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The vasculature as a target for therapy in brain tumors
Glioblastomas are aggressive gliomas with a grim prognosis, characterized extreme invasiveness and abnormal vessels.The abnormal vessels can promote tumor progession by providing a...
Avoidance of disease
Throughout evolution, contagious diseases have been a fatal threat to humans and other species.Research suggests that behavioral avoidance of sick individuals is the first, and pro...
Ett steg längre för patienter med benartärsjukdom
Bakgrund:Benartärsjukdom (BAS) är en vanlig manifestation av ateroskleros och kan leda till kroniska smärtor, sår och amputation. Benartärsjukdom är även starkt kopplad till risk f...
The Loop Generation: Practices, Aesthetics, and Philosophies of Repetition in Contemporary Composition
Repetition is one of music’s most fundamental and cross-cultural features.In most musical discourse, repetition is considered as an event void of information; a mere reiteration of...
Mapping the virus-host transcriptional landscape for a better understanding of dengue disease
Despite more than 100 million infections annually and extensive scientific efforts to understand disease mechanisms, the clinical course of dengue infection, progression to severe...
Prevention and treatment of acute kidney injury (AKI) in patients undergoing cardiac surgery or heart/lung transplantation
Background: Cardiac surgery and heart/lung transplantation are established treatments for various serious heart/lung conditions. Acute kidney injury (AKI) is a common complication...
Model disorders to understand autoimmunity
Autoimmune disease is the third leading cause of morbidity and mortality in the Western hemisphere, surpassed only by heart disease and cancer.Our immune system has evolved to comb...
Fictional prose and language change. The role of colloquialization in the history of Swedish 1830–1930
The project aims to investigate colloquialization in the history of Swedish (c. 1830—c. 1930) by exploring fictional prose. The term colloquialization refers to the incorporation o...
The Biocultural Heritage of Sicilian Olive Trees
The old olive cultural landscapes of Sicily are important historical archives.With climate change and increasing abandonment of the Sicilian countryside, the old olive cultural lan...
Bio-conversion of non-food bio-resources to novel feeds for salmonids - a Nordic approach
The rapid growth in the aquaculture industry puts large demands on feed resources. The aquaculture sector must find alternative strategies to grow sustainably.Cultivating microbes...
Physiology shapes the happy salmon – a systems approach to sustainable feeds for stimulation of growth, welfare and survival in salmon farming
The project aims to provide solutions for a successful Atlantic salmon smolt production using novel sustainable feeds that are applicable in modern RAS-systems.Current smolt produc...
Machine learning applied to predicting and preventing production loss in aquaculture
Up to 20% of farmed salmonids die before reaching slaughter. This occurs during stressful situations such as delousing, deteriorating water quality, and transport.This is a serious...
The role of early visual perception for neurodevelopment in very preterm infants
The purpose of this project is to delineate early risk factors and identify biomarkers for neurodevelopmental impairments (NDI) in very preterm infants, affecting around 20-30% of...
Facilitating detection, understanding production, and improving mitigation of undesired taste and odour compounds in aquaculture
The overall aim of the project FLAVOUR, is to detect, prevent and remove off-flavour and undesired odour in fish farmed in Recirculated Aquaculture Systems (RAS).Off-flavour compou...
Overcoming barriers to nucleic acid therapeutics in cancer
Nucleic acid-based drugs, e.g., siRNA, antisense and mRNA-based drugs, are a novel class of drugs that offer the prospect to revolutionize medical therapy in general and cancer the...
Re-defining care and reasoning in ST-elevation myocardial infarction by shifting focus to myocardial stunning
Purpose:Acute ischemic heart failure (AIHF) is a common life-threatening acute cardiovascular condition. Cardiac dysfunction in AIHF often involve myocardial tissue that is not irr...
Epigenetic landscapes pave the way for drug development and intervention in inflammatory heart failure
Bakgrund:Cardiovascular diseases (CVDs) are the primary cause of morbidity and mortality globally and share an inflammatory pathogenesis. Heart failure (HF), can be associated with...
Education for the new normal: ´Bildung´ in the Anthropocene
The ecological footprint of humanity is a threat to the global environment.Conceptualizing these changes in terms of the Anthropocene is a way to frame the effects that humans have...
Development of new stereoselective reactions
This research proposal deals with the study and development of new, stereoselective reactions using transition metals (iridium) as chiral catalysts.The novelty lies not on the desi...
Development of dynamic network-based models of brain plasticity and vulnerability to traumatic brain injury.
By bringing together concepts and ideas that are rooted in temporal network theory, dynamical systems theory, and time-series analysis, we aim to develop a dynamic network-based ap...