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Co-creating pathways to desirable nature futures of temperate lakes
Many lakes in Europe reside in a degraded ecological state.This project aims to improve lake management outcomes for long-term provisioning of ecosystem services by more effectivel...
Sustainable nutrient cycling of nitrogenous and phosphate wastes for aquatic ecosystem restoration and nourishment
The SUSTAIN-R proposal aims to introduce innovative approaches (tools, methodologies and devices) for the restoration of aquatic systems with nutrient cycling and reuse of excess a...
BREATHE - Monitoring river metabolism to assess ecosystem services
Current indicators used in national river health assessment systems do not reflect well the structure and function of aquatic ecosystems and are difficult to translate into ecosyst...
HALOBISE: Platform to understand the effects of the harmful algal bloom holobiont in a changing environment to predict their impact on aquatic ecosystem services
Climate change and anthropogenic pressure modify the aquatic dynamics and interacting factors that affect aquatic ecosystem function and services.Harmful algal bloom (HAB) is one o...
A double tap: ribosomal protection though rRNA methylation and antibiotic displacement
Protein synthesis by the ribosome is central to all life. The ribosome is therefore a major antibiotic target, and bacteria employ numerous mechanisms to protect it.One of the most...
Discovering the interplay between antibiotic and phage resistance in bacteria
The antibiotic resistance crisis has led to renewed interest in the use of phage therapy for treating bacterial infections that are unresponsive to antibiotics. Compassionate use c...
Supporting the value of antibiotics through network changes and policies
Antibiotics are a fundamental resource for human health.However, their value is progressively being destroyed due to several problems including lack of antibiotic innovation, misus...
Optimised treatment of antibiotics in critically ill patients
Inappropriate use of antimicrobials is the major driver of antimicrobial resistance.This includes unnecessary use such as treating with antibiotics when there is no infection as we...
Who’s got the plasmid? Tracking the spread of antimicrobial resistance genes in the human gut microbiome at the single-cell level
Purpose and aims: Bulk shotgun metagenomic sequencing (bulk metaG) methods, which sequence all DNA present in a sample, are being used globally for antimicrobial resistance (AMR) s...
Commensal Friends or Foes? Bacterial Injection Systems in Skin Microbiomes and Commensals As Novel Avenue for Combatting Infections and Antimicrobial Resistance
The skin microbiome plays a crucial role in maintaining skin homeostasis, protection against pathogens, and modulating immune response.It also is a hot spot for antimicrobial resis...
Mechanisms and clinical effects of antibiotic interactions
Antibiotic therapy increasingly relies on the use of combinations of antibiotics, especially for serious and difficult-to-treat cases.Even though combinations have been used for ov...
Mechanism and implications of ABC-F-mediated antibiotic resistance in clinically relevant bacteria
We will extend our live-cell single-molecule tracking techniques to study how ABC-F proteins mediate antibiotic resistance in clinically relevant bacteria.In particular, we will st...
Antibiotic Efficacy and Enterobacterial Resistance Spread in Infected Human Tissue Resolved by Organoid Modelling
Antibiotics are crucial for modern medicine, but resistance spread threatens their use and urges the need for intensified research.Studies of bacterium - antibiotic interactions an...
Pathogenesis and new therapeutic targets in drug-resistant tuberculosis (TB): Path-to-Resist-TB
Multidrug-resistant tuberculosis (MDR-TB) is a serious global health problem resulting from inappropriate antibiotic treatment of pulmonary TB, which highlights the need for new dr...
Mechanisms behind antibiotic recalcitrance
This project aims to understand antibiotic recalcitrance, a bacterial survival mechanism including both persistence and tolerance and, which contributes to emergence of antibiotic...
Lab to Market: Natural Oat ß-glucan elevating flavour and health in Plant protein- pioneering clean-label foods
The inherent beany taste and bitterness of legumes, faba beans and yellow peas, pose problems in plant-based diets. They can be masked by costly e-coded additives, but there is gro...
Food and drinks for seniors
The project aims to develop high-energy, high-protein nutritious food for seniors and thickened beverages for those with swallowing disorders (dysphagia).The goal is to address pre...
BamPinePanels: Production of Eco-Friendly Panels from Welded Bamboo or Pine
The project addresses four challenges within the forestry industry: increased interest in timber construction, low processing of harvested timber, negative environmental impact of...
NIHR ICA Pre-doctoral Clinical and Practitioner Academic Fellowship 2024
Training Award
NIHR ICA Pre-doctoral Clinical and Practitioner Academic Fellowship 2024
Training Award