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606,025 grants found
Showing 28,841 – 28,860 of 606,025 grants
PM2.5 Metals, Oxidative Potential, Exposure, and Risk Assessment (PM OPERA): A National Morbidity and Mortality Study
Project Summary Outdoor fine particulate air pollution (PM2.5, particles with aerodynamic diameter < 2.5 𝜇m) is a leading cause of global morbidity and mortality, contributing t...
Xanthine oxidase mediates the vascular dysfunction with direct and in-utero electronic cigarette exposure
ABSTRACT The adult prevalence of Electronic cigarettes (Ecigs) is ~5%, with young adults having the highest prevalence, and 56% of the young adults were never smokers, which includ...
Leveraging biomarkers for personalized treatment of alcohol use disorder comorbid with PTSD
Project Summary/Abstract Alcohol use disorder (AUD) and post-traumatic stress disorder (PTSD) are highly comorbid, presenting a clinical challenge with limited treatment efficacy....
Comprehensive Cancer Center Support Grant
Cervical cancer elimination as a public health problem has become a reality if we focus on the uptake of three evidence-based tools: HPV vaccination, cervical cancer screening, and...
Mayo CCCG (Supp) - Impact of Multi-Channel Communication Campaigns on Cancer Prevention, Control and Survivorship (CaPCaS) in Black, Hispanic, Rural, and Sexual and Gender Minority Populations
ABSTRACT This application is being submitted by the Mayo Clinic Comprehensive Cancer Center (MCCCC) to extend the period of support for the P30 Administrative Supplement for Multi-...
Communication in American Indians thru Strategies for Equity 4 Cancer (CASE4Cancer)
PROJECT SUMMARY: Cancer continues to be the top cause of death for American Indians (AIs) in North Carolina. With higher rates of colorectal cancer (CRC) late stage diagnosis and m...
Metal-Mediated C-H Radiofluorination for Rapid Access to PET Imaging Agents
Project Summary/Abstract Fluorine is an essential constituent of many commercial molecules, including (radio)pharmaceuticals, agrochemicals, and functional materials. Fluorine-19 (...
TAZ-driven Regulation of Tumor Microenvironment in Triple-Negative Breast Cancer
ABSTRACT Breast cancer (BC) is a complex and heterogeneous neoplastic disease with a high incidence and mortality. BC can be divided into clinical, histopathologic, and molecular s...
Center for Health Equity Research Institute II: Community-engaged biomedical research training and mentored experiences for early career faculty
Project Summary The goal of this IPERT renewal application, submitted by California State University, Long Beach (CSULB) Center for Health Equity Research (CHER), is to provide edu...
P30 Administrative Supplement for Multi-Channel Communication Campaigns for Improvements in Cancer Education and Outcomes (MICEO) in Underserved Populations
PROJECT ABSTRACT Childhood cancer survivors are a high-priority, underserved population for HPV vaccination. They are less likely to be vaccinated when compared to the general popu...
Triclosan, pubertal hormones, and the gut microbiome: implications for neurobehavior
PROJECT SUMMARY Despite potential lifelong consequences of gut microbiome dysbiosis, little is known about environmental factors that influence its diversity and composition, inclu...
Multi-antigen-specific CAR T cells to treat acute myeloid leukemia
PROJECT SUMMARY Chimeric antigen receptor (CAR) T cell therapy is a novel form of cellular immunotherapy in which the antigen specificity of T cells is redirected using synthetic r...
Discerning mechanisms of semaphorin 7A-mediated tumor progression via immunoevasion
Project We Summary/Abstract have identified that semaphorin 7a (SEMA7A)—a signaling molecule that activates integrin-β1 signaling in cancer—is upregulated in postpartum breast canc...
Deep-learning assisted photoacoustic histology for real-time intraoperative pathological diagnosis
Project Summary Despite the advances in cancer treatment, surgery remains the cornerstone, and more than 80% of cancer patients have a surgical procedure at some point in their can...
Differentiating the Physiological Sources of Modulated Voice
Project Summary Essential tremor (ET) is the most prevalent movement disorder affecting approximately 25 million people worldwide. Up to sixty-two percent of patients with ET devel...
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY)
PROJECT SUMMARY/ABSTRACT This proposal aims to leverage and enhance existing resources to create a robust, interoperable set of CDEs that will facilitate better understanding, char...
Immune and transcriptomic biomarkers of progressive oral premalignant lesions
PROJECT SUMMARY Oral squamous cell carcinoma (OSCC) is the 6th leading cause of cancer-related mortality worldwide. OSCC is curable with favorable survival outcomes if detected ear...
Impact of Historically Black Colleges and Universities on Late-life Cognition in Black Adults
PROJECT SUMMARY/ABSTRACT Black-White inequities in Alzheimer’s Disease and Related Dementia (ADRD) are a pressing public health problem: prevalence is almost double for Black adult...
UJMT – Morehouse School of Medicine Supplement
ABSTRACT The UJMT Fogarty LAUNCH Program has an established track record in global health research, supporting over 270 US and international trainees to date. While the program has...
Respiratory Effects, Metal and Aldehyde exposure from e-cigarette use in young adults (REMA)
PROJECT SUMMARY My long-term goal is to become an independent investigator focusing on how pollutant exposures may adversely affect respiratory health and identify measures to effe...