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15,626 grants found
Showing 15,541 – 15,560 of 15,626 grants
Ventilator induced lung injury: translational and clinical studies
BakgroundMechanical ventilation (MV) is used in anaesthesia and intensive care as life-sustaining tool. When not correctly titrated, MV can lead to hyperinflation or cyclic opening...
Epidemiologi, patofysiologi och behandling av takotsubo syndrom
Bakgrund: Takotsubo syndrome (TS) is a novel syndrome with a substantial morbidity and mortality. Patients with TSmaintain normal or near-normal cardiac output despite extensive le...
Molekylära mekanismer för neuronal reglering av blodkärlsinflammation och ateroskleros
BakgrundÖverdriven inflammation förvärrar ateroskleros och kardiovaskulär sjukdom. Inflammation regleras av bl a immunceller och nervreflexer. Störningar i regleringen kan ge uppho...
Patient-specific computational modeling to predict intervention outcome and increase understanding of heart failure in congenital heart disease
Bakgrund:En procent av alla barn föds med ett hjärtfel. Antalet vuxna som lever med ett korrigerat hjärtfel ökar snabbt och många utvecklar hjärtsvikt som påverkar deras hälsa och...
Obstructive airway diseases in adults in western Sweden: computational phenotyping and clinical outcomes
Bakgrund:Current understanding of obstructive airway diseases indicates that they are heterogeneous syndromes, presenting with different distinct phenotypes. Advances in computatio...
Mast cell phenotypes in chronic airway diseases: emphasis on limiting detrimental effects on epithelial damage and anti-viral capacity
Bakgrund:En betydande andel patienter med kroniskt obstruktiv lungsjukdom (KOL) och astma har ihållande symtom och minskad livskvalitet trots behandling. Infektioner tros vara en v...
Iconic Scriptures in Colonial Punjab: Sikh Religion, Print Culture, and Politics
The project examines the historical processes of making religious scriptures iconic when humans create and ritualize the material form of printed books.This is done by documentatio...
Autonomy, Culture, Action: On Culture's Spheres of Political Action in the Neoliberal Welfare State
The project studies the possible domains of political action for culture and the arts today, by critically investigating histories of progressive cultural policy initiatives in the...
Does popular influence over policy lead to good outcomes?
Does popular influence over policy produce good outcomes? It is surprisingly hard to say.The highest standards of human well-being are generally found in established democracies. B...
Ventilator induced lung injury: translational and clinical studies
Bakground:Mechanical ventilation(MV) is used in anaesthesia and intensive care as life-sustaining tool. When not correctly titrated, MV can lead to hyperinflation or cyclic opening...
Coronary microvascular dysfunction a unifying pathophysiological mechanism of non-obstructive myocardial ischemia?
Bakgrund:Approximately 90% of the cardiac blood volume resides in the microvasculature. It has become evident that obstructive epicardial disease is not the only cause of myocardia...
The next generation of evidence-based personalized physical activity interventions to improve health outcomes after myocardial infarction
Background:The benefits of supervised center-based exercise as part of cardiac rehabilitation (exCR) for patients after myocardial infarction (MI) are undisputible, however, partic...
E!114787, ENVISAGE, DEVYSER
Purpose and goal:Objectives of the project was to develop and clinically validate an NGS-based assay and associated software for measurement of donor-derived cell-free DNA (dd-cfDN...
Activation of regenerative pathways by exercise training in patients with chronic obstructive pulmonary disease
Background: COPD is an increasing worldwide health problem characterized by progressive tissue destruction. Exercise training has been a cornerstone in COPD treatment for many year...
Immunoinflammation och fibros hos patienter som har pågående eller genomgången svår COVID-19 studerad med positron-emissionstomografi
Bakgrund:Patienter med svår COVID-19 har andningssvikt med allvarlig lunginflammation och betydande mortalitet. Immunoinflammationen medieras till stor del av neutrofila granulocyt...
Fertility intentions and fertility decline in Sweden
Over the past decade fertility rates in Sweden have declined somewhat unexpectedly. This development has occurred in tandem with even greater fertility declines in the other Nordic...
Kan vi bota långvariga besvär efter COVID-19 med hyperbar oxygen (HBO): En randomiserad placebokontrollerad läkemedelsprövning.
Bakgrund:We are currently running a multicenter randomized clinical trial (RCT) according to ICH-GCP treating acute COVID-19 with hyperbaric oxygen (HBO). Its one of few trials wit...
Rehabilitation of patients with long-covid-19 - development and evaluation of specific tailored interventions
Bakgrund: Long term symptoms after covid-19 were initially mainly reported in patients that required intensive care, however, post-covid-19 symptoms may also occur after so-called...
New Faces of the Folk Church - Lived Religion, Spiritual Practices and Theological Legitimacy
Research on lived religion has frequently turned its focus from institutions and organised religion to study the everyday life of laypeople. The purpose of the proposed study is to...
Risk, insjuknande och komplikationer av COVID-19 hos hjärt-kärl- och lungsjuka longitudinell nationell registerstudie med regelbunden datauppdatering
Bakgrund:Covid-19-pandemin utvecklas snabbt i Sverige och världen. Mer behövs om patienterna, deras riskfaktorer och prognos, samt kort-, medel- och långtidseffekter efter sjukdome...