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606,025 grants found
Showing 33,861 – 33,880 of 606,025 grants
A Service User Informed Study of Certified Community Behavioral Health Center (CCBHC) Implementation and Impact in New York State
This is a service-user informed mixed-methods study of the implementation and impacts of the Certified Community Behavioral Health Clinic (CCBHC) program in New York State. CCBHCs...
Efficacy of a Smartphone-based Just-in-Time Adaptive Intervention to ReduceDrinking among Adults Experiencing Homelessness
PROJECT SUMMARY/ABSTRACT Approximately 1 out of every 3 adults experiencing homelessness has a current alcohol use disorder (AUD). Alcohol use plays a central role in increased mor...
Evaluating Telehealth Delivery of Brief Alcohol Screening and Intervention for College Students
Project Summary/Abstract The proposed research study will test the efficacy of a telehealth version of the Brief Alcohol Screening and Intervention for College Students (BASICS), w...
BDNF in the ventral hippocampus and the acute and chronic actions of alcohol
MODIFIED SPECIFIC AIMSAlcohol has been consumed by humans for more than 4000-years. Luckily, approximately 85%-90% of individuals who consume alcohol socially never develop alcohol...
Intrinsic transcriptional programs for regeneration of serotonergicconnectivity
Permanent disabilities following axonal injuries result from the failure of injured axons to regenerate and rebuild functional connections.Controlling axon regeneration is highly r...
Novel mechanisms of HIV-associated pulmonary vascular disease
PROJECT SUMMARY Thanks to the advent of combination antiretroviral therapy (cART), life expectancy has dramatically increased in people with HIV (PWH) and the spectrum of diseases...
Rifapentine in High Doses in Pregnancy with TB (Radiant-Moms) study
SUMMARY The risk of tuberculosis (TB) is twice as high during and immediately after pregnancy than any other time in a person’s life, and pregnant people with TB who are co-infecte...
Targeting the HIV-1 reservoir at cART initiation with CD4-mimetic interventions
Summary Combination antiretroviral therapy (cART) fails to eliminate HIV-1 persisting in reservoirs or prevent long-term complications in people living with HIV (PLWH); therapy int...
Continuing to Support and Enhance an Integrated Food Safety System Through Implementation of Program Standards, Data Sharing, Collaboration, and State Training and Equipment Grants.
AFDO 2024 Alliance to Support the Activities of the Integrated Food Safety System (IFSS), including the Grade A Milk Safety and National Shellfish Sanitation Programs Application:...
Optimization of novel inhibitors of human cytomegalovirus
Summary: Human cytomegalovirus (CMV) is a β-herpes virus with high seroprevalence rates of 60-90% within the population that can spread through bodily fluids, organ transplants, an...
A Tunable Nanophage Platform for Vaccine Development
PROJECT SUMMARY Newly emerging and long-standing infectious challenges, including arboviruses, Ebola virus and pandemic coronaviruses (CoVs), among others, pose serious public heal...
Off-resonant parametric control over THz collective modes in correlated materials: Complex driving protocols, non-equilibrium correlated states and applications.
Currently, light induced states of matter focus the attention of many researchers in condensed matter physics.An important limitation at the moment is the lack of efficient technol...
Vehicledesign to reduce weight material and C02
Purpose and goal:The primary goal is to adapt the STILFOLD technology to create a new concept for an existing car part made from multiple steel sheets in different shapes and sizes...
Continued Clinical Development of a Novel Pleural and Tracheal Sealant
PROJECT ABSTRACT A range of lung diseases and critical illnesses, including complications of mechanical ventilation, as well as trauma can result in air leak from the lung (pneumot...
Role of Beta Spectrin and Smad in Alcohol-Induced Liver and GI Cell Proliferation
PROJECT SUMMARY Alcohol-related liver disease (ALD) and nonalcoholic steatohepatitis (NASH) are two reasons Americans mostly require a liver transplant. Furthermore, aldehyde dehyd...
Mycobacterium avium complex pulmonary infection: immunologic and transcriptomic signatures of disease and treatment response
PROJECT SUMMARY/ABSTRACT We seek to define immunologic and transcriptomic signatures of Mycobacterium avium complex (MAC) pulmonary disease and microbiologic treatment response. No...
DNA transduction in intestinal microbiomes and the spread of pathogenicity traits
Project Summary Horizontal gene transfer (HGT) is a driver of rapid evolution and adaptation in microbial communities. HGT spreads genes among and between bacterial species and is...
Deconstructing antiseizure mechanisms of anterior thalamic nucleus electrical stimulation
PROJECT SUMMARY/ABSTRACT Epilepsy is one of the most prevalent neurological disorders. Patients with epilepsy experience abnormal brain activity causing seizures or periods of unus...
Mechanisms of Mucosal and Systemic Immunity to Vaccination and Infection with Enteric Pathogens in Children and Adults
Overall - Abstract Enteric bacterial infections are a significant global health concern, particularly in developing nations, where they disproportionately affect children. These di...
Administrative Core
Enteric Cooperative Centers on Human Immunology (Enteric CCHI) University of Maryland, Baltimore Enteric CCHI Administrative Core ABSTRACT The Administrative Core for the Enteric C...