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606,025 grants found
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NBER Coordinating Center on the Economics of AD/ADRD Prevention, Treatment, and Care.
OTHER PROJECT INFORMATION – Project Summary/Abstract NBER Coordinating Center on the Economics of AD/ADRD Prevention, Treatment, and Care This application proposes to establish a c...
Administrative Core
OTHER PROJECT INFORMATION – Project Summary/Abstract Administrative Core (Core A) The administrative core will provide organizational leadership to the Center consortium, and there...
Research Project Core
OTHER PROJECT INFORMATION – Project Summary/Abstract Research Project Core (Core B) The goal of the research project core is to support cutting edge new research projects on the ec...
Translation Core
OTHER PROJECT INFORMATION – Project Summary/Abstract Translation Core (Core D) The goal of the Translation Core is to encourage the application of findings from consortium research...
Stakeholder Engagement Core
OTHER PROJECT INFORMATION – Project Summary/Abstract Stakeholder Engagement Core (Core C) The stakeholder engagement core has two primary functions. The first is to inject in the r...
Novel Stabilization Catheter for His Pacing Lead Implant
ABSTRACT Heart failure (HF) is a nationwide epidemic with over 6 million afflicted patients and 600,000 new patients diagnosed each year. Many HF patients present with left bundle...
Mural cells contribution to vascular remodeling in flow induced pulmonary hypertension
Project Summary/Abstract: Pulmonary arterial hypertension (PAH) is a progressive vascular disorder characterized by narrowing and remodeling of the distal arterioles. Current treat...
Efficient low flow pump for pediatric extracorporeal membrane oxygenation
Project Summary The goal of this STTR proposal submission is to develop a new extracorporeal membrane oxygenation (ECMO) pump designed to efficiently accommodate the low flow rates...
Artificial intelligence based platform for peptide lead optimization.
ABSTRACT Peptides possess exceptional therapeutic qualities, with high potency, selectivity, and low toxicity. Challenges like short half-life and poor oral bioavailability of pept...
Development and Validation of a Computerized Adaptive Test of Fatigability
PROJECT ABSTRACT Fatigue is a common debilitating symptom that inhibits activity and functional recovery in hospitalized older adults. While clinicians consider treating fatigue to...
Development of a Novel Therapeutic Agent for Skin Fibrosis
Systemic sclerosis or scleroderma is an autoimmune rheumatic disease characterized by fibrosis of the skin and internal organs that has the highest case fatality among rheumatic di...
A podcast for the research community to share their stories on the difficulty of being good
Early career researchers can find it overwhelming to practise bioethics in their daily work as the health sector has become increasingly complex.Though the disease burden is most a...
World Health Summit: Enhancing Global Health Through Inclusivity and Global Reach
Since its inception in 2009 the World Health Summit (WHS) has become an important platform and convener of diverse stakeholders from all sectors to catalyze better solutions for a...
Flexible piezo film intravascular ultrasound arrays on guidewires and catheters
Coronary heart disease and peripheral artery disease are the leading causes of atherosclerotic morbidity along with stroke. More than a million percutaneous coronary and peripheral...
Computational tools for illuminating the dark matter of the human virome
Project Summary As greater understanding of the important role that the human microbiome plays in human health has unfolded it is increasingly recognized that there is a vast and u...
Imaging of macrophage trafficking with ultrasound
Project Summary Imaging of macrophage trafficking can reveal important molecular, cellular, and functional characteristics of the host tissue and support the discovery of new bioma...
Impact of benzalkonium chloride on gut microbiome and gut-liver interactions
Benzalkonium chlorides (BACs) are widely used antimicrobials in disinfecting products, medical products, and food processing industries, suggesting humans may be exposed chronicall...
ACL Reconstruction Rehabilitation with Exercise and Psychological Support
PROJECT SUMMARY Anterior cruciate ligament (ACL) rupture is a common knee injury in sports that is usually surgically treated with ACL reconstruction. Most patients expect to resum...
Genicular Artery Embolization for Reducing Pain in Medically Refractory Mild to Moderate Osteoarthritis: A Double-Blind, Randomized Sham-Controlled Pilot Study
PROJECT SUMMARY/ABSTRACT Knee osteoarthritis (KOA) is a pervasive and debilitating disease, affecting over 15 million people in the US alone. Symptoms include pain, stiffness, and...
Unraveling the Genomic Causes for Unsolved Leukodystrophy Patients by HiFi-GS
SUMMARY Leukodystrophies (LD) are a group of rare genetic disorders preferentially affecting cerebral white matter (myelin) in previously healthy children and is associated with ex...