Browse All Grants
606,025 grants found
Showing 34,481 – 34,500 of 606,025 grants
(Project 3) Extracellular Vesicles in Monitoring and Treatment of Dystrophinopathy
Principal Investigator: Nizar Saad Project Summary/Abstract Title: Extracellular Vesicles in Monitoring and Treatment of Dystrophinopathy. X-linked recessive Duchenne Muscular Dyst...
NonInvasive Virtual Biopsy for Determining Bone Turnover in Chronic Kidney Disease
PROJECT SUMMARY / ABSTRACT Extremes of bone turnover are common in patients with chronic kidney disease (CKD), a population with exceptionally high fracture risk. Medical managemen...
Advancing ADPKD Treatment with GLP-1RA: A Study of Glucagon-Like Peptide-1 Receptor Agonists' Efficacy, Safety, and Mechanism
Project Summary Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder that leads to kidney failure. The only approved treatment to decelerate kidney d...
Emerging role of oral spirochetes to promote neuroinflammation and dysfunction
Periodontitis is a common chronic inflammatory condition of the tooth-supporting tissue, affecting up 50% of the population and two-thirds of the elderly in the United States. Prog...
Simultaneous two-photon imaging and two-photon manipulation of neural activity in freely behaving mice
Simultaneous two-photon imaging and two-photon manipulation of neural activity in freely- behaving mice The ability to record and manipulate neural activity in freely-behaving mice...
Assessing the role of SP140 in enhanced resistance to Cryptococcus neoformans
Project Abstract The HIV/AIDS associated fungal pathogen Cryptococcus neoformans (Cn) is responsible for 20% of global HIV-related mortality and has been designated on the World He...
Simian Collective Conference
PROJECT SUMMARYThis application is a request for funds to support a conference titled the ‘Simian Collective’ (SimCo) that highlights nonhuman primate neuroscience research in the...
Impact of mast cell heterogeneity on Osteoarthritis
SUMMARY Osteoarthritis (OA) is a highly prevalent and debilitating disease, affecting over 27 million people in the US. Its risk factors include aging, joint injury, obesity, and t...
Zebrafish Habitat Expansion
Abstract UMaine’s Zebrafish Facility is critical to the success of most NIH funded faculty at UMaine. Overall, 12 UMaine faculty, their technicians, undergraduate, and graduate stu...
Training in Research Undergraduate Experience through the Rutgers Addiction Research Center: The TRUE RARC Scholar Program
PROJECT SUMMARY We propose to develop an undergraduate research program that promotes the advancement of students from underrepresented (UR) groups in the field of addiction resear...
Estrogen and Mechanisms of Psychotic-like Experiences in the Transition to Adolescence
PROJECT SUMMARY Biological females develop psychotic disorders later than males. One leading theory that explains this phenomenon is the estrogen hypothesis, which proposes that ri...
Exploring Work Accommodations for Low-Wage Workers with Chronic Pain-Related Conditions: A Multi-Level Explanatory Sequential Mixed-Methods Study
Project Summary/Abstract Chronic conditions pose a disproportionate burden on low-wage workers, exacerbating the adversity and health inequities of this population. Chronic pain-re...
ADEPT-ICU: Attenuating Depression with Internet Cognitive Behavioral Therapy (CBT) to Slow Cognitive Decline in Older Intensive Care Unit (ICU) Survivors
PROJECT SUMMARY/ABSTRACT Alzheimer’s disease and related dementias (ADRD) affect 47 million people worldwide with an annual global cost of $818 billion. The risk of developing ADRD...
Conference on ADRD Research among Diverse Latinos (CARDL)
Project Summary The proposed Conference on ADRD Research among Diverse Latinos (CARDL) is based on the cells-to-society framework, and uses the SOL-INCA conceptual model for addres...
Leveraging Project ECHO for improved cervical cancer screening in Ethiopia: An implementation study of integrated HPV selfsampling in HIV care centers
PROJECT ABSTRACT Each year, more than 500,000 women are diagnosed with cervical cancer (CxCa), a preventable cancer caused by human papillomavirus (HPV) that disproportionately bur...
Using Machine Learning and Sensing to Contextualize Hyperactivity Measurement on Wearable Devices
PROJECT SUMMARY/ABSTRACT ADHD is the most common early childhood diagnosis, affecting around 9% of US children. LemurDx is a software system that uses state-of-the-art sensor techn...
Development of the novel mu-opioid receptor antagonist methocinnamox (MCAM) for preventing relapse and overdose
PROJECT SUMMARY/ABSTRACT In response to PAR-22-202 “Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional),” this revised applicatio...
Our Healing Journey: A Cultural and Traditional Response to the Opioid Epidemic
Abstract “Our Healing Journey: A Cultural and Traditional Response to the Opioid Epidemic” Generally, there are greater negative consequences associated with substance misuse among...
Effects of social isolation and loneliness during early life on neurocognitive development and addiction
Project Summary Social isolation (SI) and loneliness are associated with adverse health outcomes and are serious public health risks throughout life. In early life, SI has well kno...
Accelerated Brachytherapy Forward Chemoradiation Therapy (ABC-RT) for Cervical Cancer
PROJECT SUMMARY Survival from cervical cancer is stagnating in the United States. Despite many intervening clinical trials, the standard of care (SOC) definitive chemoradiation the...