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Showing 33,72133,740 of 606,025 grants

Active OTHER RESEARCH-RELATED
Deprescribing for Post-Acute Care Older Patients with Dementia in Home Health Care
NATIONAL INSTITUTE ON AGING University of Rochester United States 2024 – 2029

PROJECT SUMMARY/ABSTRACT Older persons with Alzheimer’s disease and related dementias (ADRD) often use potentially inappropriate medications (PIMs) - medications with a risk of har...

$2.43M
USD
Active OTHER RESEARCH-RELATED
Advancing CBPR to Spearhead Health Equity for Minority Older Adults.
NATIONAL INSTITUTE ON AGING University of Alabama At Birmingham United States 2024 – 2029

PROJECT SUMMARY Systemic racism, lack of access to healthcare, implicit bias in care provided, and other injustices have contributed to reprehensible healthcare disparities in mino...

$1.61M
USD
Completed OTHER RESEARCH-RELATED
Assessing for and Intervening upon Early Childhood Violence Exposure in Pediatric Primary Care Settings
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... University of Washington United States 2024 – 2026

PROJECT ABSTRACT Childhood exposure to violence (CEV) is a significant and preventable public health problem in the United States. Children of all ages are at risk for CEV, but chi...

$1.15M
USD
Active NON-SBIR/STTR RPGS
Allogeneic virus-specific T-cell therapy after hematopoietic stem cell transplant: determinants of treatment success and failure
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Cincinnati Childrens Hosp Med Ctr United States 2024 – 2029

ABSTRACT: Infections caused by double stranded DNA viruses are a common complication after allogeneic hematopoietic stem cell transplantation (HSCT), occurring in 82% of patients u...

$6.76M
USD
Active NON-SBIR/STTR RPGS
Artificial Intelligence-Based Methods to Characterize Kidney Macrostructure from Pre- and Post-Nephrectomy Computed Tomography Images
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Mayo Clinic Rochester United States 2024 – 2028

PROJECT SUMMARY/ABSTRACT The prevalence and burden of chronic kidney disease (CKD) is increasing worldwide. Patients who undergo radical or partial nephrectomy for kidney cancer re...

$3.51M
USD
Completed NON-SBIR/STTR RPGS
Development of a novel syphilis molecular diagnostic assay for a point-of-care multiplexed genital ulcer panel test on giant magnetoresistive biosensors
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... Magic Lifescience, Inc United States 2024 – 2026

PROJECT SUMMARY There is a large unmet need for fast and effective point-of-care (POC) molecular diagnostic (MDx) testing for congenital and adult acquired syphilis. Current syphil...

$1.64M
USD
Completed RESEARCH CENTERS
Epidemiologic burden of Sickle Cell Disease: Evaluating Healthcare Utilization of Persons with Sickle Cell Disease in Delaware
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES Nemours Children'S Hospital, Delaware United States 2024 – 2026

We aim to undertake an epidemiologic assessment of the SCD population in Delaware using statewide surveillance data.We will partner with the Delaware Sickle Cell Disease Collection...

Active NON-SBIR/STTR RPGS
Machine learning in publicly available geotagged data to allow monitoring of maternal and child health
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Stanford University United States 2024 – 2029

Over 95 percent of maternal and child deaths globally occur in low- and middle-income countries (LMICs) where reliable death registries are mostly unavailable and other dependable...

$6.43M
USD
Active RESEARCH CENTERS
Center for Latino Health Research Opportunities-CLaRO
NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH D... University of Miami Coral Gables United States 2024 – 2029

Project Summary/Abstract Latino populations in Miami-Dade County (FL) continue to experience health disparities and health inequities. To address these critical public health issue...

$6.83M
USD
Completed NON-SBIR/STTR RPGS
Early onset colorectal cancer: from symptoms to treatment in a large, safety-net cohort
NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH D... Ut Southwestern Medical Center United States 2024 – 2026

PROJECT SUMMARY (ABSTRACT) Early-onset colorectal cancer (EOCRC; CRC diagnosed at < 50-years of age) is a known and worsening public health problem, with alarming increases in i...

