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606,025 grants found
Showing 24,861 – 24,880 of 606,025 grants
Developing a foundation for a novel emergency department-based intervention to address inappropriate aspirin
PROJECT SUMMARY/ ABSTRACT Aspirin is one of the most used drugs in the world. Unfortunately, many older adults will consume aspirin without an established indication, a scenario in...
Cell Death Regulation by Pro-Apoptotic BOK in Tauopathies
PROJECT SUMMARY Alzheimer's disease (AD), and other neurodegenerative tauopathies, are defined by their pathologic accumulation of overexpressed, hyperphosphorylated, and olig...
Deep integrative analysis of Hi-C data
Project Summary/Abstract Chromatin 3D structure plays an important role in fundamental genomics processes. A variety of experimental methods, such as Hi-C, GAM, SPRITE, and HiChIP,...
Improving hand kinematic predictions from implanted EMG in humans and monkeys
Project Summary There are millions of people worldwide with debilitating upper limb amputations. While electrical signals from residual muscle can provide some function, every ampu...
COMBINATION HIGH-LET MOLECULAR RADIOTHERAPY OF RELAPSED REFRACTORY NEUROBLASTOMA
PROJECT SUMMARY There is a critical need for more effective treatments for metastatic and relapsed neuroblastoma (NB), the most commonly diagnosed extracranial solid cancer in chil...
Interplay between DNA base excision repair and transcriptional regulation
PROJECT SUMMARY Guanine-rich G-quadruplex (G4) forming sequences are enriched at promoter proximal regions of the genome, in particular those of cancer and DNA repair-related genes...
Neural Mechanisms Underlying Cognitive Contributions to Walking as an Early Marker for Risk of Alzheimer’s Disease and Related Dementias
Project Summary/Abstract Early detection of Alzheimer's Disease and Related Dementias (ADRD) is essential for implementing interventions that can slow cognitive decline, benef...
Epigenetic biomarkers of cardiovascular risk in African American Women
ABSTRACT The main goal of this project is to assess the contribution of epigenetics to cardiovascular risk in African American women. Cardiovascular disease substantially impacts A...
CLIMAte-related Exposures, Adaptation, and Health Equity (CLIMA) Center
PROJECT SUMMARY (OVERALL) The University of Southern California (USC) CLIMAte-Related Exposures, Adaptation, and Health Equity (CLIMA) Center's mission is to build a community...
Administrative Core
PROJECT SUMMARY (ADMINISTRATIVE CORE) The mission of the University of Southern California (USC) CLIMAte-Related Exposures, Adaptation, and Health Equity (CLIMA) Center is to devel...
The role of vulnerability and adaptation on the effects of co-occurring heat, air pollution, and wildfire on heart failure hospitalizations
PROJECT SUMMARY (RESEARCH PROJECT 1: THE ROLE OF VULNERABILITY AND ADAPTATION ON THE EFFECTS OF CO-OCCURRING HEAT, AIR POLLUTION, AND WILDFIRE ON HEART FAILURE HOSPITALIZATIONS) To...
The Role of Adaptation and Resilience in a Changing Climate: Cardiovascular Risk and Allostatic Load Among Youth
PROJECT SUMMARY (RESEARC PROJECT 2: The Role of Adaptation and Resilience in a Changing Climate: Cardiovascular Risk and Allostatic Load Among Youth) Climate change (CC) is rapidly...
Community Engagement Core
PROJECT SUMMARY (COMMUNITY ENGAGEMENT CORE) The University of Southern California (USC) CLIMAte-Related Exposures, Adaptation, and Health Equity (CLIMA) Center’s Community Engageme...
Methods Development Research Core
PROJECT SUMMARY (METHODS DEVELOPMENT RESEARCH CORE) The University of Southern California (USC) CLIMAte-Related Exposures, Adaptation, and Health Equity (CLIMA) Center’s Methods De...
Antibiotic Prophylaxis to Prevent Obesity-related Induction Complications in Nulliparae at Term (APPOINT 2.0)
Project Summary/Abstract Obesity increases the risk of pregnancy complications, including puerperal infections and cesarean delivery, and risk rises with increasing body mass index...
Predicting Intervention Outcomes in Reading Disabled Students Using In-School Cognitive Neuroscience
PROJECT SUMMARY/ABSTRACT Reading disability (RD) is the most common neurodevelopmental disorder, affecting approximately 9% of children. Children with RD have significant difficult...
Center for Transformative Infectious Disease Research on Climate, Health and Equity in a Changing Environment (C-CHANGE)
Some of the greatest human health impacts from climate change are mediated by infectious diseases. Billions are at risk annually from malaria alone, and viral pathogen spillover ev...
Center for Transformative Infectious Disease Research on Climate, Health and Equity in a Changing Environment (C-CHANGE)
The Administrative Core (AC) has primary responsibility for overseeing and facilitating all aspects of the Center for Transformative Infectious Disease Research on Climate, Health...
Center for Transformative Infectious Disease Research on Climate, Health and Equity in a Changing Environment (C-CHANGE)
PROJECT 1 PROJECT DESCRIPTION Our proposed studies will investigate how climate change affects risk of spillover of zoonotic infections from bats. Our work will help identify evide...
Project 2 - Center for Transformative Infectious Disease Research on Climate, Health and Equity in a Changing Environment (C-CHANGE)
PROJECT 2 SUMMARY/ABSTRACT Vector-borne diseases (VBDs) are a significant human health burden around the world and are linked with climate change in complex ways. In terms of vecto...