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606,025 grants found
Showing 26,401 – 26,420 of 606,025 grants
Design and development of generalizable countermeasures against prototype Phenuiviruses
PROJECT SUMMARY/ABSTRACT Prototype pathogens are those that, if well-characterized, can be used to develop generalizable medical countermeasures (MCMs) against new or unknown but r...
Core A: Administration, Communication and Project Management
CORE A: SUMMARY/ABSTRACT This Program Project comprises four individual projects, which will: extend the WISDOM Study to evaluate the use of subtype-specific risk models and associ...
Project 4: CISNET Modeling of outcomes and cost for risk-based screening strategies
Project 4 will evaluate the benefits, harms, and costs of personalized screening using one of the CISNET models of breast cancer. We will evaluate the current approaches to persona...
Core B: Biostatistics and Bioinformatics
CORE B: SUMMARY/ABSTRACT The Biostatistics and Bioinformatics Core’s primary goal is to collaborate with the P01 Investigators and other Core resource scientists to ensure that res...
Core C : Population Genomic Risk Assessment
CORE C: SUMMARY/ABSTRACT A polygenic risk score (PRS) combines risk information from many common genetic variants associated with a disease to predict the risk of that disease. PRS...
Unravelling the role of gene therapy on spinal disc mediated low back pain
PROJECT SUMMARY: Intervertebral disc degeneration (IVDD), the cause of low back pain (LBP), has been connected to a substantial socioeconomic burden, pain, and loss of function for...
Parental psychological control in Mexican immigrant families: A culturally sensitive measure and mechanism
I aim to become an independent researcher who studies parenting in diverse cultures via multiple methods and who builds, tests, and evaluates culturally sensitive preventive interv...
Insights into EHMT1 Variants in the Neurodevelopmental Disorder Kleefstra Syndrome through Structural Dynamics and Functional Analysis
Euchromatic histone methyltransferase 1 (EHMT1, also known as GLP) is a key histone methylation writer intricately associated with Kleefstra Syndrome (KS), a multifaceted neurodeve...
The SHARP Study: Developing Acceptability, Feasibility, and Fidelity of a Reminiscence-based Cognitive Health Intervention Across Three Black American Communities
PROJECT SUMMARY The proposed training plan prepares Dr. Croff to develop expertise in Reminiscence Therapy, measures of cognition and social engagement, and dissemination and imple...
Human Embryonic Stem Cell Models for Studying Mechanisms Underlying Changes In Inhibitory Synapses in Down Syndrome
ABSTRACT: Down syndrome (DS), the chromosomal disorder caused by trisomy of chromosome 21 (Tri21), presents many neurological conditions, including intellectual disability (ID), au...
Quantitative Assessment of Pelvic Floor Muscle Fitness in Myofascial Pelvic Pain
PROJECT SUMMARY Myofascial Pelvic Pain (MPP) is a frequently overlooked musculoskeletal cause of chronic pelvic pain affecting 10-20% of all adult women. Pelvic floor muscle tighte...
Feasibility of a music listening intervention for mental health recovery in chronic stroke
Project Summary This is a feasibility trial testing music listening as an intervention for mental health recovery after stroke. Stroke disproportionally affects older individuals a...
1/2 Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder
PROJECT SUMMARY Premenstrual dysphoric disorder (PMDD) is a severe affective disorder impacting millions of women worldwide, thought to be due to impaired sensitivity to hormone fl...
Development of a smart transformable nanotherapeutic against cancers with acquired resistance to EGFR-targeted therapies caused by MET amplification
Title: Development of a smart transformable nanotherapeutic against cancers with acquired resistance to EGFR-targeted therapies caused by MET amplification Study Section & Awar...
UNM Climate Change and Health for the Alliance and Novelty of Geospatial and Exposure Science (CHANGES) Center
Project Summary We propose the creation of the Climate and Health Allied Network for Geospatial and Environmental Science (CHANGES) Exploratory Research Center at the University of...
Administrative Core
Summary The Administrative Core (AC) of the UNM CHANGES (Climate and Health Allied Network for Geospatial and Environmental Science) Center is tasked with the ambitious objective o...
Environmental Disasters and Impacts on Health Care Systems
Lavin_Gong – Project Summary How climate-related disasters impact health and regional risk is not fully known. Our long- term goal is to improve health sector preparedness, resilie...
Linking Wildfire Smoke to Cancer
Project Summary Climate change is fueling dramatic increases in the frequency, duration, and intensity of wildfires in the Western USA and globally. The contribution of wildfire sm...
Community Engagement Core
Project Summary The Community Engagement Core (CEC) of the University of New Mexico Climate and Health Allied Network for Geospatial and Environmental Science (UNM CHANGES) Explora...
Data Core
PROJECT SUMMARY The Data Core (DC) aims to become a shared resource and research hub that leverages campus-wide resources and expertise across the University of New Mexico (UNM) an...