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606,025 grants found
Showing 24,621 – 24,640 of 606,025 grants
Building Safety Guards into LLMs for Trustworthy Automatic Simplification of Medical Documents
Abstract Texts describing medical advances are of keen interest to the general public. However, reliable medical evidence is largely disseminated in peer-reviewed journal articles...
Uncovering Causal Protein Markers to Characterize Pancreatic Cancer Etiology and Improve Risk Prediction
Pancreatic cancer (PC) is the third leading cause of cancer mortality in the United States. The vast majority of PC are pancreatic ductal adenocarcinoma (PDAC). The etiology of PDA...
Enabling mRNA Therapies for Pediatric High-Grade Gliomas
Diffuse midline glioma (DMG) is a lethal pediatric brain tumor without a cure and with a poor prognosis. The H3K27M mutation is present in 80% of DMG patients and is the primary dr...
Hemin Production by Veillonella: A Novel Mechanism in Inhibiting P. gingivalis Hemolysis
SUMMARY/ABSTRACT Periodontal disease, a widespread global health issue, predominantly originates from dental plaque, which an intricate polymicrobial biofilm. Within this milieu, V...
Confidentiality in use of health insurance coverage for reproductive health services
Enhancing Policy Impact for Reproductive Health Equity (EnPIRHE) Project Summary/Abstract- 30 lines The World Health Organization affirms that sexual and reproductive health (SRH)...
Effect of aerosolized tobacco and cannabis products on Streptococcus mutans and Candida albicans interkingdom cariogenicity
PROJECT SUMMARY Vaping of aerosolized tobacco and cannabis products using electronic nicotine delivery devices (ENDS) is increasingly popular among adolescents and young adults. Th...
Distance-based Exercise to preserve Function and prevENt Disability (DEFEND)
PROJECT SUMMARY Many cancer survivors experience challenges in performing daily activities and loss of work productivity due to the adverse effects of cancer and its treatments, re...
Partners in Research: Building capacity for community-driven research to advance health equity
ABSTRACT Structural factors of health inequities are the systemic and societal conditions that contribute to disparities in health among different populations. These disparities of...
Federated learning algorithms to overcome statistical and algorithmic bias and privacy concerns in machine learning for health
Project Summary Federated learning has emerged as a promising technique in biomedical research, providing the potential to construct robust common machine learning models with data...
Cultivating programmatic efforts to optimize the conduct and implementation of NCI-funded clinical trials
Dr. Cathy Eng is an exemplary Clinician Scientist who, throughout her career, has held numerous roles within the National Clinical Trials Network (NCTN) and is viewed, by her peers...
Neural Correlates of Cognitive-Motor Interactions in ADRD Gait
PROJECT SUMMARY NIH RFA AG-24-041 requests applications to determine the neural mechanisms that underlie the association between gait and cognition in aging and Alzheimer's di...
Comprehensive Analysis and Multi-Omics Data Integration for Cancer-Related Studies
Project Summary/Abstract I am a principal data scientist and bioinformatics manager of The Experimental and Computational Genomics Core in the Sidney Kimmel Comprehensive Cancer Ce...
Vulnerability of the ascending arousal network to alpha-synuclein pathology
Cognitive fluctuations –termed “the Lewy Body Roller Coaster” by some families – are a debilitating symptom of Lewy body disorders (LBD), an Alzheimer’s disease related disorder th...
IGF-1 and Innate Immunity in Neonatal Brain Injury
Abstract Neonatal Intraventricular hemorrhage (IVH) originates from the underdeveloped germinal matrix, a site of cellrapid cell division adjacent to the lateral ventricles of the...
POINT of CARE: PrOviding an Innovative New Triage and Treatment strategy for Cervical cAncer scReening Efficiency
PROJECT SUMMARY Although preventable, cervical cancer is a leading cause of mortality in low- and middle-income countries (LMIC). Infection with high-risk human papillomavirus (HPV...
Novel Statistical Models for Intensive Longitudinal Analyses of Cancer Control Behaviors
PROJECT SUMMARY This project will develop, test, apply, and disseminate multilevel statistical models and software for estimating effects of intraindividual means, variances, slope...
Whole genome sequencing analysis of hidradenitis suppurativa
Project Summary Hidradenitis suppurativa (HS) is a multifactorial chronic, debilitating, inflammatory skin disorder characterized by painful nodules, abscesses, sinus tracts, and s...
Advancing breast cancer risk assessment for Black women
ABSTRACT Effective treatment schemes have reduced breast cancer mortality, but precise identification of women at increased risk of developing breast cancer, to personalize screeni...
Developing an Innovative Genomic Data Science Curriculum: Interdisciplinary Modules for Undergraduate Education
NOFO: RFA-HG-23-002 Title: Developing an Innovative Genomic Data Science Curriculum: Interdisciplinary Modules for Undergraduate Education Project Abstract Computational Genomic Da...
Theta burst subthalamic nucleus deep brain stimulation for cognitive and motor improvements in Parkinson's Disease
Lewy body dementia (LBD) is the second most common cause of dementia after Alzheimer’s disease. In particular, Parkinson’s Disease (PD) progression has been associated with LBD and...