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606,025 grants found
Showing 25,721 – 25,740 of 606,025 grants
The State Alzheimer's Research Support Center (StARS)
Project Summary/Abstract-Overall Coordinated and integrated care programs for individuals with Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) and...
Admin Core - The State Alzheimer's Research Support Center (StARS)
Project Summary/Abstract-Administrative and Dissemination Core Establishment of an experienced, well-integrated, and collaborative Administrative and Dissemination Core is critical...
Partnership Core - The State Alzheimer's Research Support Center (StARS)
Project Summary/Abstract-Partnership and Engagement Core States across the U.S. have important data that could be used to improve care coordination, transitions, and health equity...
Research Core- The State Alzheimer's Research Support Center (StARS)
Project Summary/Abstract-Research/Pilot Core Multiple and interacting state-level policy and contextual factors influence the structure, processes, implementation, and outcomes of...
Data Core - The State Alzheimer's Research Support Center (StARS)
Project Summary/Abstract-Data Core State policymakers have made large investments in programs to support people with Alzheimer’s disease and Alzheimer’s disease-related dementia (A...
Race & Place: The Impacts of Racial Inequality on Substance Use and HIV Outcomes in Los Angeles
ABSTRACT It is well established that racial disparities in HIV care outcomes and use of substances among sexual minority men (SMM) of color persist because of structural racism in...
A Digital Toolkit to Address Intimate Partner Violence in Opioid Use Disorder
PROJECT SUMMARY/ABSTRACT Intimate partner violence (IPV), posttraumatic stress disorder (PTSD), and opioid use disorder (OUD) are highly co-occurring conditions. Up to 94% of indiv...
Use of DVC® systems to acquire and remotely view data for improved monitoring of animal models and their environment.
ABSTRACT This application requests funds to acquire specialized laboratory mouse housing systems- Digital Ventilated Caging (DVC) designed to initiate a new generation of husbandry...
Antibody targeting of the virome
PROJECT ABSTRACT While the microbiota has emerged as an important aspect of mammalian health, the vast majority of current studies have focused on the bacterial component of the mi...
Cell Type-Specific Alternative polyadenylation of mRNA in Alzheimer's disease
Project summary Alzheimer’s disease (AD) is the most common, slowly progressing neurodegenerative disease, resulting in de- mentia and eventually death. More than six million Ameri...
Preoperative Risk Prediction of Postoperative Complications for Elective Cardiac Surgery using At-home Smartphone Dynamometry
Project Summary/Abstract Surgical complication represents one of the biggest factors impacting quality of care and is one of the major burdens on the healthcare system. There are 4...
Development of 1,4-Benzodioxane Derivatives as F-18 PET Radiotracers for Alpha-2C Adrenergic Receptors and Their Preclinical Evaluations
PROJECT SUMMARY Millions of middle-aged and seniors in the United States maintain their blood pressure and prevent cardiovascular emergencies by taking - and -blockers daily. The...
Alzheimer's Disease (AD) and Vascular Brain Injury- related changes in longitudinal Magnetic Resonance Imaging associated with Intraindividual Cognitive Variability in Aging American Indians.
Project Summary/ Abstract American Indians are at higher risk for Alzheimer’s disease and Alzheimer’s disease related dementia (AD/ADRD) compared to the general population, yet dem...
Rapid In Vivo Screening of Combination Gene Therapies for Axonal Regeneration after Spinal Cord Injury
Project Summary/Abstract (max: 30 line limit) Adult neurons in the central nervous system fail to regenerate after spinal cord injury (SCI). Large-scale screens performed in vitro...
Development of a novel intracellular targeting nanobody that blocks Cx43-mediated pathological proliferation
|| Project Summary This R21 is in response to FOA PA-20-195/ NOT-HL-21-024: development of new ideas and first-generation prototypes for therapeutics and nanotechnologies as applie...
Feasibility and reproducibility of hyperpolarized 13C pyruvate human brain imaging on a new MRI scanner platform
PROJECT SUMMARY / ABSTRACT Hyperpolarized (HP) 13C pyruvate MRI is an emerging imaging modality that provides unique access to glucose metabolism in the brain, a pathway that is im...
Non-invasive abdominal fetal electroencephalography for fetal assessment
ABSTRACT Every year in the United States, over 35,000 newborns suffer from neurologic injury at the time of birth due to hypoxia. Despite widespread use of cardiac external fetal m...
Long-term Effects of a household Air Pollution intervention: Follow-up of a randomized controlled trial
SUMMARY Project Title: Long-term Effects of a household Air Pollution intervention: Follow-up of a randomized controlled trial Globally, nearly 3 billion people are exposed to hous...
Role of Sex in Immune Stromal cell Interactions driving cardiovascular lesions in Kawasaki Disease vasculitis
PROJECT ABSTRACT Kawasaki disease (KD), an acute febrile illness and systemic vasculitis of unknown etiology, is the leading cause of acquired heart disease among children in the U...
Role of Epigenetic Regulator SIN3a in Pulmonary Endothelial Cells
PROJECT SUMMARY Pulmonary arterial hypertension (PAH), a deadly cardiopulmonary disease that develops following a genetic or environmental insult, is characterized by pulmonary end...