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606,025 grants found
Showing 28,901 – 28,920 of 606,025 grants
Trace Elements (TE)
Project Summary/Abstract: Trace Elements The chemistry of inorganic elements is linked inextricably with the study of cancer. This is especially true for our catchment area, given...
Cancer Population Sciences (CPS)
Project Summary/Abstract: Cancer Population Sciences The Cancer Population Sciences (CPS) Program brings together 40 faculty, representing 12 departments at Dartmouth’s Geisel Scho...
Cancer Biology and Therapeutics (CBT)
Project Summary/Abstract: Cancer Biology and Therapeutics The Cancer Biology and Therapeutics (CBT) Program brings together 37 faculty, representing 12 departments at Dartmouth’s G...
Translational Engineering in Cancer (TEC)
Project Summary/Abstract: Translational Engineering in Cancer The Translational Engineering in Cancer (TEC) Program brings together 25 faculty, representing 12 departments at Dartm...
A lightweight robotic telerehabilitation device with integrated blood flow restriction for patients with musculoskeletal conditions
Project Summary/Abstract There are 2.5 million patients in the United States annually who receive knee surgeries, such as knee replacements and ligament repairs and as the populati...
Community Outreach and Engagement
Project Summary/Abstract: Community Outreach and Engagement The Dartmouth-Hitchcock Norris Cotton Cancer Center (NCCC) is unique among NCI-designated Cancer Centers as the only one...
Developmental Funds
Project Summary/Abstract: Developmental Funds The current request for CCSG funding is targeted to emerging opportunities at Dartmouth in active faculty recruitments, Members’ colla...
Leadership, Planning and Evaluation
Project Summary/Abstract: Leadership, Planning and Evaluation NCCC has an 11-member Senior Leadership team clearly aligned with Center-wide planning and evaluation responsibilities...
Synergistic contributions of cerebrovascular disease and neuroinflammation to Alzheimer's disease in adults with Down syndrome
PROJECT SUMMARY Down syndrome (DS) is considered a genetic form of Alzheimer’s disease (AD). Most adults with DS have AD pathology by age 40 and progress to dementia by 60-years ol...
Clinical Protocol and Data Management (CPDM)
Project Summary/Abstract: Clinical Protocol and Data Management The Office of Clinical Research (OCR) is the established office within the Norris Cotton Cancer Center (NCCC) which...
Protocol Review and Monitoring System (PRMS)
Project Summary/Abstract: Protocol Review and Monitoring System The Norris Cotton Cancer Center (NCCC) has established a process by which clinical trials/population science studies...
Elucidation of the mechanisms by which Ms4a genes regulate neurodegeneration in Alzheimer’s Disease and related disorders
Project Summary/Abstract Current therapeutic interventions for treating neurodegenerative disorders, including Alzheimer’s Disease (AD), frontotemporal dementia (FTD), multiple scl...
Project 4
Breast cancer is the most common invasive cancer among women worldwide and the second leading cause of cancer mortality in women.However, breast cancer is not a single disease, but...
Development of a Disposal Point-of-Care HIV Nucleic Acid Test
Rapid Diagnostic Assays for Self-Monitoring of Acute or Rebound HIV-1 Infection: The goal of this program is to develop low-cost, rapid diagnostic assays needed to enable untrained...
Enhanced intratympanic delivery of therapeutics to treat and prevent hearing loss using nanovesicles in the porcine model
PROJECT SUMMARY My long-term goal is to help develop and deliver regeneration therapeutics useful for the clinical treatment of hearing loss. Unfortunately, at this time there is n...
Producing Recombinant mRNA in Escherichia coli
PROJECT SUMMARY The success of mRNA-based vaccines and their modular technology have propelled RNA- based medicines from a relatively niche technology into the mainstream. As RNA-b...
Building Interdisciplinary Research Careers in Women's Health (K12) - Administrative Supplement
7. Project Summary/Abstract Duke University and North Carolina Central University (NCCU), a historically Black institution, are applying for additional support for Dr. Tarannum Jal...
In vivo chemical changes of contemporary polyethylene in TKA: implications for wear and osteolysis
This proposal addresses the unmet need that the mechanisms governing in vivo chemical changes of total knee arthroplasty (TKA) tibial liners are not known. Our objective is to dete...
Mid-sized GDNF Minics for Neural regeneration
Project Summary Repair of traumatic injuries relies upon glial cell line-derived neurotrophic factor (GDNF), and related extracellular cytokines collectively called GDNF family lig...
Post-GWAS Functional Genomics Analysis to Define Pathogenic Mechanisms for Pulmonary ArterialHypertension
PROJECT SUMMARY Pulmonary arterial hypertension (PAH) is an enigmatic and morbid disease where insights are emerging regarding genetic susceptibility to disease. Genome-wide Associ...