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44,293 grants found
Showing 43,521 – 43,540 of 44,293 grants
Rural youth identities in India: Exploring intersections of nation, gender and technology in areas of civil unrest
I aim to build on my PhD research and policy work on education, identities and rights of marginalised groups (Wadhwa et al., 2010; NCPCR, 2011, 2012b, 2013; Wadhwa, 2019). I aim to...
Reducing the impacts of plastic waste in the Eastern Pacific Ocean
The presence of plastic leaking into the environment is a system failure of monumental proportion that threatens the marine ecosystem and causes physical and chemical contamination...
Determining the role of Wnt signalling & IGFBP6 in enhanced atherosclerosis risk in periodontal patients: biomarker & therapeutic potential evaluation
Heart attacks are one of the leading causes of death in the UK and across the world. The most common cause of heart attacks is the blockage of the arteries that supply the heart. T...
Least Squares PGD Mimetic Spectral Element Methods for Systems of First-Order PDEs
Many mathematical models that describe problems in science and engineering are defined in high dimensional spaces. Examples can be found in a diverse range of application areas suc...
All-Optical Plasma Channels and Electron Injection with Spatio-temporal Control
Particle accelerators are used in many areas of the physical and biological sciences. For example, fundamental studies of the building blocks of matter are carried out with huge ac...
Financial lives and wellbeing in low-income groups post Covid-19 (FinWell-Covid)
Amongst those hit hardest by COVID-19, and the associated social and economic measures put in place to combat it, will be people in low-income settings, and, within that group, tho...
Oh I do like to grow beside the seaside: understanding how and why plants produce DMSP
Billions of tonnes of the organosulfur compound dimethylsulfoniopropionate (DMSP) are made each year by marine algae, corals and bacteria, but some plants also make this important...
Pulse-Downy Mildew Pathosystem: deploying disease resistance, pathogenomics and microbial biocontrol
Pulses, in particular peas and broad beans, are important crops both in the UK and worldwide and they are grown as extensive monocultures. Even with long rotations, the crops are v...
Architectures and Distribution Arithmetic for Coupling Classical Computers to Noisy Intermediate-Scale Quantum Computers
All physical measurements have measurement uncertainty and are best represented with probability distributions. Measurements from sensors feeding machine learning algorithms and me...
Routes of infection, routes to safety: Creative mapping of human-viral behaviours on the bus to understand infection prevention practices
There is an absence of qualitative, interdisciplinary research on the personal application of infection prevention (IP) measures, like hand-washing and mask-wearing, and its effect...
Human genome synthesis
The ability to make any human genome would transform hypothesis driven investigations in diverse areas of biology, genetic-archaeology and biotechnologies. However, there are curre...
Single Cell Expression Atlas
Single Cell Expression Atlas (https://www.ebi.ac.uk/gxa/sc) is an open science resource that offers powerful searches for a gene expression data in different cell types, across tis...
State of the art direct electron detection at the Astbury Biostructure Laboratory
The Astbury Biostructure Laboratory, was established in 2015 with University of Leeds investment, and a Wellcome multi-user equipment award, allowing us to install two Titan Krios...
Live cell imaging capability for research on pathogenic viruses
We request a 75% contribution to purchase two IncuCyte S3 Live-Cell Analysis Systems, together with archive data storage capacity (£189,485).These instruments are designed to acqui...
A genomics approach to unravelling the link between steroid hormone dysregulation and cardio-metabolic disease
Steroid hormone dysregulation has been linked to nearly all leading causes of death, notably cardio-metabolic diseases.Despite this, the aetiological contribution of steroid hormon...
Mapping sensory-motor cerebellar circuits for adaptive behaviour
The cerebellar cortex is thought to form predictive associations between sensory inputs and motor commands: animals leverage these associations to coordinate and adapt movements to...
Mechanisms of Transcriptional Regulation by H3K4 Methyltransferases at CpG Islands
The genetic information of each cell is stored in the nucleus as DNA wrapped around histone proteins, a structure termed chromatin.Apart from packaging DNA into the confined space...
Investigation of the structural and biochemical properties of mammalian tolloid proteinases
The family of BMP1/Tolloid-like proteases (B/TPs) is involved in a variety of important functions in mammalian tissue development. Firstly, B/TPs cut collagen precursors to allow t...
Modelling the impact of increased extracellular matrix stiffness on mammary epithelial cells
Mammographic density (MD) refers to the proportion of the breast occupied by radiographically dense tissue, as assessed by mammography.It has been shown that women with significant...
Pim kinase and the regulation of platelet function, thrombosis and haemostasis
Platelet driven thrombosis continues to account for high levels of mortality worldwide.Despite the therapeutic benefits of current anti-platelet drugs such as aspirin and clopidogr...