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44,293 grants found
Showing 341 – 360 of 44,293 grants
Advanced Machinery & Productivity Initiative - creating the new machines, technology and people needed to manufacture tomorrow’s products
The Advanced Machinery & Productivity Initiative will enable invention, realise innovation, and adoption of new machinery and robotics through UK equipment manufacturers. The p...
UK Status, Change and Projections of the Environment (UK-SCaPE)
The UK faces significant challenges in the 21st century due to mounting pressure on air and soil quality, water and food security, and the conservation of biodiversity. To provide...
Improving Communication with Adults with Learning Disabilities (ICALD)
This project addresses two questions: What are the challenges to consistent delivery of communication-focused support for people with learning disability (LD) and severe communicat...
NIHR Global Health Research Group on collaborative care for cardiometabolic disease in Africa
Research question Can a model of care based on the chronic care model (CCM) and collaborative care model (CoCM) sustainably improve cardiometabolic health in low-to-middle income...
Developing a learning health system to address the growing burden of non-communicable diseases in Thailand
Research question: Can a Learning Health System (LHS) approach improve delivery of care and reduce inequalities in outcomes for people with hypertension and related non-communicabl...
The PORTRAIT trial – Post-operative radiotherapy in surgically treated bone metastases
Research question Does post-operative radiotherapy following surgery for pathological fractures improve pain and quality of life? Background Approximately 70% of people with a...
The Epiverse - Distributed Pandemic Tools Program
Covid-19 exposed major gaps in our ability to aggregate and use data for pandemic prevention, detection, and response. Current approaches require pooled data, which is costly, time...
A randomised controlled trial of a facilitated home-based rehabilitation intervention in patients with heart failure with preserved ejection fraction and their caregivers: the REACH-HFpEF Study
AIM To assess the clinical effectiveness and cost-effectiveness of home-based cardiac rehabilitation programme ‘REACH-HF’ plus usual care (intervention) versus usual care alone (c...
institutional Translational Partnership Award: Thailand Major Overseas Programme
MORU has an unparalleled track record in tropical medicine research, with a tangible impact on global health. Despite these successes, not all opportunities to translate our resear...
Initial Management of Pleural infection: Aspiration versus Chest Tube (IMPACT) trial
Background: Parapneumonic pleural effusions develop in up to 50% of patients with pneumonia. The majority will resolve with antibiotic treatment of the underlying infection. Howeve...
Evaluating the implementation of the Transforming Children and Young People's Mental Health Provision Green Paper
Background The Children and Young People’s (CYP) Mental Health Green Paper Programme is an ambitious implementation programme creating mental health support teams (MHSTs) to pr...
Evaluating and responding to the public health impact of no and low alcohol drinks: A multi-method study of a complex intervention in a complex system
AIM: This project aims to characterise, monitor and evaluate the public health impact of efforts to increase the availability and consumption of no- and low-alcohol (no/lo) drinks...
Translational regulation of cerebral cortex wiring
The mammalian cerebral cortex is a highly complex brain structure containing a wide diversity of neuronal cell types interconnected in a remarkably specific manner. The many behavi...
MRC Centre of Research Excellence in Therapeutic Genomics
Genome-targeted therapies, e.g., CRISPR-Cas9, use genetic sequence to target their actions to specific genes, bringing unrivalled specificity. This specificity will revolutionise h...
The clinical and cost-effectiveness of the DESMOND-ID education programme for adults with intellectual disability and Type 2 Diabetes
Research question: Does a diabetes education programme tailored specifically for people with intellectual disability (ID) improve self-management of Type 2 diabetes (T2D) compared...
The clinical benefits and cost-effectiveness and safety of haematopoietic interventions for patients with anaemia following major emergency surgery: a phase IV, multicentre, multi-arm randomised controlled trial: Peri-op Iron and Erythropoietin (EPO) Intervention Study - POP-I
RESEARCH QUESTION In patients 60 years or older recovering from major emergency surgery (P), is treating postoperative anaemia with IV iron (I1), or IV iron + erythropoiesis-stimu...
A multi-centre randomised controlled trial of the clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury
RESEARCH QUESTION What is the clinical and cost-effectiveness of a selective serotonin reuptake inhibitor (SSRI) for preventing depression following traumatic brain injury? BAC...
ATHENA: AmiTritypline for the prevention of post-HErpetic NeuralgiA
Background: ~20% of people with Herpes Zoster (HZ, “shingles”) develop post-herpetic neuralgia (PHN). The pain can be difficult to treat and has a substantial impact on the quality...
The Healthy Reproductive Ageing (HERA) Study
Reproductive health in women is under-researched and the field lacks key experimental tools and resources to advance biological understanding. Human genetic approaches have identif...
Randomised controlled trial of the Community Navigator programme to reduce loneliness and depression for adults with treatment resistant depression in secondary mental health services
Background: Clinical outcomes are poor for people with Treatment Resistant Depression (TRD); existing medical and psychological treatments have limited benefit. Loneliness predicts...