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15,626 grants found
Showing 15,541 – 15,560 of 15,626 grants
Smooth muscle cell modulation by the MaR1-LGR6 duo: novel role in the resolution of human cardiovascular inflammation.
Atherosclerotic cardiovascular disease (ASCVD) is a progressive disease characterized by aberrant immune activation and chronic vascular inflammation as a result from a failure in...
Do AI generated outputs have contents?
This project asks: do the outputs of machine learning neural net AI systems (henceforth, ‘AI systems’) have contents i.e., do they have meanings, express propositions, or represent...
Driving tumour antigen presentation by RNA-mediated transdifferentiation
Immunotherapy has transformed cancer treatment, but targeting effectively refractory solid tumors remains a challenge due to poor T cell activation. Downregulation of antigen prese...
Investigating the regulation of the senescence-associated secretory phenotype (SASP) by mitochondrial DNA (mtDNA) metabolism for the development of novel senotherapies.
In response to various stresses such as DNA damage, telomere erosion, or oncogene activation, human cells can enter senescence. This process is characterized by irreversible prolif...
Unveiling the impacts of vapor pressure deficit on forest productivity
Atmospheric dryness, which is often quantified as a vapor pressure deficit (VPD), exerts significant influences on vegetation productivity and global carbon cycles. VPD is expected...
Improving Clinical Trials Reporting
This proposal will rigorously evaluate three approaches to reducing research waste and publication bias in clinical trials. The findings will provide a firm evidence base to inform...
VITNK - deciphering vitamin A and D regulation of human NK cells for cellular immunotherapy
Natural killer (NK) cells are cytotoxic innate immune cells that defend against viral infections and cancer. As cancer is one of the leading causes of death worldwide, more effecti...
Politico-bureaucratic relations in the context of decentralization: Understanding conflicts and outcomes in Jordan, Morocco and Tunisia
Decentralization reforms in the Global South have witnessed a surge since the 1980s, embraced by governments and international donors as a solution to myriad problems from poor pub...
Toward Perovskite-based Electrically Pumped Laser via Facile Facet Engineering
Beyound traditional III-V laser diodes, solution-processable solid-state lasing (SPSSL) has been in spotlight due to promising versatility and simplified fabrication for integratio...
The Geometry of Higher Symmetries
Symmetry structures are key to organizing the complexity of physical systems. In systems described by quantum field theories (QFTs) symmetries group observables, classify phases, d...
HYDRIDE: Hydrogenase Driven H2 production through Design and Evolution
Climate change is shaping up to be the greatest existential threat that humanity has ever faced. To combat climate change and the corresponding energy crisis, greenhouse gas emissi...
Redefining the landscape of ammonia electrooxidation, utilising molecular electrocatalysts
Fuel cells represent highly efficient and non-polluting power devices that convert the chemical energy of a fuel into electrical power. Ammonia, as a fuel, is considered a potent a...
Anthropocene Frontiers: Colonial Climate Science in Siberia and Central Asia
The AnthroFront project analyzes the relationship between climate science and colonial violence from the perspective of the Russian Empires Siberian and Central Asian frontiers in...
Study on the Biomechanical Mechanism of Patient-Orthosis Interaction Based on Subject-Specific Patient-Orthosis Coupling Musculoskeletal Model
Knee osteoarthritis (KOA) is a prevalent, chronic, degenerative, and multifactorial disease associated with pain, stiffness, and physical disability, and it is a significant publi...
Hi-NEAT (Hierarchical Nanoengineered Assemblies of Titania) sensor
The proposed research seeks to advance the state of the art in skin cancer diagnostics by developing an electrochemical sensor for tumour markers (or biomarkers) utilizing hierarch...
LIGNin-IRON complexes for removal of nano-plastics in enhanced coagulation-flocculation from water
Recent advances in lignin nanotechnology have opened up new possibilities not just for underutilized lignin side streams but also for hybrid organic-inorganic nanocomposites. One s...
A molecular and cellular mapping of the fenestrated vasculture of the circumventricular organs: from physiology to pathology.
In the brain, the blood vasculature harbours a unique specification: the Blood Brain Barrier (BBB), which restricts blood/brain exchanges to a select set of molecules. This particu...
Monitor Multiple Sclerosis evolution using body fluids derive cell-free epigenomics
Multiple sclerosis (MS) affects 2.8 patients worldwide, 700000 in Europe alone, and is characterized by subsequent phases of different severity which eventually evolve into a chron...
PERSONALIZED SUSTAINABLE SMART PATCH OMNIFICENCE
Today, the main research trends in decentralized personal health monitoring (PDHM) are on monitoring at longer periods, reducing motion artefacts, and multimodal monitoring. PERSIM...
Spin-dependent string fragmentation
The fragmentation process is one of the most intriguing and poorly understood phenomenon of quantum chromodynamics (QCD). It belongs to the non-perturbative domain of QCD and is us...