Results for Health
130,725 grants found
Showing 128,701 – 128,720 of 130,725 grants for "Health"
Interdisciplinary Center of Excellence for the Study of Pain and Sensory Function
Chronic pain continues to be a critical health, social and economic issue throughout the world. Patient relief is undermined by modest efficacy and/or serious, self-limiting side...
OPUS: A Career in Cycad Biology: An e-monograph
In the plant tree of life, a group of plants of special interest are the cycads. The cycads are widely considered the world’s most endangered plants with most of the 380 living spe...
Novel Function(s) of Arenavirus NP Exoribonuclease
PROJECT SUMMARY/ABSTRACT Several mammalian arenaviruses cause severe and fatal zoonotic diseases in humans, for which vaccines and treatments are very limited. Lassa virus (LASV)...
Novel Function(s) of Arenavirus NP Exoribonuclease
PROJECT SUMMARY/ABSTRACT Several mammalian arenaviruses cause severe and fatal zoonotic diseases in humans, for which vaccines and treatments are very limited. Lassa virus (LASV)...
Research Project 1: Coronavirus antiviral lead development and combination testing
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of COVID-19 has profoundly impacted global human health and shown that it is imperative...
Aerosol Ventilation for Rapid Cooling of Transplant Donor Lungs
PROJECT SUMMARY Over 2,700 lung transplants are performed in the US each year, but a significant shortage of donor lungs means that thousands of people die each year while waitin...
Reaching Equity in ACess to Home Dialysis And Re-Transplantation (REACH-DART)
PROJECT ABSTRACT Kidney transplantation and home dialysis are the preferred treatment modalities for end-stage kidney disease (ESKD) given the better quality of life and lower co...
Reaching Equity in ACess to Home Dialysis And Re-Transplantation (REACH-DART)
PROJECT ABSTRACT Kidney transplantation and home dialysis are the preferred treatment modalities for end-stage kidney disease (ESKD) given the better quality of life and lower co...
Evaluation of oral administration of PRIM-DJ2727 capsule containing microbiota suspension in patients with severe alcoholic hepatitis: An Open-Label Study
Alcoholic hepatitis (AH) is a major public health problem in the United States, in which 30-50% die within the first 28 days. For the past few decades, steroid therapy has been th...
Polo-like-kinase-2-dependent α-Synuclein Serine-129 Phosphorylation: a Physiological RoleDuring Synaptic Activity
SUMMARY/ABSTRACT Parkinson’s disease (PD), dementia with Lewy bodies (DLB), multiple-system atrophy (MSA) and certain forms of Alzheimer’s disease (AD) are ‘synucleinopathies’ -...
Tetrafluoro(trifluoromethyl)sulfanes Chemical Reactivity and Polar Hyrdophobicity
With the support of the Chemical Structure, Dynamics, and Mechanisms B (CSDM-B) Program in the Division of Chemistry, Professor John T. Welch of the University at Albany, will inve...
RUI: A Mosaic Model of Host-Microbe Thermal Relationships
Ectothermic vertebrate animals, such as fish, amphibians, and reptiles, show both adaptation to temperature in their environments and the ability to acclimate to changes in those t...
Bridging clinical trial and real-world data via machine learning to advance rheumatoid arthritis treatment strategies
PROJECT SUMMARY/ABSTRACT Rheumatoid arthritis (RA) is the most common autoimmune joint disease with over 15 treatment options, reflecting both advances in therapy as well as the...
Mechanisms of disordered citrate and oxalate excretion in nephrolithiasis
Project Abstract Kidney stones are a major cause of morbidity and account for $11 billion in health care spending in the U.S. Low urine citrate and high urine oxalate both increa...
Collaborate2Lose: Collaborating with romantic and non-romantic support persons to improve long-term weight loss
Background: Over 40% of Veterans have obesity, a risk factor for multiple chronic diseases. Weight loss interventions produce clinically significant weight loss, yet weight regain...
Helping Veterans Navigate Dual Pharmacy Benefits
Background: Nearly 30% of Veterans with diabetes dually use Medicare Part D and VA to fill their antidiabetic medications, and dual users have poorer glycemic control and poorer...
Senior Research Career Scientist
Abstract: The Veteran population is skewed in terms of age, with more than 55% of Veterans already over 65 years of age. Older individuals with deficits in muscle size, strength...
VZV vaccine attenuation and the DNA damage response
ABSTRACT Diseases caused by the human herpesvirus Varicella Zoster Virus (VZV) are widespread and debilitating but can be limited by using live attenuated VZV vaccines. The varic...
A Novel High Intensity Short Interval Dance Intervention for Non Communicable Disease(NCD) Prevention in Asian Indian Adolescent Girls-THANDAV
A Novel High Intensity Short Interval Dance Intervention for Non Communicable Disease (NCD) Prevention in Asian Indian Adolescent Girls - THANDAV - a pilot study. This proposed dev...
Role of antigen valency and pattern recognition receptor ligands in HPV vaccine-induced durable B cell memory
ABSTRACT Most vaccines protect by generating antibodies. Live attenuated vaccines induce lasting humoral immunity; however, humoral immunity for many subunit vaccines wanes over...