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Investigating Suicide Risk and Protective Factors among Economically Disadvantaged, Preteen Black Youth
Suicide among Black preadolescents has increased rapidly over the last two decades, reaching unprecedented levels. While there have been substantive gains in knowledge related to t...
Health-associated oral bacteria as anti-cancer and immunomodulatory agents in oral cancer
PROJECT SUMMARY Oral squamous cell carcinoma (OSCC) exerts a significant clinical and financial burden worldwide. OSCC continues to have poor prognosis despite advances in treatmen...
Non-rotating nano-optic endoscope for 360 degree in vivo imaging
Endoscopic optical imaging has the potential for providing critical clinical imaging feedback for a variety of lumi- nal organs, with notable applications identified in the cardiov...
Assessment of Uterine Cervical Insufficiency using 4D Contrast-Enhanced Ultrasound
Cervical insufficiency (CI) describes the inability of the uterine cervix to retain a pregnancy in the absence of the signs and symptoms of clinical contractions, or labor, or both...
How Do OpenNotes Policies Affect Healthcare Disparities? A Computational Approach
Project Summary/Abstract The new OpenNotes rule in the United States enables all patients easy access to their medical records. The policy affords many benefits to patients such as...
Lateralization of posterior-parietal cortex contributions to motor learning
Project Summary: Motor learning is fundamental for humans to become proficient in daily activities, such as self-care, work, and leisure. Two fundamental components of motor learni...
Association between adverse maternal factors and neurodevelopmental outcomes among children in Kenya
ABSTRACT More than half of Kenyan children under 5-years (~4 million Kenyan children) will not reach their developmental potential, a pathway partly determined by modifiable matern...
Investigating SMARCE1 in Regulating Cohesin Activity, Chromatin Folding, and Gene Expression
PROJECT SUMMARY The cohesin complex mediates the hierarchical organization of the genome into chromatin loops and topologically associating domains (TADs) through a proposed model...
Next-generation nanoflow LC column technology to enable high sensitivity proteomics of limited samples
PROJECT SUMMARY Molecular analysis of limited biological and clinical samples is of high significance and growing interest, as observed from the exponentially increasing number of...
Anise Health: Culturally-Sensitive Digital Mental Health for Asian Americans
Abstract The 22 million Asian Americans (AAs) are up to 5 times more likely to drop out of mental health treatments prematurely and 50% more likely to report such treatment being i...
Phylodynamic mechanisms of HIV reservoir seeding and maintenance
PROJECT SUMMARY The HIV reservoir is a population of latently HIV infected cells that persists in people living with HIV on suppressive antiretroviral therapy (ART) and prevents cu...
The SUSTAIN 2 study - SUStained HIV Treatment for Adherence After Interruption in Care
PROJECT SUMMARY South Africa bears the brunt of the global HIV epidemic, with over one-fifth of the 37 million people living with HIV within its borders. While we have seen tremend...
Ethical Approaches to Informed Consent for Autonomous Robotic Assisted Surgery
PROJECT ABSTRACT Surgery is on the verge of a paradigm shift towards autonomous robot-assisted surgeries (RAS). Increasingly, RAS is incorporating artificial intelligence (AI) algo...
Control of Mammalian Craniofacial Morphogenesis by the ESCRT Machinery
Abstract Signaling molecules and their receptors rely on endo-lysosomal trafficking to prevent their accumulation on the plasma membrane, which would perturb craniofacial developme...
RNA localization in neural crest migratory protrusions
SUMMARY A fundamental question in developmental biology is how migratory cells initiate migration, move in a directed fashion towards their target, terminate migration and differen...
The Role of Brain-Oral-Microbiome Axis in Adverse Childhood Experiences-associated Dental Caries in Children
PROJECT SUMMARY/ABSTRACT Adverse childhood experiences (ACEs), traumatic experiences encountered during early life stages, can profoundly impact health and well-being into adulthoo...
Development of a Needle Free Microarray Patch for Delivery of a GLP-1 Receptor Agonist
Project Summary/Abstract Over 400 million adults worldwide are living with Type 2 diabetes (T2D). Despite significant advancements in effective treatments, T2D continues to rise at...
Addressing Disaster Displacement for Recovery with Equitable and Sustainable Systems (ADDRESS) of HIV Care in Puerto Rico
Project Abstract/Summary: Career Goal. My long-term career goals are: (1) to obtain and secure a full-time tenure track faculty appointment and (2) become an independently funded h...
Unified and fair multimodal representation learning for autoimmune diseases
ABSTRACT Autoimmune diseases affect 1 in 10 people. Commonly, patients needlessly suffer for years due to delays in diagnosis and referral delays to specialists. Systemic lupus ery...
SoS:B10:ldentifying and Encouraging Connections among Data Reuse, Scientific Innovation, and Scientific Careers
PROJECT SUMMARY {See instructions): This project has two main goals: measuring the impact of research data reuse on diversity and novelty, and identifying synergistic data-method-r...