms of oral deficiencies in Down syndrome
Project summary Down syndrome (DS) is caused by trisomy of all or part of human chromosome 21 (Hsa21) and is the most common genetic cause of intellectual disability. DS predispose...
Cross-linguistic influence during real-time processing in child heritage speakers
The project CLEAR (Cross-Linguistic influence during real-time procEssing in child heritAge speakeRs) investigates the role of crosslinguistic influence in real-time sentence proce...
SPECIMEN - Spectroscopic Investigation into the Mechanisms of Electron Bifurcation in [FeFe]-Hydrogenase for Green Catalysis Solutions
Improving solar fuel generating technologies and industrial catalysts are two essential aspects of tackling the ever-increasing issue of climate change. Electron bifurcating enzyme...
Virtual Demonstrator Second Phase
Purpose and goal:The goal is to together with partners define and document project methodology for virtual demonstrator in the aviation domain. This is phase two, which takes this...
A strategy for civilian-military innovation systems
Purpose and goal:The new geopolitical landscape has put dual-use between civilian and military applications in focus and the war in Ukraine has shown that a very high pace is possi...
Defense industry and civil prepareness through innovative startups
Purpose and goal:The innovation support system in Värmland consists of 145 sharp resources who have cutting-edge knowledge in important areas such as tech and AI, cyber security, p...
Uppsala infrastructure for dual use synergies
Purpose and goal:In order to increase cooperation between the civil and military sectors, which can contribute to strengthened Swedish military capability and at the same time prom...
CivMil HW - hardware innovation for dual use
Purpose and goal:The Södertälje Science Parks initiative Production Angels is a complement to Sweden´s incubators. Through cooperation between innovation environments and the Armed...
Innovation infrastructure for Civil-Military Cooperation
Purpose and goal:Aim: The project aims to develop a model and strategy for a national infrastructure that strengthens the cooperation between civil innovation environments and the...