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15,626 grants found
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Chronic obstructive pulmonary disease and heart failure insights from cardiovascular imaging
Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide and is frequently associated with heart failure with preserved ejection fraction (ass...
What are the mechanisms behind negative effects of vaccination on growth in fish?
The aim is to contribute to economically, ethically and environmentally sustainable fish aquaculture through more effective vaccination methods with decreased side effects, and tha...
Translational molecular imaging in Alzheimer´s disease and other neurodegenerative proteinopathies
The proposal has a translational approach using in vitro and in vivo imaging techniques to obtain a deeper understanding of the early pathological disease mechanisms and complex ca...
Green Carbon Black
Carbon Black (CB) is a man made, paracrystalline form of carbon, and one of the most widely used carbon-based industrial chemicals made today from incomplete combustion of heavy, f...
Making the Sustainable Development Goals Real: the Role of Emerging Media in Sustainability Transformations
The digital revolution is propelling innovative media forms that are fundamentally changing how we understand the world, communicate, engage and imagine the future. At the intersec...
The significance of environmental and lifestyle factors for the onset and course of multiple sclerosis.
Multiple sclerosis (MS) is the leading cause of non-traumatic neurological disability in young adults in Europe. The etiology is unclear. Twin studies suggest that environment and/...
Developing the use of remote sensing data in safety planning
The way we build, monitor and maintain cities impacts critically on how safe they are for their citizens. Current methodologies used to obtain information about the urban environme...
Inflammatory bowel disease and risk of cancer - a moving target in an age of new targeted therapies
What (purpose and aim)To quantify how risk of and mortality from major malignancies in IBD (e.g., colorectal cancer [CRC], small bowel cancer, lymphoma, liver cancer, pancreatic ca...
Multi-pronged approach for early diagnosis and prognosis of COPD
We will use a multi-pronged approach for two aims: early identification of individuals at risk of developing chronic obstructive pulmonary disease (COPD) and identification of subj...
Chemistry of Short-Lived-Climate-Forcers in the Indo Gangetic Plains and Himalayas:Implications for hydrological cycle, agriculture and sustainable development in a changing global climate
The Indo Gangnetic plain (IGP) covering Pakistan, India, Bangladesh, (including Himalayan countries, i.e. Bhutan and Nepal) is exposed to one of the most severe regional air pollut...
A longitudinal approach to characterize loss of muscle mass and function in aging humans – the importance of peripheral nerve integrity
The loss of skeletal muscle function and mass is a key component underlying disability and morbidity in the steadily growing elderly population. Another important, yet often neglec...
Loss of chromosome Y causes defective immune-surveillance, which leads to cancer and Alzheimer’s disease in aging men
We recently made three discoveries related to acquired Loss Of chromosome Y (LOY) in blood of adult/aging men. LOY is associated with: a) shorter survival and increased mortality f...
Transcriptional enhancers in human neuronal development and the brain
The human genome contains more than 100,000 enhancers, regulatory elements along the DNA that fine-tune gene expression. We will now pioneer the identification of new enhancer elem...
Investigating the potential of combination therapies targeting the cholinergic system in Alzheimer´s disease
The complexity of Alzheimer´s disease (AD) must be addressed targeting different mechanisms. Since the cholinergic system is degenerating in the early days of AD, is the persisting...
Identification of protein-profiles to characterise pre-clinical phases of inflammatory bowel disease and to predict the disease (PreClin-IBD)
What (Purpose and Aim) To define the early stages of inflammatory bowel disease (IBD) development, I will identify pre-clinical phases of IBD based on protein profiles and examine...
Novel therapeutics for bone growth disorders targeting the growth plate
PURPOSE AND AIM: Abnormal bone growth is a very common problem. Many children with chronic diseases have impaired bone growth, others have leg length differences, or in rare cases...
Innovative Slag design for eco-friendly efficient recycling of spent LIBs _InnoSlag4LIB
The dominating technology for spent Li-ion batteries (LIBs) recycling in EU is based on combined pyro and hydrometallurgy with focus on recovery of valuable metals like Co, Ni etc....
Imidazole propionate- a novel link between the human gut microbiota and development of insulin resistance in adipose tissue.
The gut microbiota affects numerous biological functions in the human body, and this has become an important field of research in biomedicine. Gut bacteria play a fundamental role...
Secondary mobilization: The spread of political violence within and across borders
Why are some civil wars and terrorist campaigns more devastating across time and space than others? Scholars have found the number of different actors involved matters, but we know...
Making the Medieval World. The Metaphysical Foundations of Social Groups in Late Medieval Philosophy
In contemporary philosophy there is an animated discussion on the nature and origin - the metaphysical foundations - of social groups such as states, corporations, associations, bo...