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606,025 grants found
Showing 35,961 – 35,980 of 606,025 grants
Advancing novel therapeutics and translational science to close the survivorship gap in pediatric, adolescent and young adult (AYA) lymphoma
PROJECT SUMMARY/ABSTRACT: Hodgkin Lymphoma (HL) has its first incidence peak in the adolescent and young adults (AYA) years. Despite the success of chemotherapy and radiation in yo...
Genetic and genomic influences on human milk composition and impacts on infant health
Human milk is recommended as the exclusive mode of feeding for infants, but the factors influencing the hundreds of nutritive and bioactive factors in milk and their functions in t...
Natural Phenolic Compounds against Oral Candidiasis (OC)
Contact PD/PI: MYLONAKIS, ELEFTHERIOS PROJECT SUMMARY Despite the availability of anti-retroviral therapy, oral candidiasis caused by the overgrowth of Candida spp. is the most fre...
Synergizing neutralization and non-neutralization antibody targets at the HIV/SIV viral spike apex
Project Summary An HIV vaccine remains a critical and as yet unrealized asset in the 40-year fight against the HIV/AIDS pandemic. New insights towards achieving vaccine protection...
Sequential Strategies to Reach and Reengage Individuals after Lapses from HIV Care in Zambia
ABSTRACT Treatment lapses remain one of the most enduring challenges to viral suppression in Africa. These individuals have higher rates of viremia (~70%), morbidity, and mortality...
miRNA profiling for monitoring and adjustment of immunosuppression in liver transplant recipients
Abstract Immunosuppression management follows standard protocol that is aimed at predetermined drug levels, with minimal adjustments over the lifetime of the recipient. While succe...
Spore germination pathway in Clostridioides difficile and its pharmacological intervention
ABSTRACT Clostridioides difficile is an anaerobic Gram-positive bacterium that colonizes the gut of patients treated with broad-spectrum antibiotics. A challenge in treating C. dif...
Unraveling the Role of p53 in Endothelium Homeostasis after Ionizing Radiation Exposure
Project summary Radiation therapy is an important component of cancer treatments, yet its usage has been hampered due to side effects to normal tissue. The current K99/R00 project...
Immigration Policies, Dietary Acculturation, and Childhood Obesity.
PROJECT SUMMARY One in four children in the United States (US) has at least one immigrant parent—more than a third of whom came to the US from Mexico more than any other country of...
Project EAGER: Enabling Access to Genomics Experience and Research
Project Summary Project EAGER is an ambitious collaborative initiative between California State University, Fullerton (CSUF) and the University of California, Berkeley (UCB) that w...
Identification of predictive biomarkers for severe acute leptospirosis and its long-term sequelae
Leptospirosis is a potentially life-threatening zoonosis with protean manifestations and a leading cause of acute febrile illness (AFI) in the tropics. The acute phase of leptospir...
Development of a hamster model for hepatitis B virus infection
PROJECT SUMMARY Hepatitis B virus (HBV) has infected more than one-third of the world’s population and that almost 296 million people are currently living with chronic infection in...
Washington University ACCERT center
Project Summary (Abstract) Goal: The overall goal of the WashU ACCERT is to advance cancer control equity through community - engaged multilevel research interventions that address...
Administrative Core
PROJECT SUMMARY – ADMINISTRATIVE CORE The Administrative Core will provide the structure for effective and efficient operation and maintenance of the Washington University Advancin...
Research Measures, Methods and Data Management Core
Project Summary- Research Methods, Measures, and Data Management Core The Research Methods, Measures, and Data Management (RMMDM) Core will advance the goal of the WashU-ACCERT cen...
Social Determinants of Health Research Project
Project Summary- Social Determinants of Health Multilevel Intervention Financial toxicity –hardships caused by the costs of cancer treatment– are common and have substantial impact...
Community Responsive Research Program
The overall goal of WashU-ACCERT is to advance cancer control equity through community-engaged multi- level research that addresses the impact of social determinants of health on c...
New Jersey Biomed-Bridge (NJBB) Scholars Program: Supporting Central NJ Community College Students in their Transition to Biomedical Research Pathways at The College of New Jersey
PROJECT SUMMARY The College of New Jersey (TCNJ) proposes to establish a Bridges to the Baccalaureate program in partnership with two local associate's degree granting communi...
Neonatal, Lactation, and Child Health Outcomes Following RSV Vaccination During Pregnancy
PROJECT SUMMARY Respiratory Syncytial Virus (RSV) can cause severe illness in young children and is the leading cause of infant hospitalization in the United States. Prenatal RSV p...
Defining multifunctional roles for proteins in development and disease
Project Summary This proposal for the NIGMS R35 Early-Stage Investigator award seeks to support my laboratory’s overall mission of determining multifunctional roles for proteins in...