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606,025 grants found
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Compounding extreme rainfall and heatwaves: how important are large scale dynamics in generating extreme floods?
Weather extremes carry immense importance for society due to their potential to endanger human lives and cause extensive economic damages.In Europe, heatwaves rank among the most d...
Cerebral microhemorrhages and gait abnormalities in aging
Project Summary/ Abstract The growing prevalence of multifocal cerebral microhemorrhages (CMHs), also known as "cerebral microbleeds," is a significant and newly recogniz...
TBC
TBC
MoDCons: Multi-Modal Microscopy of Doped Semiconductors
The development of efficient, low-cost, and durable doped semiconductors including photovoltaics, light-emitting diodes (LEDs) andtransistors will be central to the EU goal of reac...
Clinically-useful vehicles for in vivo delivery of mRNA to stem and progenitor cells
Abstract Rejuvenation Technologies Inc. (RTI) aims to expand the utility of our telomere extension biologic, telomerase (TERT) mRNA, and our world-leading lipid nanoparticle (LNP)...
Bioreactors to Replace Animal Testing in Bone Research
Our vision is to replace need for animal testing in bone research with lab-based bioreactor analyses of human tissue. The immediate benefit will be replaced animal burden for bone...
To be confirmed
To be confirmed
Identifying Successful Strategies of Specialist Palliative Care Implementation for People with Advanced Heart Failure
Project Summary Over 280,000 people die from advanced heart failure each year in the United States. This population experiences burdensome symptoms, frequent hospitalizations, and...
Cultural Adaption of Behavioral Activation and Therapeutic Exposure for Grief Among American Indian People
Project Summary/ Abstract Candidate: The overall goal of this K01 career development proposal is to provide me with the training experience needed to become a leader in health equi...
Acquisition of a BD High Throughput Sampler, Symphony A5 SE, to Promote Translational Discovery through Spectral Flow Cytometry
Project Summary Drexel University is a prestigious, highly diverse R1-level institution built upon a strong history of interdisciplinary collaborations across its many departments...
Molecular Targets Modulating Neuro COVID Sequelae Linked to Tauopathy
The COVID-19 pandemic caused by SARS-CoV-2 (CoV2) virus has left a large cohort of individuals suffering from ongoing neurological sequelae known as neuro-COVID. The condition invo...
Utilizing the NHANES-Linked Medicaid Data to Understand the Role of Preconception Lifestyle Factors on Pregnancy Outcomes
PROJECT SUMMARY Although lifestyle factors have been investigated for their potential to modify risk of adverse pregnancy outcomes, initiating interventions during pregnancy may no...
The Role of Biological Sex in the Self-renewal of B1 Cells into Old Age in Mice and Humans
Project Summary/Abstract By the year 2050 the WHO predicts there will be 2 billion people aged 60-years and over. As the population of aged individuals rises so will aging-associat...
Improving measurement of cancer registry completeness
PROJECT SUMMARY Surveillance for cancer incidence and mortality is crucial to cancer control and cancer research. Cancer registries are the basis for allocating public health resou...
Evaluating the disease modifying properties of dimethyl fumarate (DMF) for the prevention and treatment of pharmacoresistant epilepsy
ABSTRACT Progressive decline in seizure control and cognitive function, coupled with anxiety and depression are often consequences of epilepsy that negatively impact a patient’s ov...
Integrating genetic and circuit variation to identify genes involved in behaviors related to substance use disorder
PROJECT SUMMARY The goal of this proposal is to identify genes that affect behaviors associated with substance use disorders (SUD) using a novel mechanism-to-gene strategy. Standar...
Partnering with Pregnant and Postpartum People to Co-Create a Novel Intervention to Reduce Tobacco and Cannabis Use
1R01DA057946-01A1Enter the text here that is the new abstract information for your application. This section must be no longer than 30 lines of text.Prenatal tobacco use among non-...
Basolateral amygdala dopamine in addiction-related learning strategies
Project Summary Environmental stimuli (“cues” – sensory information such as sights, sounds, and smells) help organize reward seeking and decision making. In disease states like add...
Regulating dopamine transport through allosteric modulation - Functional and Behavioral Studies
The plasma-membrane monoamine transporters (MATs), including the serotonin (SERT), norepinephrine (NET) and dopamine (DAT) transporters, serve a pivotal role in limiting monoamine-...
An open road driving performance task to examine long-term medical marijuana use and prescription opioid positivity in adults 50 and older
PROJECT SUMMARY Medical marijuana is legal in 37 states and the District of Columbia, and use among adults 50 and older has more than doubled in the past decade, with exponential i...