$2.05M
USD
Completed NON-SBIR/STTR RPGS
Peptides for the treatment of pulmonary fibrosis
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE Medical University of South Carolina United States 2024 – 2026

ABSTRACT Fibroproliferative illnesses leading to organ fibrosis and failure are responsible for approximately 45% of deaths in developed countries. Whether idiopathic, triggered by...

$4.64M
USD
Active TRAINING, INDIVIDUAL
Helping clinicians address digital information about contraception with adolescents
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... University of North Carolina Chapel Hill United States 2024 – 2029

Abstract: Adolescents need accurate information about contraception to participate in shared decision-making about sexual and reproductive health, including preventing teen pregnan...

$412.4K
USD
Completed OTHER RESEARCH-RELATED
Neurogenic Bladder Research Group (NBRG) symposium: Partnering with Engineering in Neurogenic Bladder Research
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Methodist Hospital Research Institute United States 2024 – 2025

Abstract Neurogenic lower urinary tract dysfunction (NLUTD), formerly “neurogenic bladder,” encompasses bladder and sphincter abnormalities resulting from neuromuscular diseases or...

$100K
USD
Active OTHER RESEARCH-RELATED
Reducing Disparities in Mental and Metabolic Health among Predominantly Low-Income, Black and Hispanic Women with and without HIV
NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH D... New York University United States 2024 – 2029

ABSTRACT In the United States, Black and Hispanic women (BHW) have the greatest risks of poverty, type 2 diabetes (T2D), and depression, the scope and intersection of which epitomi...

$1.68M
USD
Completed SBIR-STTR RPGS
Neural Ice Technology for Treatment of Pain
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETA... Brixton Biosciences, Inc United States 2024 – 2026

Project Summary Total knee arthroplasty (TKA) is one of the most performed orthopedic surgeries to relieve joint pain in patients with end-stage osteoarthritis (OA) or rheumatic ar...

$9.99M
USD
Completed NON-SBIR/STTR RPGS
Engineering simian-compatible HIV-1
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEA... University of North Texas Hlth Sci Ctr United States 2024 – 2026

PROJECT SUMMARY/ABSTRACT Construction of infectious and pathogenic HIV-1, or HSIV -- an essentially HIV-1 backbone having minimal SIV gene fragments -- for the simian model will br...

$1.84M
USD
Active RESEARCH CENTERS
Center for Latino Health Research Opportunities-CLaRO - Administrative Core
NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH D... University of Miami Coral Gables United States 2024 – 2029

Project Summary/Abstract The Administrative Core of the proposed Center for Latino Health Research Opportunities (CLaRO) will oversee and direct the infrastructure and collaborativ...

Completed TRAINING, INDIVIDUAL
Pathways linking childhood and intergenerational trauma at the US-Mexico border with cardiovascular health.
NATIONAL INSTITUTE ON MINORITY HEALTH AND HEALTH D... University of Arizona United States 2024 – 2026

Project Summary/Abstract: Adverse childhood experiences (ACEs) are strongly associated with cardiometabolic and mental health outcomes in adulthood. Mechanisms of this relationship...

$489.7K
USD
Completed SBIR-STTR RPGS
Development and Commercialization of a weight monitoring platform for wheelchair users
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD... Nurelm E-Business Software United States 2024 – 2026

Project Summary/Abstract This project will complete the final design and development steps to commercialize the Fast In-Bed Tracking (FIT) Platform, which is an e-Health and wellne...

$9.87M
USD
Active NON-SBIR/STTR RPGS
Glycosaminoglycan Targeting Treatment for Prostatic Hyperplasia and Fibrosis
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND K... Augusta University United States 2024 – 2028

Benign prostatic hyperplasia (BPH) is an age-related progressive pathologic condition in aging men. More than 50% of patients with BPH have lower urinary tract symptoms (LUTS), a c...

$6.29M
USD