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Showing 23,68123,700 of 606,025 grants

Active NON-SBIR/STTR RPGS
Nuestro Valor: Increasing healthier food access for rural Latino communities through a food retail intervention
NATIONAL INSTITUTE OF NURSING RESEARCH University of Washington United States 2024 – 2029

Project Abstract Diets low in fruits and vegetables are associated with chronic disease disparities for Latinos living in rural areas. Furthermore, in rural areas, structural and s...

$7.49M
USD
Active NON-SBIR/STTR RPGS
Dynamic Functional Mapping of Alzheimer's Spectrum and HIV-related Brain Dysfunction
NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND S... Father Flanagan'S Boys' Home United States 2024 – 2029

Project Summary/Abstract Mild cognitive impairment (MCI) remains a critical problem in patients infected with HIV, but it is also commonly seen in patients with diabetes, early Alz...

$7.89M
USD
Completed NON-SBIR/STTR RPGS
Longitudinal Impact of Fluoride on Neurodevelopment and Neuroimaging Outcomes During Childhood and Adolescence in the United States and Mexico
NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCE... University of Cincinnati United States 2024 – 2025

Exposure to fluoride is ubiquitous in many developed countries including the United States and Mexico due to fluoridation of water and salt, respectively. Several studies from Cana...

$6.4M
USD
Completed NON-SBIR/STTR RPGS
The Role of Residential Bioaerosol Exposure in Pulmonary Sarcoidosis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of Iowa United States 2024 – 2025

Summary/Abstract Sarcoidosis a rare systemic inflammatory disease with high morbidity and increasing mortality. Granulomatous inflammation affects the lungs in 90% of cases, with ~...

$7.52M
USD
Completed NON-SBIR/STTR RPGS
A framework for interpreting global effects of genetic variants contributing to disease risk
NATIONAL HUMAN GENOME RESEARCH INSTITUTE University of California, San Diego United States 2024 – 2025

Advances in next-generation sequencing are enhancing the routine detection of human genetic variants, particularly in clinical settings. Yet, the ability to interpret the functiona...

$7.57M
USD
Completed NON-SBIR/STTR RPGS
Alleviating antibiotic-induced microbiome dysfunction by quenching the microbial redox environment
NATIONAL CENTER FOR COMPLEMENTARY & INTEGRATIVE HE... Brown University United States 2024 – 2025

PROJECT SUMMARY Antibiotic-induced disruption (AID) of the gut microbiome can lead to severe conditions like C. diff colitis and may contribute to long-term health issues, includin...

$3.4M
USD
Completed OTHERS
All of Us Research Program Data and Research Center
OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEA... Vanderbilt University Medical Center United States 2024 – 2025

Project Summary/Abstract - The All of Us Research Program’s overarching goal is to transform our understanding of the factors that contribute to health and disease, and ultimately,...

$41.21M
USD
Completed NON-SBIR/STTR RPGS
Identifying and characterizing human pulmonary neuroendocrine stem cells and their diversity
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Stanford University United States 2024 – 2025

PROJECT SUMMARY Pulmonary neuroendocrine cells (PNECs) are sensory epithelial cells that signal to the brain through sensory neurons and locally through neuropeptides and neurotran...

$7.53M
USD
Completed NON-SBIR/STTR RPGS
Multi-Lineage Modulation of cardiac neural crest cells during cardiac development
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of Pittsburgh At Pittsburgh United States 2024 – 2025

Project Abstract Congenital heart disease (CHD) is the most common birth defect with complex CHD causing significant morbidity/mortality. Therapies targeting adult heart failure ha...

$5.07M
USD
Completed NON-SBIR/STTR RPGS
The Impact of Underlying Behavioral Mechanisms on a Home-Based Pulmonary Rehabilitation Program
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Mayo Clinic Rochester United States 2024 – 2025

PROJECT SUMMARY/ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is one of the top five causes of disability among middle-aged US adults. Exercise-based pulmonary rehabilitati...

$4.77M
USD
Completed NON-SBIR/STTR RPGS
Sex Differences in Gut Metabolite-Immune Interplay in Hypertension and Renal End-Organ Damage
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Augusta University United States 2024 – 2025

PROJECT SUMMARY/ABSTRACT Nearly half of the ~116 million Americans with hypertension are salt-sensitive and confer a 3-fold higher risk of developing cardiovascular disease. Only 2...

$6.39M
USD
Completed NON-SBIR/STTR RPGS
Development of lesion-targeted lncRNA nanotherapeutic for vascular smooth muscle dysfunction
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Arizona State University-Tempe Campus United States 2024 – 2025

PROJECT SUMMARY Neointimal hyperplasia (NIH) is a significant issue that arises from vascular damage during interventions, leading to arterial wall thickening and lumen loss. This...

$4.08M
USD
Completed NON-SBIR/STTR RPGS
Determining the Mechanisms of Radiation Biomodulation of the Ventricular Tachycardia Arrhythmogenic Substate
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE University of Pennsylvania United States 2024 – 2025

Project Summary Cardiovascular disease is the leading cause of death in the United States and accounts for 1 in every 5 deaths. Sudden cardiac death is responsible for nearly half...

$8.12M
USD
Completed NON-SBIR/STTR RPGS
Effectiveness of Therapies for Heart Failure with Mid-Range Ejection Fraction
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Massachusetts General Hospital United States 2024 – 2025

Project Summary / Abstract Evidence from trials has established that 4 separate classes of guideline-directed medical therapies (GDMT) for heart failure with reduced ejection fract...

$7.78M
USD
Completed OTHERS
All of Us Pennsylvania (AOU PA) Research Program
OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEA... University of Pittsburgh At Pittsburgh United States 2024 – 2025

All of Us Pennsylvania (AOU PA) embraces research equity as a fundamental principal and prioritizes engagement and enrollment of diverse participants by bringing the All of Us Rese...

$12.5M
USD
Completed OTHERS
Southeast Enrollment Center Consortium 2 (SEEC-2)
OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEA... University of Miami School of Medicine United States 2024 – 2025

The All Of Us Research Program (AOURP) is a historic effort to enable 21st century biomedical research that will benefit all persons in the USA. The inclusion of at least 1 million...

$12.5M
USD
Completed OTHERS
All of Us Research Program New York Consortium
OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEA... Icahn School of Medicine At Mount Sinai United States 2024 – 2025

The All of Us (AoU) Research Program aims to create one of most diverse health databases in history. To meet this ambitious goal and build upon the program’s progress, we are propo...

$12.5M
USD
Completed OTHERS
All of Us Coast-to-Coast Strong UBR Recruitment, Retention, and Facilitation (C2C SURRF) through Innovation
OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEA... Yale University United States 2024 – 2025

The Coast-to-Coast Consortium (C2C) proposes Strong UBR Recruitment, Retention, and Facilitation through innovation (SURRF). C2C combines experienced and new sites to provide innov...

$12.5M
USD
Active HIV/AIDS
President's Emergency Plan for AIDS Relief - PEPFAR Operational Plan Programs
Department of State U.S. Government - Department of State Angola 2024 – 2026

The DoD HIV/AIDS Prevention Program (DHAPP) mission is to reduce the incidence of HIV/AIDS among partner militaries across the globe by assisting in developing and implementing cul...

$113
USD
Active Development
2023-08-15T00:00:00Z
Unknown Funder Unknown Funder 1 2024 – 2030

2025-12-17T12:02:59Z Planned start date of the activity