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606,025 grants found
Showing 36,201 – 36,220 of 606,025 grants
Role of FGF21 in DMD
PROJECT SUMMARY Duchenne Muscular Dystrophy (DMD) is the most common muscular dystrophy seen in children, which affects both muscle and bone. To date, the mechanisms that contribut...
Early Predictors of Infant-Parent Coordinated Attention and Word Learning in Preterm and Full-Term Infants
PROJECT SUMMARY Preterm birth (PT,
Personalized Computational Modeling for Predicting Hemodynamics in Borderline Left Ventricles
The decision to perform a biventricular repair (BiVR) or single ventricle palliation (SVP) in patients born with a borderline left ventricle (BLV) remains challenging and subjectiv...
New Von Hippel Lindau (VHL) tumor suppressor signaling in renal cancer
Project Summary Clear cell renal cell carcinoma (ccRCC), which accounts for approximately 85% of all renal cancers, is resistant to a variety of cancer therapies and is highly leth...
Short-course rifapentine for TB prevention for all: clinical pharmacology matters
PROJECT SUMMARY Tuberculosis (TB) is the leading cause of death among people with HIV (PWHIV), and the risk of morbidity and mortality is also high among young children and pregnan...
A secure analytics platform to study the prognosis of people with HIV in the USA, Canada and Europe and comparative effectiveness of treatment regimens: the Antiretroviral Therapy Cohort Collaboration
PROJECT SUMMARY/ABSTACT The HIV epidemic has changed dramatically since the introduction of effective antiretroviral therapy (ART), which substantially increased the life expectanc...
The development of a GMP eDHFR vector to monitor investigational CAR T cell therapies
Abstract The development of cell and gene therapies like Chimeric Antigen Receptor (CAR) T cells has necessitated new technologies that can monitor the biodistribution and traffick...
Policy and implementation context of an unconditional cash transfer program to address homelessness and improve HIV service uptake among marginalized youth in the United States
Rates of homelessness among youth and young adults living in the United States have more than doubled in the last decade, and LGBTQ youth face a higher level of housing insecurity...
Revealing new short tandem repeat variation in the human population across sequencing technologies: towards rare disease diagnosis and discovery
Abstract Short tandem repeats (STRs) are 1–6 bp repetitive and highly polymorphic DNA sequences. Expansions in dozens of STRs are associated with genetic disease. However, STRs are...
Exploration of D-Glucose and D-Mannose Metabolism to Target arenaviruses
PROJECT ABSTRACT/SUMMARY The viruses belonging to the family Arenaviridae contain several causative agents of hemorrhagic fever in humans. For instance, Lassa virus causes Lassa fe...
Host-virus interactions in hantavirus glycoprotein assembly
PROJECT SUMMARY/ABSTRACT Rodent-borne orthohantaviruses (hereafter, hantaviruses) are an important group of zoonotic bunyaviruses associated with over 50,000 annual diagnosed cases...
Deciphering Cellular and Genetic Features that Give Rise to Osteonecrosis of the Jaw
ABSTRACT Osteonecrosis of the jaw (ONJ) is a damaging condition characterized by exposed and necrotic bone in the maxillofacial region, and arises most commonly in patients taking...
Discovery and characterization of protective Influenza Type B Virus neuraminidase antibodies
Project Summary/Abstract Influenza causes an estimated 1 billion cases yearly, with severe cases leading to fatal bronchopneumonia, particularly in vulnerable populations. Influenz...
INL Sarajevo Combatting Corruption thru Data Driven Analysis
INL Sarajevo Combatting Corruption thru Data Driven Analysis
USAID Travel and Transportation
Administrative costs and operating expenses of USAID contributing to Travel and Transportation.
USAID Equipment, Lands, and Structures
Administrative costs and operating expenses of USAID contributing to Equipment, Lands, and Structures.
Information Redacted
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INL 9933 - LOA with IOM on Combating Information Redacted in Geor
INL 9933 - LOA with IOM on Combating Information Redacted in Geor
USAID Advisory and Assistance Services
Administrative costs and operating expenses of USAID contributing to Advisory and Assistance Services.
Aviation Safety Web-Based Training
Waived costs for Aviation Safety Web-based training for 1 participant from Kenya