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606,025 grants found
Showing 34,301 – 34,320 of 606,025 grants
Aquisition of a Orbitrap IQ-X Mass Spectrometer System with Vanquish Flex UHPLC System for Nucleic Acid Adductomics
PROJECT SUMMARY Funds are requested to purchase a Thermo Fisher Scientific Orbitrap IQ-X Mass Spectrometer System with Vanquish Flex UHPLC System (IQ-X) to establish a unique omics...
Light Sheet Microscope for Multi-View Imaging of Living and Optically Cleared Samples
Project Summary / Abstract This shared instrument proposal requests funding for a Zeiss Light Sheet 7 to be incorporated into the MicRoN (Microscopy Resources on the North Quad) co...
NAEOTOM Alpha Photon-Counting CT Scanner
Project Summary/Abstract This is a request to upgrade our current Siemens SOMATOM Force research energy integrating CT scanner to a newly released photon-counting CT scanner (Sieme...
State-of-the-Art Preclinical PET/CT Imaging System
Project Summary/Abstract State-of-the-Art Preclinical PET/CT Imaging System Yale University PET Center The goal of this proposal is to replace an end-of-life Positron Emission Tomo...
TimsTOF-fleX MALDI-2 mass-spectrometer
PROJECT SUMMARY The Advanced Science Research Center (ASRC) of the City University of New York (CUNY) is requesting funds from NIH through the High-End Instrumentation program to p...
Small Animal Ultrasound - Vevo F2
PROJECT SUMMARY This proposal would obtain funds for the purchase of a FUJIFILM VisualSonics Vevo F2 small animal ultrasound imaging system for installation in the TI2EHM core at T...
Ultra-High Field Translational MRI Scanner
Project Summary This High End Instrumentation grant proposal seeks to replace the 7T MRI scanner that is currently operational at the Lucas Center for Imaging (LCI) at Stanford Uni...
Super Resolution 3D-STED Microscope for a Core Facility
Project Summary We are seeking funding to procure an Aberrior FACILITY Line Stimulated Emission Depletion (STED) super- resolution microscope system. This equipment will bolster th...
Developing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery
Project Summary Alcohol use in the Unites States is a public health crisis that costs the U.S. health care system $249 billion annually. However, only about 10% of individuals with...
Calculating the Components of Work of Breathing in Neonates with Bronchopulmonary Dysplasia
Project Summary Neonates can now survive premature birth from as early as 22 weeks’ gestation, but often suffer from bron- chopulmonary dysplasia (BPD) – chronic lung disease of pr...
Impact of wearable biofeedback for the rehabilitation and tele-rehabilitation of neurogenic dysphagia
PROJECT SUMMARY/ABSTRACT Oropharyngeal swallowing disorders (a.k.a. dysphagia) are among the most common and dangerous manifestations of many neurologic conditions. Critically, dys...
Targeting Nonalcoholic Fatty Liver Disease during the reproductive period to improve women's health outcomes
Nonalcoholic fatty liver disease (NAFLD), and its progressive form, nonalcoholic steatohepatitis (NASH), is the leading cause of cirrhosis and liver transplantation in women, yet i...
Novel 3D Quantitative Dynamic MRI to Characterize Obstructive Sleep Apnea
SUMMARY An estimated 30-70% of obstructive sleep apnea (OSA) patients are intolerant to first-line continuous positive airway pressure (CPAP) therapy for a variety of reasons. A va...
Determining the role of the creatine pathway regulation of intestinal goblet cell development in colitis
Proposal Summary Inflammatory bowel disease (IBD), comprised of ulcerative colitis and Crohn's disease, contributes to significant morbidity and mortality in the United States...
Effect of physical rehabilitation on molecular markers of frailty in heart failure
PROJECT SUMMARY/ABSTRACT Heart failure (HF) with preserved ejection fraction (HFpEF) is characterized by functional impairment, is highly prevalent in older persons, causes substan...
Developing shared medical appointments for informal caregivers of Alzheimer’s and Dementia patients to improve knowledge, communication, and advanced planning
Project Summary The prevalence of Alzheimer's Disease and related Dementias (ADRD) is expected to triple by 2060, affecting about 14 million Americans. As ADRD progresses, sym...
DEVELOPING A NATURALISTIC PARADIGM FOR EARLY DETECTION OF COGNITIVE IMPAIRMENT
PROJECT SUMMARY/ABSTRACT Early detection of cognitive decline in older adults (OA) is a public health priority. The pathology of Alzheimer's disease (AD) begins more than 20-y...
A Learning Health System Approach to Improve the Effectiveness of Blood Transfusions during Septic Shock
PROJECT SUMMARY/ABSTRACT Septic shock is a common, often fatal, dysregulated host response to infection that results in acute circulatory failure. Almost all patients with septic s...
A Telehealth Intervention to Increase Patient Preparedness for Surgery in Latinas
PROJECT SUMMARY This application is for an NIDDK K23 award for Dr. Gabriela E. Halder, a Female Pelvic Medicine and Reconstructive Surgeon (FPMRS) at the University of Texas Medica...
Role of mTOR Hyperactivation in Pulmonary Vascular Remodeling
Project Summary Pulmonary hypertension (PH) is a devastating lung disease characterized by pulmonary vascular remodeling and associated with high morbidity and mortality. Discovery...