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606,025 grants found
Showing 24,401 – 24,420 of 606,025 grants
Functional Interrogation of Type 2 Diabetes-associated Genetic Network
Abstract. Type 2 diabetes (T2D) is a polygenetic disease marked by impaired insulin secretion in pancreatic islet cells. Although genome-wide association studies (GWAS) have identi...
ISES 2024 Annual Meeting
Abstract The International Society of Exposure Science (ISES) is the premier international society devoted to bringing the full value of exposure science to research and decision-m...
Sustaining Home Palliative Care for Patients with Heart Failure (HF) and Their Family Caregivers in Rural Appalachia: A Mixed Methods Randomized Clinical Trial (RCT)
Project Summary Heart failure (HF) is the leading cause of mortality, morbidity, and rehospitalizations in Appalachia. Rural areas have the highest HF mortality rates. West Virgini...
Decoding FTIR-based multimodal imaging for risk assessment of precancerous oral lesions
PROJECT SUMMARY/ABSTRACT Successful treatment and management of oral mucosal lesions depend on a definitive, accurate, and timely diagnosis. Oral squamous cell carcinoma (OSCC) is...
Enhancing Diversity in Genomics Education and Research (EDGER)
PROJECT SUMMARY / ABSTRACT The proposed project entitled Enhancing Diversity in Genomics Education and Research (EDGER), submitted to the Initiative to Maximize Research Education...
Improving Measurement and Documentation of Long-term Neighborhood Change and Racial Segregation
PROJECT SUMMARY/ABSTRACT This is a study of neighborhood racial change and its impacts on trends in Black-white segregation over a multi-decade time span. It will provide much new...
Leveraging youth sports practices to increase physical activity among racial and ethnic minority mothers
Project Summary Women with racial and ethnic minority identities, specifically Hispanic and Black women exhibit suboptimal physical activity-related behaviors and are disproportion...
Gain-sensitive cochlear microphonics - a diagnostic test of functional and physiological effects of sensory hearing loss
PROJECT SUMMARY According to the Centers for Disease Control, hearing loss is the third most common chronic physical condition in the US, surpassing diabetes, and cancer in prevale...
Efficacy of Novel Melanocortin and Gut-peptide Dual Agonists for Childhood Obesity Treatment
SUMMARY The high prevalence of pediatric obesity requires new anti-obesity agents with increased efficacy, safety, and tolerance. Recent treatments based on endogenous gut peptides...
BMAL1 Circadian Clock Complexes from Mammalian Brain
Project Summary The circadian clock is an endogenous ~24-hour oscillator that drives daily rhythms of biological processes. In mammals, circadian clocks are found in the brain and...
Bioactivity of CAR T cells secreting T cell engager-anitbodies in humans with glioblastoma
PROJECT SUMMARY Glioblastoma (GBM) is a deadly brain tumor with limited treatment options. We have developed a promising new treatment for GBM using chimeric antigen receptor (CAR)...
Reducing falls with Varenicline in Hypocholinergic Parkinson disease
Falls are a major problem for people with Parkinson disease (PD).Falls and their sequelae are the leading cause of hospitalizations, precipitate institutionalization, and increase...
Multiplex Ultrasound Imaging for the Detection of Head and Neck Lymph Node Micrometastases
Project Summary Determining whether a tumor has spread to the regional lymph nodes is critical for staging and treatment planning for several types of cancer, including cancers of...
Video Inspired Discussions about Ethical Outcomes in Pediatrics (VIDEO-PEDS)
Parents of children with cancer often face complicated decision making throughout their child’s illness. Goals-of-care (GOC) interventions help patients, their families, and clinic...
Research and Engagement for Action on Climate and Health (REACH) Center
PROJECT SUMMARY - OVERALL The mission of the Research and Engagement for Action on Climate and Health (REACH) Center is to bridge big data to climate solutions that advance health...
REACH Center Administrative Core
PROJECT SUMMARY - ADMINISTRATIVE CORE The Administrative Core aims to promote research using big data to explore health-protective and equitable climate solutions through funding a...
REACH Center Research Project 1
SUMMARY – RESEARCH PROJECT 1: Transportation, Health, and Equity: A Community-Centered Study of Road Pricing in Washington, D.C. On-road vehicle emissions are the top contributor t...
REACH Center Research Project 2
SUMMARY - RESEARCH PROJECT 2: Landscape fire PM2.5, air conditioning, and mortality among dialysis patients Patients with end-stage renal disease (ESRD) would benefit from more kno...
REACH Center Developmental Core
PROJECT SUMMARY - DEVELOPMENTAL CORE The Developmental Core aims to provide pilot funding, networking, and educational and training opportunities to develop a multidisciplinary, co...
REACH Center Community Engagement Core
PROJECT SUMMARY - COMMUNITY ENGAGEMENT CORE The REACH Center Community Engagement Core will develop and apply strategies for catalyzing the co- creation of REACH Center climate and...