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Showing 29,74129,760 of 606,025 grants

Active TRAINING, INSTITUTIONAL
Genetic and Environmental basis of Cancer Risk and Disparities (GECaRD)
NATIONAL CANCER INSTITUTE Stanford University United States 2024 – 2029

Abstract This proposal is for a new T32 predoctoral program to train the next generation of multi-disciplinary cancer researchers with the expertise to unravel the complexity of fa...

$1.66M
USD
Active TRAINING, INSTITUTIONAL
Alzheimer's Disease Big Data to Biology Training Program (ADBDB-TP)
NATIONAL INSTITUTE ON AGING Emory University United States 2024 – 2029

ABSTRACT As the most common dementia, Alzheimer's disease (AD) exacts an immense personal, societal, and economic toll. Though we largely conceptualize AD as a disease of agin...

$5.86M
USD
Completed NON-SBIR/STTR RPGS
Exploring the differential spreading of distinct pathological conformers of AD/LBD-related proteins by combining mathematical modeling and functional study
NATIONAL INSTITUTE ON AGING University of California, San Francisco United States 2024 – 2026

Project Summary Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) are characterized by the deposition of pathological proteins, such as pathological...

$2.22M
USD
Active NON-SBIR/STTR RPGS
EDGE CMT: Neural cell type evolution in insect retinas
NATIONAL HUMAN GENOME RESEARCH INSTITUTE University of California, San Diego United States 2024 – 2028

PROJECT SUMMARY (See instructions): Overview: Animal genomes provide instructions for producing an amazing diversity of cell types during development, perhaps especially in the bra...

$3.28M
USD
Active OTHER RESEARCH-RELATED
Village-Integrated Eye Worker Trial II (VIEW II) Extension
NATIONAL EYE INSTITUTE University of California, San Francisco United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT The World Health Organization estimates that 80% of blindness worldwide is avoidable. However, in resource-limited settings progressive eye diseases such a...

$14.49M
USD
Active TRAINING, INSTITUTIONAL
LYMphatics in Pathology and Health (LYMPH)
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Texas A&M University Health Science Ctr United States 2024 – 2029

Although various research institutions and clinics in the United States successfully train graduate students in cardiovascular biology, specific training in lymphatic biology is la...

$894.4K
USD
Active NON-SBIR/STTR RPGS
Integrated PET+DBT for optimization of breast cancer therapy
NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOEN... University of Washington United States 2024 – 2029

Building on our previous work, we are proposing an innovative dual-mode breast cancer scanner combining positron emission tomography (PET) and x-ray tomosynthesis (XT). Patient-spe...

$7.08M
USD
Active RESEARCH CENTERS
Translational Research Program in Colorectal Cancer Disparities
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT – Overall Racial and ethnic disparities in colorectal cancer (CRC) are particularly pronounced in African American and Alaska Native people. These differen...

$25.76M
USD
Active RESEARCH CENTERS
Core A: Administrative Core
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT – Administrative Core (AC) In our currently active Translational Research Program in Colorectal Cancer Disparities (TRPCD) funded as a P20 SPORE planning g...

Active RESEARCH CENTERS
Project 1: Racial and ethnic differences in the intra-tumoral microbiome: Impact on colorectal cancer mortality and clinicopathologic correlates
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT of Project 1 Colorectal cancer (CRC) is one of the leading causes of cancer death, and it disproportionately impacts African American people whose CRC mort...

Active RESEARCH CENTERS
Project 2: Discovery and validation of novel molecular and immune predictors of colorectal cancer mortality and response to treatment in racially and ethnically diverse patient populations
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT Disparities in colorectal cancer (CRC) incidence and mortality are appreciable and continue to persist in the United States particularly among Alaska Nativ...

Active RESEARCH CENTERS
Project 3: Racial and ethnic differences in the intra-tumoral microbiome: Impact on colorectal cancer mortality and clinicopathologic correlates
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT Colorectal cancer (CRC) incidence and mortality vary greatly by race and ethnicity in the United States (US). Alaska Native people have among the highest r...

Active RESEARCH CENTERS
Project 4: Effect of Meal Timing during Cancer Treatment in Alaska Native Patients - A Randomized Clinical Trial
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT – Project 4 A promising strategy for reducing toxicity and improving the efficacy of anticancer treatments involves combining treatment with fasting regime...

Active RESEARCH CENTERS
Core B: Biospecimen and Pathology Core
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT of the Biospecimen and Pathology Core (BPC) The Biospecimen and Pathology Core (BPC) of the Translational Research Program in Colorectal Cancer Disparities...

Active RESEARCH CENTERS
Core C: Biostatistics and Bioinformatics Core
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT of the Biostatistics and Bioinformatics Core (BBC) The Translational Research Program in Colorectal Cancer Disparities (TRPCD) SPORE will utilize cutting-...

Active RESEARCH CENTERS
Developmental Research Project
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT of the Developmental Research Program (DRP) The Developmental Research Program (DRP) will provide key support to rapidly advance new ideas that have the po...

Active RESEARCH CENTERS
Career Enhancement Program
NATIONAL CANCER INSTITUTE Fred Hutchinson Cancer Center United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT of the Career Enhancement Program (CEP) Our Translational Research Program in Colorectal Cancer Disparities' (TRPCD) Career Enhancement Program is an...

Active RESEARCH CENTERS
Center for Genetics, Genomics, and Epigenetics of Substance Use Disorders in Outbred Rats
NATIONAL INSTITUTE ON DRUG ABUSE University of California, San Diego United States 2024 – 2029

Project Summary (Overall) The goal of this P30 application is to support the community of scientists who use outbred heterogeneous stock (HS) rats to understand the genetic basis o...

$14.23M
USD
Active RESEARCH CENTERS
Core A
NATIONAL INSTITUTE ON DRUG ABUSE University of California, San Diego United States 2024 – 2029

Project Summary/Abstract (Core A: Administrative Core) The Administrative Core will facilitate coordination among all other cores and supported grants. The purpose of this center i...

Active RESEARCH CENTERS
Core B
NATIONAL INSTITUTE ON DRUG ABUSE University of California, San Diego United States 2024 – 2029

Project Summary/Abstract (Core B: HS Breeding Core) The heterogeneous stock (HS) Breeding Core (PI: Dr. Leah Solberg Woods) will maintain an HS rat colony at the Wake Forest Univer...