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Showing 9811,000 of 44,293 grants

Active RESEARCH GBP
RAPID driven Treatment of Pleural Infection (feasibility study)RAPTOR-f
National Institute for Health and Care Research Oxford University Hospitals Nhs Foundati... United Kingdom 2024 – 2026

Research question: Is it feasible to deliver a definitive randomised trial comparing usual care to RAPID driven care in patients with pleural infection? Background: Pleural inf...

£2.56M
GBP
Active RESEARCH GBP
Development and clinical evidence generation for a rapid, cost-effective, point of care antibiotic susceptibility test for urinary tract infections
National Institute for Health and Care Research Microplate Dx Limited United Kingdom 2024 – 2026

Research Question Antimicrobial resistance (AMR) occurs when bacteria, viruses, fungi and parasites evolve and no longer respond to medicines. There were 4.95 million AMR-associat...

£14.65M
GBP
Active RESEARCH GBP
Understanding the Missing Links: Integrated Health and Social Care for People Experiencing Homelessness
National Institute for Health and Care Research The University of Manchester United Kingdom 2024 – 2026

Homelessness (including street homelessness, temporary accommodation and sofa surfing) is a persistent and growing problem. Homelessness is associated with much greater morbidity a...

£80.67M
GBP
Active RESEARCH GBP
Regulating physician dual practice to advance Universal Health Coverage in low- and middle-income countries. A study to assess existing policies and identify effective regulatory options in Mozambique and South Africa
National Institute for Health and Care Research Queen Mary University of London United Kingdom 2024 – 2027

Background. Doctors in low- and middle-income countries (LMICs) often work simultaneously in public and private clinical services, a phenomenon known as ‘dual practice’. Although s...

£91.42M
GBP
Active RESEARCH GBP
Development of a patient-reported outcome to assess concerns about falling in hospital settings
National Institute for Health and Care Research Imperial College Healthcare Nhs Trust United Kingdom 2024 – 2026

BACKGROUND Concerns-about-falling (previously known as fear-of-falling) are common in older adults with poor physical health – a demographic largely represented by those in...

£1.51M
GBP
Active RESEARCH GBP
Taking TransiCap to market (MAGIC3)
National Institute for Health and Care Research Nottingham University Hospitals Nhs Trus... United Kingdom 2024 – 2027

Background Functional constipation affects 10% of children and young people, and 8% of adults. Management of these patients is challenging and based primarily on symptom reports....

£14.89M
GBP
Completed TRAINING GBP
NIHR ICA Pre-doctoral Clinical and Practitioner Academic Fellowship 2024
Non-NIHR funding Cornwall Partnership Nhs Foundation Trus... United Kingdom 2024 – 2025

Training Award

£721.5K
GBP
Completed TRAINING GBP
NIHR ICA Pre-doctoral Clinical and Practitioner Academic Fellowship 2024
Non-NIHR funding Homerton Healthcare Nhs Foundation Trust United Kingdom 2024 – 2025

Training Award

£299.7K
GBP
Completed TRAINING GBP
Pre-App R3 2024
National Institute for Health and Care Research University of Central Lancashire United Kingdom 2024 – 2025

Training Award

£390.2K
GBP
Active TRAINING GBP
Investigating current practice of prescribing ‘rescue packs’ in COPD in primary care in England
Non-NIHR funding University of Oxford United Kingdom 2024 – 2027

Background Chronic obstructive pulmonary disease (COPD) refers to a group of conditions which cause breathing difficulties, affecting estimated 3 million people in the UK. Without...

£5.24M
GBP
Active RESEARCH GBP
Trauma-informed Care in Children’s Homes: A Realist Co-production Development Study
National Institute for Health and Care Research Pennine Care Nhs Foundation Trust United Kingdom 2024 – 2026

Research question How, when and why can a theoretically-informed evidence-based trauma-informed care intervention tailored for children and young people in care improve care quali...

£3.57M
GBP
Completed RESEARCH GBP
Body Aspect's 3D technology for decidingeligibility of elective breast reduction cases
National Institute for Health and Care Research Body Aspect Ltd United Kingdom 2024 – 2025

Body Aspect's 3D technology for decidingeligibility of elective breast reduction cases

£1.19M
GBP
Completed RESEARCH GBP
Clinical translation of IBEX Bone Health opportunistic osteoporosis screening: A feasibility study
National Institute for Health and Care Research Ibex Innovations Ltd United Kingdom 2024 – 2025

Clinical translation of IBEX Bone Health opportunistic osteoporosis screening: A feasibility study

£1.34M
GBP
Active TRAINING GBP
NIHR ICA Pre-doctoral Clinical and Practitioner Academic Fellowship 2024
Non-NIHR funding Woodstock Road Chemist United Kingdom 2024 – 2027

Training Award

£649.5K
GBP
Active BIOIMAGING TECHNOLOGY DEVELOPMENT AWARD GBP
Molecular annotation of the Drosophila connectome by optimised expansion microscopy
Wellcome Trust Janelia Research Campus United Kingdom 2024 – 2026

Our recent collaborative work has delivered whole brain and nerve cord connectomes (synaptic resolution wiring diagrams) for adult Drosophila – the first for an animal that can wal...

£1.85M
GBP
Active EARLY-CAREER AWARD GBP
Does neuronal activity modulate action potential conduction along myelinated axons in developing neural circuits?
Wellcome Trust University of Edinburgh United Kingdom 2024 – 2029

A new form of brain plasticity, activity-driven modification of axons, has recently been proposed. This is based on many studies indicating brain activity can influence myelinated...

£6.67M
GBP
Active CAREER DEVELOPMENT AWARD GBP
Characterising the clinical heterogeneity and aetiology of Avoidant Restrictive Food Intake Disorder
Wellcome Trust Cardiff University United Kingdom 2024 – 2032

Avoidant Restrictive Food Intake Disorder (ARFID), introduced to the DSM-5 diagnostic classification system in 2013, is a severe feeding and eating disorder marked by food avoidanc...

£22.75M
GBP
Completed DISCRETIONARY AWARD GBP
The Climate Health Summit: Translating Evidence into Action
Wellcome Trust The Physiological Society United Kingdom 2024 – 2025

The Physiological Society (TPS) is seeking support from Wellcome to run a two day conference on the topic of climate change and health at the QEII in London 16-17 July 2025. The co...

£1.7M
GBP
Active MENTAL HEALTH AWARD: UNDERSTANDING ANXIETY AND TRAUMA GBP
Social, Psychological, And Biological Mechanisms Underlying The Impact Of Early Life Adversity On Anxiety-related Disorders: Causal Analysis Of Cohorts From The UK And Brazil
Wellcome Trust University of Bristol United Kingdom 2024 – 2029

Adverse childhood experiences (ACEs, e.g. family violence, parental mental health problems, bullying) carry an elevated risk of anxiety-related disorders, yet underlying mechanisms...

£17.08M
GBP
Active CAREER DEVELOPMENT AWARD GBP
Deciphering neuronal RBP regulation of mRNA transport and translation in synaptic plasticity
Wellcome Trust University of Edinburgh United Kingdom 2024 – 2032

At brain synapses, the direct functional connection between neurons, RNA localization and local regulation of protein synthesis are critical components for sculpting the synaptic p...

£268.29M
GBP