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606,025 grants found
Showing 35,041 – 35,060 of 606,025 grants
Racial and ethnic disparities in patient outcomes and intra-arrest resuscitation practices for in-hospital cardiac arrest
ABSTRACT The overarching goal of this R21 grant proposal is to evaluate racial and ethnic disparities in patient outcomes, racial and ethnic differences in the three key intra-arre...
Promoting Wellness among Native Americans in Urban Areas
Modified Project Summary/Abstract SectionThe Montana Consortium for Urban Indian Health, a non-profit dedicated to technical and educational support for the Urban Indian Organizati...
Improving screening and access to treatment for depression in care partners of people living with dementia
Depression affects up to 34% of care partners (CP) of people living with Alzheimer’s disease/Alzheimer’s disease-related dementia (PLWD) each year and despite the expansion of trea...
Cyst induction and growth in ADPKD
Abstract: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is one of the world’s most common life-threatening genetic diseases. Mutations in the genes PKD1 and PKD2 account for...
EQUITY IN ACCESS TO ALZHEIMER'S DISEASE PHARMACOLOGIC TREATMENT FOR AFRICAN AMERICAN AND WHITE PATIENTS IN ALABAMA A MIXED METHODS STUDY TO INFORM RECOMMENDATIONS EquAAL
PROJECT SUMMARY New disease modifying drugs, like lecanemab, if used equitably across populations disproportionately affected byAlzheimer’s disease (AD), like African Americans (AA...
USC Facebase IV Craniofacial Development and Dysmorpholoy Data Management and Integration Hub (FaceBase IV))
PROJECT ABSTRACT Dental, Oral and Craniofacial health (DOC) plays a significant factor in the overall well-being of the population. About half of all birth defects are associated w...
Novel Therapeutic for Kidney Failure: A Modified, Water-Soluble Orally-Active Caveolin-1 Scaffolding Domain Peptide with Improved Characteristics for Drug Development
Abstract Our long-term objective is to fill the unmet need for treatments for chronic kidney disease (CKD). Caveolin-1 is a promising therapeutic target in fibrotic diseases. The p...
Development of a novel therapeutic platform for smoking cessation and nicotine de-addiction
PROJECT SUMMARY / ABSTRACT Smoking is the leading cause of preventable disease and death in the U.S. As of 2021, over 30 million U.S. adults reported that they currently smoked cig...
A Novel Blood Test for Early Diagnosis of Frontotemporal Lobar Degeneration
Project Summary Our objective is to develop a blood-based diagnostic for early diagnosis and classification of Frontotemporal Lobar Degeneration (FTD). FTD is a common presenile de...
Preclinical Studies to Develop an Eya2 Tyr Phosphatase Inhibitor as a Novel Medulloblastoma Therapeutic
Medulloblastoma (MB) is the most common malignant brain tumor in children. For decades, there have not been significant advances in the treatment for MB, which still includes surge...
Small Molecule PAR1 Ligands for the Treatment of MASH
PROJECT SUMMARY Metabolic dysfunction-associated steatohepatitis (MASH, formerly NASH) is a liver disease characterized by the unnatural accumulation of lipids within hepatic cells...
Breath aerosol capture by electric field concentration
Project Summary This proposed project is aimed at developing a method for capturing and concentrating exhaled breath aerosols by electrostatically charging them and collecting them...
The Chiron Project: Using Virtual Reality to Prevent Substance Use Disorder in Healthcare Workers Facing Burnout
PROJECT Summary: The Chiron Project: Using Virtual Reality to Prevent Substance Use Disorder in Healthcare Workers Facing Burnout Stress and burnout at the workplace are associated...
SIV reservoirs dynamics during aging
Abstract The advancement of combinational antiretroviral therapy (cART) converts the life of people living with HIV (PLWH) to manageable diseases. However, due to the persistence o...
HIV-Associated Lung Disease: The Role of Nasal Mucosal Immunity and Microbiome
PROJECT SUMMARY/ABSTRACT People living with HIV (PLWH) are at heightened risk for chronic lung diseases. The mechanisms underlying this risk are poorly understood. Viral infections...
Activity-based Sensor Peptides for Direct, High-throughput, and Kinetic Quantitation of Oncogenic Protein Kinases in Unfractionated Cell and Tissue Samples
PROJECT SUMMARY 30 lines Protein kinases catalyze selective and timely protein phosphorylation and are essential for the normal function of all cells. Unregulated kinase activity i...
Revolutionizing Nicotine Vaping and Electronic Nicotine Delivery Systems Addiction Treatment through Innovative E-Vape Administration of Cytisine to Enhance Patient Adherence and Treatment Completion.
ABSTRACT Nicotine addiction is a persistent public health challenge, and smoking remains the leading cause of preventable disease and death in the United States. As of 2021, an est...
The generation, maintenance, and function of extrachromosomal DNA in a divergent eukaryote
Extrachromosomal DNA (ecDNA) is DNA that exists and functions separately from the main genome. In the malaria parasite, ecDNA is circular, unlike the linear chromosomes. Some ecDNA...
Graduate Research Fellowship Program (GRFP)
The National Science Foundation (NSF) Graduate Research Fellowship Program (GRFP) is a highly competitive, federal fellowship program. GRFP helps ensure the vitality and diversity...
SaTC: EDU: Augmenting Cybersecurity Education in Mobile Health (mHealth) Through Curriculum and Experimental Platform Development
Mobile health (mHealth) is a rapidly growing field that utilizes mobile devices like smartphones and wearables to provide healthcare services and information. While mHealth has the...