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Showing 28,76128,780 of 606,025 grants

Active OTHER RESEARCH-RELATED
Adaptation and pilot testing of a family-centered intervention to improve long-term outcomes for survivors of acute respiratory failure
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of North Carolina Chapel Hill United States 2024 – 2029

This is an application for a five-year mentored patient-oriented research career development award (K23). The overall goals are to 1) adapt and pilot test a family-centered interve...

$1.82M
USD
Completed SBIR-STTR RPGS
Wearable Continuous Drug Monitoring Device for Personal Medications in Opioid Use Disorders (CDM-MOUD)
NATIONAL INSTITUTE ON DRUG ABUSE Labsys, Llc United States 2024 – 2025

ABSTRACT LabSys’s objective is to create a transformative wearable patch, designed as a low-cost Continuous Drug Monitoring Device for Opioid Use Disorders (CDM-MOUD). Our state-of...

$2.94M
USD
Active OTHER RESEARCH-RELATED
Determining the Role of Spp1+ Macrophages in Muscle Regeneration in Peripheral Arterial Disease
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Duke University United States 2024 – 2027

PROJECT SUMMARY This proposal presents a three-year research career development program focused on elucidating the molecular mechanisms and clinical significance of a pathologic ma...

$1.53M
USD
Active OTHER RESEARCH-RELATED
Noninvasive molecular imaging of complement biomarkers in kidney disease
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... University of Colorado Denver United States 2024 – 2026

PROJECT SUMMARY/ABSTRACT This K99/R00 application aims to provide support for Dr. Felix Poppelaars, a talented postdoctoral fellow in the laboratory of Dr. Joshua Thurman, to condu...

$900K
USD
Active RESEARCH CENTERS
The Montana Clinical and Translational Research Center
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Montana United States 2024 – 2029

Overall Project Summary / Abstract. With just over a million people in the entire state, Montana lacks an adequate healthcare infrastructure throughout our rural areas, contributin...

$21.79M
USD
Active RESEARCH CENTERS
Administrative Core
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Montana United States 2024 – 2029

Administrative Core Project Summary / Abstract. The Montana Clinical and Translational Research Center (Montana CTRC) will be led by an experienced Administrative Core, and will wo...

Active RESEARCH CENTERS
Health Research Core
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Montana United States 2024 – 2029

Health Research Core Project Summary / Abstract. The long-term goal of the Health Research (HR) Core of the Montana Clinical and Translational Research Center (Montana CTRC) is to...

Active RESEARCH CENTERS
Professional Development Core
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Montana United States 2024 – 2029

Professional Development Core Project Summary / Abstract. Professional development is a key ingredient for the Montana Clinical and Translational Research Center’s (CTRC) overall g...

Active RESEARCH CENTERS
Community Engagement and Outreach Core
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Montana United States 2024 – 2029

Community Engagement and Outreach Core Project Summary / Abstract. The long-term goal of the Community Engagement and Outreach (CEO) Core is to strengthen community- engaged clinic...

Active RESEARCH CENTERS
Research Design, Compliance, and Data Management Core
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES University of Montana United States 2024 – 2029

Research Design, Compliance, and Data Management Core Project Summary / Abstract. Strong research design, data analysis, and study implementation expertise are key components of ri...

Active NON-SBIR/STTR RPGS
Leveraging Community-Engaged Research to Co-Create Youth Vaping Prevention with Urban Indigenous Communities of the Southwest
NATIONAL INSTITUTE ON DRUG ABUSE Arizona State University-Tempe Campus United States 2024 – 2029

Leveraging Community-Engaged Research to Co-Create Youth Vaping Prevention with Urban Indigenous Communities of the Southwest ABSTRACT The prevalence and early initiation of nicoti...

$6.25M
USD
Completed NON-SBIR/STTR RPGS
Evaluating the associations of hearing loss with cognitive and brain health outcomes in midlife
NATIONAL INSTITUTE ON AGING Kaiser Foundation Research Institute United States 2024 – 2026

Project Summary Emerging evidence suggests hearing loss may be a modifiable risk factor for Alzheimer's disease (AD) and related dementias (ADRD). Midlife (ages 45-65) could b...

$2.63M
USD
Completed NON-SBIR/STTR RPGS
Next-generation Lasers for Enabling Ultrafast Functional Pulmonary MRI
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Wayne State University United States 2024 – 2026

PROJECT SUMMARY (30-line limit) Deadly lung diseases such as chronic obstructive pulmonary disease, asthma, lung injury, constrictive bronchiolitis, and pulmonary fibrosis affect &...

$2.31M
USD
Completed NON-SBIR/STTR RPGS
Improving Incontinence Support for Family Caregivers and Persons Living with Dementia
NATIONAL INSTITUTE ON AGING University of California, San Francisco United States 2024 – 2026

PROJECT SUMMARY There is a fundamental gap in our understanding of how best to care for persons living with dementia (PLWD) and urinary incontinence (UI), many of whom are being ca...

$2.46M
USD
Active NON-SBIR/STTR RPGS
Elimination of slice alignment errors in 2-dimensional structural MRI
NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOEN... University of Maryland Baltimore United States 2024 – 2026

Project Summary: The goal of the proposed project is to develop and validate a novel motion correction technique for 2D T2-weighted structural MRI of the brain. Head motion continu...

$2.09M
USD
Active OTHER RESEARCH-RELATED
Pre-Transplant Multiomic Profiling to Quantify The Risk of Rejection Following Heart Transplantation
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Ut Southwestern Medical Center United States 2024 – 2029

PROJECT SUMMARY______________________________________________________________________ One-third of heart transplant recipients will develop acute rejection of their new heart withi...

$1.86M
USD
Active NON-SBIR/STTR RPGS
Predicting fetal growth early in pregnancy with non-invasive MRI: Validation in a preclinical model
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... University of South Australia Australia 2024 – 2026

Project Summary Nearly 50% of all pregnancies complicated by fetal growth restriction (FGR) go undetected until after birth, despite improvements in obstetric imaging and managemen...

$2.95M
USD
Active NON-SBIR/STTR RPGS
Quantitative Hydrophobicity Sensor to Probe the Dynamics of Biomolecular Condensates
NATIONAL INSTITUTE ON DRUG ABUSE Johns Hopkins University United States 2024 – 2026

PROJECT SUMMARY Many important cellular processes are regulated through the formation and dissolution of the biomolecular condensates via liquid-liquid phase separation (LLPS). LLP...

$2.16M
USD
Active NON-SBIR/STTR RPGS
Fairness in Practice: Defining and Implementing Diversity & Representation in AI datasets for Healthcare
NATIONAL HUMAN GENOME RESEARCH INSTITUTE Stanford University United States 2024 – 2027

There is widespread agreement that fairness—ensuring equitable performance across similarly situated individuals and across groups—is a fundamental principle for ethical developmen...

$5M
USD
Active NON-SBIR/STTR RPGS
Mayo Clinic Consortium for Gut Brain Communication in Parkinson's Disease
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Mayo Clinic Rochester United States 2024 – 2029

PROJECT SUMMARY Gastrointestinal (GI) symptoms, especially constipation, affect >50% of persons with PD (PwPD). However, these concepts are exclusively based on tertiary care st...

$4.84M
USD