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606,025 grants found
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East Sweden for national infrastructure Civil - Military synergies
Purpose and goal:The purpose of the project is to create the conditions for a strategic node that promotes cooperation between the civilian and military sectors, with a focus on de...
Type 2 Diabetes Mellitus and Vascular Contributions to Cognitive Impairment and Dementia (T2DM-VCID)
Project Summary/Abstract A significant gap in understanding is how suboptimal control of hyperglycemia from type 2 diabetes (T2DM) and prediabetes, particularly in young adults (18...
Risk Factors for End-Stage Glenohumeral Osteoarthritis
Project Summary/Abstract Glenohumeral osteoarthritis (OA) can be as debilitating as hip or knee OA, and in the US, shoulder arthroplasty rates for OA are rising more rapidly than h...
Integrating Reading and Attention Practices to Maximize Learning for Students with Co-Occurring Difficulties
Project Summary/Abstract Despite decades of research on reading disabilities, the efficacy of existing interventions for improving reading in upper elementary students (Grades 3 –...
Exopolysaccharide regulation in Aggregatibacter actinomycetemcomitans
ABSTRACT A hallmark of the oral bacterium Aggregatibacter actinomycetemcomitans’ biology and infectivity are its ability to form tenacious biofilms. Biofilm formation in the organi...
Examining the impact of state laws on intimate partner violence
Intimate partner violence (IPV) is common with over 7% of U.S. women reporting physical or sexual violence, and/or staking in the past year. Moreover, nearly 10% of pregnant people...
Concurrent eradication of pathogenic plasma cells and their precursors in systemic lupus erythematosus
PROJECT SUMMARY Systemic lupus erythematosus (SLE) is a chronic autoimmune disease. 90% of patients with SLE are women between the ages of 15 and 44. SLE is characterized by a hype...
Adaptation and Preliminary Evaluation of Energize-MBC: Cognitive Behavioral Therapy for Fatigue among Women with Metastatic Breast Cancer
PROJECT SUMMARY/ABSTRACT Our team’s long-term goal is to promote the health and well-being of “metavivors,” a growing population of individuals living long-term with metastatic can...
Determine the Role of Histone Methyltransferase ASH1L in Metastatic Prostate Cancer
Metastasis is the major cause of cancer mortality. Effective therapies are urgently needed for patients with metastatic diseases. Increasing evidence suggests that interactions bet...
A Randomized Trial of Chatbot for Prenatal Genetic Counseling
PROJECT SUMMARY Current recommendations from the American College of Obstetricians and Gynecologists (ACOG) call for all pregnant people to be offered screening and diagnostic test...
Dietary alteration of n-6 and n-3 fatty acids for chronic low back pain
ABSTRACT The NIH has declared that developing new non-addictive treatments for chronic pain is one of its top priorities. Certain polyunsaturated fatty acids are precursors to oxyl...
Mechanisms of Motor Superperformance
MECHANISMS OF MOTOR SUPERPERFORMANCE: ABSTRACT Clinical experience and world population-level data indicate that most neurological disability stems from motor dysfunction. Yet, spo...
Enabling comprehensive and user-friendly circular RNA analyses with circtools.cloud
Project Summary/Abstract Circular RNAs (circRNAs) have been studied for only one decade but have been implicated in many different disease settings such as cancer, neurological, an...
Molecular mechanisms in sweat gland innervation
PROJECT SUMMARY Eccrine sweat glands are the most abundant glands in human skin and are essential for thermoregulation and water balance. Patients with severe burn injuries and con...
Circulating metabolites as novel risk biomarkers for gastric cancer: a large multi-center prospective investigation
ABSTRACT Gastric cancer is one of the most common and deadly cancers globally, accounting for over one million new cancer diagnoses and 783,000 deaths in 2018. Infection of Helicob...
The Morehouse School of Medicine's Institute of Genomic Medicine Center for Genomic Diversity
Abstract – Overall This proposal outlines a program to establish a Center of Genomic Diversity at the Morehouse School of Medicine (MSM). Led by the Director of the Institute of Tr...
Administrative Core
Abstract This component of the application describes the role of the Administrative Core (AC) within the Institute of Translational Genomic Medicine (ITGM) and the MSM Center for G...
Workforce Development Core
PROJECT SUMMARY/ABSTRACT Education plays a crucial role in harnessing the full potential of genetic and genomic science to enhance health outcomes. However, it is challenging to at...
Community Engagement Core
Abstract: The premise of the Community Engagement Core (CEC) is to advance the science of community engagement toward increasing African American (AA) and Hispanic communities’ par...
A model system to study the inheritability of structural racism and discrimination through epigenomics
ABSTRACT Structural racism and discrimination (SRD) is a salient mechanism perpetuating racial gaps in health. Emerging studies have documented the impact of SRD on negative pregna...