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199,248 grants found
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Turbulence fluxes across the air-sea-ice interface in the marginal ice zone and their influence on polar cyclones
Sea ice floes, which vary in size from centimeters to hundreds of kilometers, have a significant impact on momentum and heat fluxes across the air-sea-ice interface within the Marg...
Reactive fractionation of biomass to give lignin carbonates
To realize a biorefinery, all components of biomass should be valorized: including lignin. In current biorefineries such as pulp mills the lignin fraction is compromised in favor o...
Diagnosing neglected tropical diseases with REASSURED and sustainable point-of-care-tests
Neglected Tropical Diseases (NTDs) affect >1 billion people and cause 200,000 deaths, mostly in impoverished communities in low-income countries such as Congo and Ethiopia a...
How sensory input is integrated to steer straight
All animal navigators are faced with the challenging task of making sense of multiple directional cues to steer their desired course.But due to variable terrain, unpredictable weat...
Ultrafast dynamics of correlated electrons in strong laser fields: investigations of effective many-body spaces
The photoelectric effect was explained by Einstein more than 100-years ago. His invention of “light particles” (photons) now marks the birth of quantum mechanics. Today, advanced l...
Determinants of transcription factor specificity in flowering time and flower development in Arabidopsis thaliana
The induction of flowering is critical for the reproductive success of plants and is therefore controlled by an intricate regulatory network comprised of numerous transcription fac...
Beamforming Integrated Sub-THz Compact circUITS - BISCUITS
The exponential growth in data rates and capacity of wireless systems needs more bandwidth, which can be found at higher frequencies. In 5G systems the mm-wave range was therefore...
Heavy ions in Earth’s magnetotail: Redistribution and total transport
To understand atmospheric escape at Earth, we must first understand the plasma transport in the magnetotail. The transport of H+ ions is quite well understood, but not that of heav...
Excited state catalysis in chemical synthesis
The modern world relies on chemical synthesis in order to build the pharmaceuticals, agrochemicals and materials that form the basis of modern life.The overall objective of this re...
Molecular-scale understanding of current and future food proteins behaviour during falling-film evaporation
Proteins are vital to the diet.To reduce the climate impact of foods, which generates one-third of human-caused greenhouse emissions, the transition from meat-based to alternative...
A novel paradigm in islet regulation: microRNA control of α- and β-cells during development of type 2 diabetes
Type 2 diabetes (T2D) is a global health issue, impacting countless lives worldwide.The role of microRNAs (miRNAs) in the regulation of insulin and glucagon secretion represents a...
Development of cutting-edge combination therapy using neurotrophin, anti-amyloid and galantamine therapy for Alzheimer´s disease
Alzheimmer´s disease (AD) is a complex and deadly disease.Recent clinical trials reported beneficial effects of anti-amyloid immunotherapies on cognitive decline, but the cognitiv...
A blood brain barrier permeable molecular chaperone – mechanisms against neurodegeneration and potential as transport vehicle into the CNS
Amyloid is associated with Alzheimer´s disease (AD) in which Aβ42 and tau form fibrils, and with Parkinson´s disease (PD) where α-synuclein (α-syn) aggregates into fibrils.Targetin...
Deciphering Tumor Microenvironment and Macrophage Polarization in Colorectal Peritoneal Metastasis
Colorectal cancer-associated peritoneal metastasis (PM) is a serious health concern marked by high mortality rates and recurrence despite treatment advancements.Macrophages in the...
Deciphering the splicing blueprint of human myeloid cells in non-alcoholic steatohepatitis
Non-Alcoholic Steatohepatitis (NASH) is on the verge of becoming the leading cause of liver-related morbidity and mortality in the foreseeable future.The FDA´s approval of the inau...
Registry-based research for identifying and addressing the barriers to the implementation of care in patients with heart failure
Purpose and aims. Heart failure (HF) is common and linked with poor outcome. Guideline-directed medical therapy (GDMT) improves outcome but is poorly implemented.Barriers to implem...
Leveraging Alzheimer’s disease subtypes toward novel biological insight and precision medicine
Alzheimer’s disease (AD) is characterized by the build up of pathological proteins amyloid-ꞵ and tau. These proteins can be imaged in the living human brain using positron emission...
Monoclonal antibodies and intestinal organoids for human norovirus prevention studies
The purpose of the project is to identify effective tools for prevention of human norovirus infections.To fulfill the purpose I will focus on two aims: isolation and characterizati...
Microplastic- and Nanoplastic Particles as Carrier of Urban Stormwater Pollutants and their Removal Mechanisms in Alternative Sorption Materials
The aim of this research project is to determine the processes involved in the transport of metals and organic pollutants on the surfaces of micro- and nanoplastic particles (MNPs)...
Polaritonic Chemistry: Vibrational strong coupling in solution
Light is widely used in chemistry today as a classic probe and tool for initiating processes.By confining light to small volumes, the quantized light field can influence molecular...