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606,025 grants found
Showing 29,641 – 29,660 of 606,025 grants
Identification of splice variant derived neo-antigens in head and neck squamous cell carcinoma as targets for tumor vaccine therapy
Title: Identification of splice variant derived neo-antigens in head and neck squamous cell carcinoma as targets for tumor vaccine therapy Abstract Immune checkpoint inhibitors (IC...
Towards a Comprehensive, Spatiotemporal Roadmap of Cancer Metastasis
PROJECT SUMMARY Cancer metastasis, which accounts for 8 million deaths worldwide annually, is a multistep process that includes the emergence of metastatic subclones in primary tum...
Deep-tissue targeted molecular imaging with a palette of NIR-II emissive DNA-stabilized nanoclusters
Project summary/abstract Advances in in vivo biomedical imaging are critical for revolutionizing the ability of researchers and clinicians to peer inside the living body. These adv...
Pathogen Data Network
Summary The Pathogen Data Network (PDN) will nucleate global networks around the mobilization of diverse biodata types, including host and pathogen genomics, transcriptomics, prote...
Translaryngeal Vibration for Hyperfunctional Voice Disorders
PROJECT SUMMARY / ABSTRACT High-quality research designs have demonstrated that voice therapy has a positive impact on hyperfunctional voice disorders associated with muscle tensio...
Community-Based Safety Training for the Mid-Atlantic Fishing Industry
Project Abstract - Fishing Partnership Support Services - Safety Training in the Mid-Atlantic Fishing Partnership Support Services (FPSS) will continue to use a community-based mod...
Community-Based Safety Training for the New England Fishing Industry
Project Abstract - Fishing Partnership Support Services – Safety Training in New England Fishing Partnership Support Services (FPSS) will continue to use a community-based model to...
Leveraging video logs as a bridge to pre-exposure prophylaxis (PrEP) with tailored messaging to Black women and their healthcare providers in Texas
Abstract Achieving the nation’s Ending the HIV (EHE) Epidemic plan goals will require a significant increase in access to and uptake of pre-exposure prophylaxis (PrEP) among cisgen...
An off the shelf alternative to fat transfer for soft tissue repair
Project Summary The goal of this Phase I SBIR program is the development of an optimized, off-the-shelf alternative to autologous fat grafting for soft tissue repair. Fat grafting...
NUCATS CTSA K12 Program at Northwestern University
Leveraging our experience as a KL2 program, we submit this Northwestern University Clinical and Translational Sciences Institute (NUCATS) K12 application in conjunction with the NU...
Commercial fishing vessel stability and primary prevention policy
Over the last 30-years, safety and health knowledge has increased and helped reduce fatali�es through secondary preven�on a�er vessel casualty occurs, yet vessel instability at sea...
Developing Hyperpolarized Gas MRI signatures to detect and manage acute cellular rejection
ABSTRACT Lung transplantation (LT) is the only definitive therapy for many patients with end-stage lung diseases, but many LT recipients experience allograft failure with high morb...
Defining the landscape of bacterial-colonized microniches in tumors and their role in intratumoral heterogeneity.
PROJECT SUMMARY/ABSTRACT Within a patient’s tumor, malignant cells are surround by a complex and dynamic collection of cell types, which includes the intratumoral microbiota. Howev...
Long-term Impact and Value of Infant Genomic Sequencing (LIVING)
PROJECT SUMMARY/ABSTRACT The use of genomic sequencing at birth to inform the ongoing care of children has generated great enthusiasm. Genomic sequencing can act as a screening too...
Social Genomic Mechanisms Linking Structural Racism, Perceived Discrimination, and Breast Cancer Survival
PROJECT SUMMARY Women living in historically redlined neighborhoods impacted by structural racism and discrimination (SRD) have shorter breast cancer (BCa) recurrence-free survival...
Understanding Racial/Ethnic Disparities in Clinician Concordance with Hypertension Treatment Guidelines and Blood Pressure Control
Project Summary/Abstract Despite an equal hypertension treatment rate between Blacks and Whites (79.7% vs. 79.1%), racial/ethnic disparities in blood pressure (BP) control persist...
Are you REDDE? Expanding a Mobile Vessel Safety and Training Service for Northeast Fishermen
Abstract: Commercial fishermen spend one third of their lives at sea participating in one of the most dangerous jobs in the world. Vessel masters are required by law to keep onboar...
Evolved Molecules that Destroy Cancer Relevant Proteins
ABSTRACT Cancer research is often driven by hypotheses that postulate that a specific protein is important for the disease, hypotheses often tested by adding an antibody to that sy...
Active-H2O: Sensor driven smart faucet to empower independent living for individuals impacted by Alzheimers disease and dementia
Alzheimer's disease (AD) is a progressive brain disorder affecting cognitive/functional abilities, including ability to perform activities of daily living (ADLs). Globally, &g...
Wastewater surveillance to enhance the public health response to HIV and TB in Eswatini
PROJECT SUMMARY Eswatini was among the first countries to achieve the UNAIDS 95, 95, 95 targets resulting in substantial declines in HIV incidence and TB prevalence. Despite this a...