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606,025 grants found
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Collaborative Research: Nonlocal Second Moment Upper Ocean Boundary Layer Modeling
The upper ocean boundary layer (OSBL) controls the vertical transfer of heat, mass, and momentum from the atmosphere to ocean interior, affecting water properties and influencing c...
Manufacture Biomimetic Spatially Varying Fiber Arrangement in Soft Fiber Reinforce Composites Using Aerodynamic Fiber Deposition
Biological tissues, such as skin, muscle, cartilage, and bone are composed of nano/microfibers embedded in a matrix. The fiber arrangement varies over complex tissue geometries to...
Postdoctoral Fellowship: AAPF: A Multi-Decade Statistical Analysis of Sagittarius A*'s Total Intensity and Polarimetric Variability at Radio and Submillimeter Frequencies
Joseph Michail is awarded an NSF Astronomy and Astrophysics Fellowship to carry out a program of research and education at the Harvard-Smithsonian Center for Astrophysics. Michail...
SHF: Small: High-Performance Incremental Spectral Algorithms for Efficient Modeling and Simulation of Large-Scale Integrated Circuits
Modern integrated circuits (ICs) integrate billions of transistors into a single chip. Even key subsystems such as clock distribution networks, power delivery networks (PDNs), embe...
CAREER: Declarative AI Data Cleaning with Guarantees
The rise of powerful and data-hungry artificial intelligence (AI) models has shifted the focus of research from model-centric AI to data-centric AI, since the quality of machine le...
CAREER: Modeling the Evolution of Massive Galaxies with Enzo-E
The past few decades have seen tremendous advances in our understanding of galaxy formation and evolution using both observations and detailed computer simulations. However, many k...
Collaborative Research: EDGE CMT: Linking genomic variation to complex floral trait adaptation across a species boundary
A fundamental challenge in biology is to understand how DNA differences between individuals determine trait differences, particularly those trait differences that define species. T...
An Isotope-Enabled Data Assimilation System for the Last Millennium over South America
The scientific objectives of this project are to: i) quantify the spatiotemporal characteristics of the South American summer monsoon (SASM) and its relationship with the Atlantic...
Collaborative Research: Investigating human dental senescence with a mechanically simulated model of dental wear progression
Dental wear is a common but poorly understood process that progresses over the lifespan of an individual. In time, dental wear leads to dental senescence and significant dental cos...
Collaborative Research: Bridging short and long time scales in global plate tectonics through solver adaptivity
The underlying geophysical connections linking great earthquakes with plate tectonics will be addressed using sophisticated models. These seismic events are the largest earthquakes...
SBIR Phase I: Bioengineered Next-Generation Tympanostomy Tubes to Improve Patient Outcomes
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is the advancement of implantable medical devices through innovative use o...
The Influence of Aging on Plasma Cell Function and Bone Marrow Competition
Abstract: Aging represents a prominent risk factor for infection-related mortality. This heightened susceptibility to infection is closely associated to the attenuation of both str...
Improving Brief Assessment of Suicidal Thoughts and Behaviors in Youth: An Engaged, Stakeholder-Informed Approach to Measure Development, Testing, and Implementation
PROJECT SUMMARY/ABSTRACT Suicide is the third leading cause of death among youth ages 15-24 in the United States. Accurate assessment of suicidal thoughts and behaviors (STBs) is c...
Cardiac troponin i3 kinase in viral myocarditis
ABSTRACT Myocarditis is a leading cause of heart failure and sudden cardiac death, but many cases of myocarditis follow a benign course. It is unknown what factors control this var...
Nasal uptake of polystyrene nanoplastics into the murine central nervous system
Project Abstract: Air pollutants such as nanoplastics have been identified to increase risks for neurodegenerative diseases such as Alzheimer’s disease and related dementias (ADRDs...
The role of lymphatics in cholestatic liver disease
SUMMARY Cholestatic liver diseases such as primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are autoimmune liver diseases with limited treatment options....
Associations of GLP-1-related genotypes with appetitive traits, food cue reactivity, and prospective weight gain in pre-adolescence
Project Summary Obesity is a chronic disease that is increasingly common, resistant to treatment, and responsible for a broad range of medical comorbidities and excess mortality. P...
Homeostatic control of intestinal stem cell renewal by two transcriptional coactivators
PROJECT SUMMARY Mechanisms that integrate local and systemic cues to precisely regulate stem-cell based tissue renewal remain unclear, particularly in the rapidly cycling gastroint...
Elucidating the molecular function of Kaposi's sarcoma-associated herpesvirus packaging accessory protein ORF68
Project Summary The standard treatments against other human herpesviruses have limited efficacy against Kaposi’s sarcoma- associated herpesvirus (KSHV). A mechanistic understanding...
Identifying the Neurophysiological Phenotypes that Contribute to Alcohol-Related Blackout Susceptibility
PROJECT SUMMARY Alcohol-related blackout has traditionally been considered a warning sign of the development of an Alcohol Use Disorder (AUD). However, not all individuals who bing...