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Role of extracellular matrix as regulator of ageing through mechanosignaling
A recent work published by the host laboratory had redefined aging as a mechano-disease. Transcriptional co-factors YAP/TAZ, masters of mechanotransduction, were critical in stroma...
METabolic interplay petween peroxisome-endoplasmic reticulum contACT sites and mitochondria-endoplasmic reticulum contact sites during metabolic dysfunction-associated fatty liver disease
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the liver manifestation of metabolic syndrome, consisting in a hepatic accumulation of lipids.While MAFLD is predict...
Boride-derived Highly Efficient Material for Green Hydrogen Generation and Zn–air Battery
The world energy demand is expected to grow by more than 25% by 2040, according to the world energy outlook by the International Energy Agency.To tackle this significant and urgent...
JAM-A and HER2/3 Antagonistic Strategy In Targeting breast cancer
Breast cancer is the most common female malignancy, and a leading cause of death.Although molecular technologies have led to new therapeutic targets for breast cancer, much remains...
Heterologous expression of natural products from microbes living in a self-sustaining environment
The increases in antimicrobial resistance and infections caused by microbes, such as mucormycosis (black fungus disease) on Covid-19 patients, highlight the urgent need for new ant...
Democratic elite perceptions of Economic and Monetary Union
D-EMU provides highly innovative research on a crucial challenge for democracy in the EU: the legitimacy of governance in the Economic and Monetary Union (EMU).It focuses on confli...
Fascist Literature: Three Poetry Competitions in Fascist Italy
FascLit investigates the relationship between literature and totalitarianism by focusing on three literary prizes which took place in the 1930s in Fascist Italy: “Poeti del tempo d...
NUTRIENT FLUCTUATIONS AND THE INTEGRATIVE STRESS RESPONSE AS METABOLIC CELL FATE DETERMINANTS IN B CELL LYMPHOMA
Metabolic reprogramming enables cells to adopt different phenotypes, providing flexibility in response to environmental stress, of particular relevance during tumour development.I...
CRYOsphere-Ocean: Effect on the MIcrobial Communities in the Southern Ocean
The melting of the cryosphere is among the most conspicuous consequences of climate change, and a significant source of freshwater to the Southern Ocean (SO).As a crucial sink for...
Element-selective impulsive electronic and vibrational spectroscopy of iron-sulfur clusters
The catalytic activity of metalloproteins and cofactors is at the heart of biological systems’ functioning.Biological reactions occur under physiological conditions in stunning con...
Design and Development of 3D Printed Force Transducers
Additive manufacturing (AM), as an advanced manufacturing technique, has the potential to transform the landscape of product development, manufacturing, and logistics, as well as i...
Targeting R2TP/TTT/WAC/mTOR complex in ovarian cancer.
Ovarian Cancer (OC) is the most lethal gynecological tumor and has an especially high impact in Europe. 70% of patients develop an advanced stage due to the lack of early diagnosis...
A Micromotor-driven Triboelectric Nanogenerator with different Propulsion mechanisms
The triboelectric effect is always considered a negative phenomenon in daily life, and this perception was altered when the first triboelectric nanogenerator (TENG) was proposed in...
IMproved Plasminogen Activator based on Cerium oxide nanoparticles for Thrombolysis in ischemic Stroke
Ischemic stroke is the second cause of death worldwide. Recombinant tissue plasminogen activator (rtPA) is the only approved therapeutic agent. However, stroke patients often suffe...
A Unified Description of Flat Space Holography
One of the most challenging open questions in theoretical physics consists in describing quantum mechanics and gravity in a unified framework.Important progress has been made towar...
Privileged Mobility and Transnational Conjugality in Islamic countries: reconsidering global power relations from a gender perspective in Southeast Asia and West Africa
While attention on privileged mobility has predominantly centered on retirees, tourists, lifestyle migrants or obligatory short-term expatriates, scant consideration has been given...
Aviation Zero Emissions 2050
Decarbonisation of Aviation will require strict regulation and monitoring to be aligned with the EU Green Deal in making the EU the world’s first climate neutral region by 2050.EU...
Breaking frontiers of Eddy Current Testing simulations through Discrete De Rham methods
Eddy Current Testing (ECT) is an industrial procedure used to assess the reliability of the most critical facilities of nuclear power plants. Prior to practical usage, ECT requires...
HERMES: Holistic dEcision suppoRt system for infrastructure ManagErS
The HERMES aims at developing a “Holistic dEcision suppoRt system for infrastructure ManagErS”.HERMES faces in an original and integrated way some of the major and most urgent chal...
Overcoming hurdles to the diffusion of environmentally sustainable behaviour
The need for action on tackling climate change has reached a make-or-break moment: we can only deliver on the commitments made in the Paris Agreement if we act now.Given the import...