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606,025 grants found
Showing 27,341 – 27,360 of 606,025 grants
Cultural adaptation of a mobile caregiver intervention for Hispanic dementia caregivers
Project Summary Hispanics are the fastest growing minority population in the U.S., they are 1.5 times more likely to develop Alzheimer’s disease and related dementias (ADRD), and H...
Developing and Testing a Video-feedback Intervention to Promote Racial-Ethnic Socialization Competency in Latino/a/x Families
PROJECT SUMMARY/ABSTRACT Racial-ethnic discrimination impacts too many Latino/a/x youth and poses a significant threat to their health and well-being, increasing vulnerability for...
Association of DNA Methylation and Stress in Immigrants
PROJECT SUMMARY Immigrants experience significant health disparities which are exacerbated by a heavy stress burden which in turn affects the epigenetic profiles of the immune syst...
Molecular mechanisms of Kv1 channel localization at the axon initial segment
PROJECT SUMMARY As the site of action potential initiation, the axon initial segment (AIS) contains high densities of voltage-gated sodium (Nav) and potassium (Kv) channels that ge...
From Survival to Living Well: A Socioecological Approach to Understand Acquired Disability and Advance Health Equity in Rural Appalachia
ABSTRACT People with disabilities are significantly more likely to experience chronic conditions and are at risk of dying up to 20-years earlier than people without disabilities du...
The Role of Lymphatic Endothelial Cell- Expressed Sphingosine-1-Phosphate Receptor 1 on Immune Cell Trafficking and Response to Influenza Virus
ABSTRACT Lymphatic vessels are a critical component of the immune response to pathogens because they transport leukocytes carrying antigens to lymph nodes (LNs) to facilitate antig...
Broadening Biomedical Research Workforce Participation through Culturally Responsive Mentoring
PROJECT ABSTRACT Utilizing effective evidence- and asset-based approaches in mentorship are essential to improving the success of trainees from diverse backgrounds in STEMM and bio...
Gastrointestinal Tract XXI
Project summary/abstract This application requests partial support for a FASEB Scientific Research Conference entitled “Gastrointestinal Tract XXI: "Life, Death and Disease of...
Custom nanomaterials from modular synthetic proteins
Science and technology constantly strive to develop sustainable materials and processes. Biology is an extremely rich source of solutions to similar problems that bacteria, fungi,...
Leveraging HIV care infrastructure for implementation of context-adapted liver cancer comprehensive control strategies in Uganda: The LC3 Study
Project Summary: For >18-years, Makerere and Johns Hopkins universities have partnered in Uganda to characterize the epidemiology of hepatitis B (HBV) and HIV co-infection, defi...
Engineered Glioblastoma-specific T cells using Immunostimulatory Photothermal Nanoparticles
PROJECT SUMMARY The goal of this STTR Phase I application is to establish the feasibility of commercializing a personalized and multi-targeted adoptive T cell therapy (ATCT) for gl...
A tunable laser scanning system for rapid analysis of biopharmaceutical formulations
Project Summary The goal of this Direct to Phase II SBIR proposal is continue development of Nirrin’s proprietary tunable laser spectrometry system in preparation for commercializa...
#EverythingSucks: Understanding the bidirectional relations between vulnerability to internalizing symptoms in youth (13-20) and social mediacontent
Project summary The proposed research is a longitudinal study in adolescents aged 13-20-years old (N = 1,000) triangulating (1) ecological momentary assessment (EMA) with (2) concu...
Neural Substrates of Autism and ADHD: Reward Circuitry Connectivity and Individual Differences
PROJECT SUMMARY/ABSTRACT Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) exhibit significant clinical overlap, but the shared and distinct biolog...
Event-level Antecedents of Heavy Drinking Among Bisexual and Heterosexual Women with and without Histories of Sexual Assault
PROJECT SUMMARY Heavy drinking and sexual assault co-occur, and bisexual women are at elevated risk for both. Approximately 25% of bisexual women relative to 11% of heterosexual wo...
PURE-Climate: Identifying and Adapting to Climate Change as a Modifiable Risk Factor for Human Health
ABSTRACT Climate change is the largest global health challenge of the 21st century. Although direct and indirect effects of climate change threaten health worldwide, the impacts wi...
ENRICHED Study: Completion of Follow-up Assessments for Phase 1 and Prenatal and Neonatal Assessments for Phase 2
The Division of Population Health Research (DiPHR) at the Eunice Kennedy Shriver National Institute of Child Health and Human Development conducts studies focusing on child health...
NIDCD Clinical Trials Program (CTP)
The National Institutes of Health (NIH) is seeking to award a service contract to support the National Institute on Deafness and Other Communication Disorders (NIDCD) Clinical Tria...
Relationships between gestational diabetes subtypes and fetal growth and adiposity
Gestational diabetes (GDM), defined by new onset hyperglycaemia in pregnancy, affects ~14% of pregnancies worldwide, and the prevalence is increasing.Short term impact includes inc...
You snooze, you win: torpor as a model of resilience
When deprived of food, daily heterotherms such as mice enter torpor - a protective state of reduced body temperature, oxygen consumption, and heart rate akin to a brief hibernation...