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20,252 grants found
Showing 19,021 – 19,040 of 20,252 grants
Large scale clinical and economic impact analysis of potentially malignant incidental findings in radiology reports
Abstract Unexpected findings, or incidentalomas, are increasing dramatically with the growth in the use of imaging technology within healthcare organizations. Incidentalomas may in...
MULTIPLEXED ISOFORM QUANTIFICATION IN HER2-POSITIVE BREAST CANCER
While targeted therapy increases overall survival rates in HER2-positive breast cancer patients, most patients will experience recurrence due to resistance to initially successful...
Dihydroceramide desaturase (DES1) as a mediator of receptor tyrosine kinase-driven metastasis in breast cancer
ABSTRACT Despite improvements in treatment, clinical outcomes for late stage breast cancer (BC) remain poor and there is a critical need for new therapies for metastatic disease. H...
A community-based trial of a voluntary smoke-free home intervention in permanent supportive housing for formerly homeless adults
PROJECT SUMMARY The focus of this proposal is on expanding access to voluntary smoke-free homes to formerly homeless residents residing in permanent supportive housing, and examini...
MULTIPLEXED ISOFORM QUANTIFICATION IN HER2-POSITIVE BREAST CANCER
While targeted therapy increases overall survival rates in HER2-positive breast cancer patients, most patients will experience recurrence due to resistance to initially successful...
A community-based trial of a voluntary smoke-free home intervention in permanent supportive housing for formerly homeless adults
PROJECT SUMMARY The focus of this proposal is on expanding access to voluntary smoke-free homes to formerly homeless residents residing in permanent supportive housing, and examini...
Development of A HTLV-1 Vaccine
PROJECT SUMMARY For this proposal we intend to develop a novel vaccine to prevent and possibly treat Human T cell leukemia virus type-1 (HTLV-1) associated diseases. HTLV-1 is a hu...
SEER CORE INFRASTRUCTURE SUPPORT
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
SEER CORE INFRASTRUCTURE SUPPORT
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
Single cell quantification of genomic instability in cancer as a determinant of therapeutic response
PROJECT ABSTRACT Tumor genetic heterogeneity is an extensive feature of cancer biology and underlies patient response to therapy. One aspect of tumor heterogeneity that has been di...
MULTIPLEXED ISOFORM QUANTIFICATION IN HER2-POSITIVE BREAST CANCER
While targeted therapy increases overall survival rates in HER2-positive breast cancer patients, most patients will experience recurrence due to resistance to initially successful...
Multimodal iterative sequencing of cancer genomes and single tumor cells
ABSTRACT Genome sequencing technology has been transformative in the analysis of cancer. From genomic, transcriptomic, and epigenetic data, researchers are making new...
Dihydroceramide desaturase (DES1) as a mediator of receptor tyrosine kinase-driven metastasis in breast cancer
ABSTRACT Despite improvements in treatment, clinical outcomes for late stage breast cancer (BC) remain poor and there is a critical need for new therapies for metastatic disease. H...
Development of A HTLV-1 Vaccine
PROJECT SUMMARY For this proposal we intend to develop a novel vaccine to prevent and possibly treat Human T cell leukemia virus type-1 (HTLV-1) associated diseases. HTLV-1 is a hu...
MULTIPLEXED ISOFORM QUANTIFICATION IN HER2-POSITIVE BREAST CANCER
While targeted therapy increases overall survival rates in HER2-positive breast cancer patients, most patients will experience recurrence due to resistance to initially successful...
Explore the signaling mechanisms of acquired resistance to tyrosine kinase inhibitors in AML
Explore the signaling mechanisms of acquired resistance to tyrosine kinase inhibitors in AML Abstract Acute myeloid leukemia (AML) is a malignant hematopoietic disease and the most...
Large scale clinical and economic impact analysis of potentially malignant incidental findings in radiology reports
Abstract Unexpected findings, or incidentalomas, are increasing dramatically with the growth in the use of imaging technology within healthcare organizations. Incidentalomas may in...
A community-based trial of a voluntary smoke-free home intervention in permanent supportive housing for formerly homeless adults
PROJECT SUMMARY The focus of this proposal is on expanding access to voluntary smoke-free homes to formerly homeless residents residing in permanent supportive housing, and examini...
SEER CORE INFRASTRUCTURE SUPPORT
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...
SEER CORE INFRASTRUCTURE SUPPORT
The purpose of the National Cancer Institute (NCI) Surveillance Epidemiology and End Results (SEER) Program is to assemble and report annual estimates of cancer statistics that per...