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199,248 grants found
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Learning to see; The brain as the next frontier in sight rescuing regenerative therapy
This program investigates the mechanisms of neuroplasticity essential for sight rescue after regenerative therapy.After decades of research on revolutionary ocular therapies but on...
Mechanisms of symmetry breaking at molecular and cellular scales in planar polarity
Symmetry breaking in biological systems is fundamental for pattern formation and elaboration of organismal complexity.In this proposal we seek multi-scale understanding of the symm...
Medicine without Doctors: Reimagining Care and Voice Through Play
Medicine without doctors is now a possible and plausible future for healthcare.Already encroached upon by commercial and scientific stakeholders, doctors’ roles in the UK have rece...
CAMMISA: Climate-focused Analytics and Modelling for Mosquito-borne Infections in Southern Africa
The widespread manifestation of climate change with trends in seasonality and extreme climate events have important implications for Mosquito-Borne Diseases (MBD).The transmission...
Disentangling a new paradigm for mutual homeostasis of aggregation-prone proteins
The dosage of proteins must be regulated in cells, especially for those containing low complexity domains (LCD-proteins) due to their propensity for condensation and aberrant aggre...
ENTHUSE – EvaluatiNg The High fat sUgar Salt rEgulations: practice, response and impact across retail settings
Background: Obesity and poor diet constitute two of the greatest threats to population health.The UK government introduced world-first Food (Promotion and Placement) regulations in...
Health, socioeconomic, and environmental risk factors for heat-related mortality and hospital admission in England
Background Climate change is causing increasingly frequent and intense heat events worldwide.In England, we are already witnessing the impact of extreme heat on population health,...
Investigating the multiple roles of cryptochromes in animal magnetoreception
Many species, including humans, are reported to be magnetosensitive. Indeed, some animals navigate using the weak magnetic field (MF) of Earth.Others do not, but there are accounts...
Data as a foundation for AI innovation and global discovery research in the life sciences
EMBL-EBI's data resources are a fundamental necessity for biomolecular research.Through open data, there is tremendous potential for accelerating scientific understanding and...
Understanding and manipulating stress signalling: from mechanisms to therapeutics
Numerous stress-signalling pathways are required to ensure cell survival in the face of challenges.My lab aims at identifying strategies that harness these signalling pathways to e...
How do phagocytes control phagosome fate and pathogen killing?
Our goal is to understand how phagocytic cells control how they kill different microbes.This core role of immune cells is key to preventing infections, but how pathogen processing...
Mainstreaming ethics in policy and research: from capacity to translation
The experience of the COVID-19 pandemic has reinforced the urgent need for global leadership in supporting and enabling context-sensitive ethical expertise in policy making and res...
Unravelling the lipid landscape in lysosomal storage disorders and associated Parkinson's disease: insights for drug discovery
Genetic variants in lysosomal sphingolipid (SL) genes cause lysosomal storage disorders (LSDs) and are strongly linked to Parkinson’s disease (PD) risk.In addition to the lysosomal...
AMEND - eArly Modern European NeuroDivergence
This project will significantly shift the understanding of what we currently call neurodivergence by investigating the analogous concept(s) used by early modern people.Establishing...
Yes, I do: A theory on belligerent consent to United Nations peace missions
Mediation / Good offices
Mykhailo Drahomanov: Switzerland on Ukraine's Intellectual Map of Europe
Nationhood
Improving sex and gender documentation in Swiss medical records for REspectful and Accessible Care and Health for trans and non-binary people (GENDER-REACH)
Sexual characteristics
Amazonian BioTechQuilombo - Amazonian Biodiversity, Technology Assessment and Exchange Knowledge with Quilombos
fish
Unravelling innate immune adaptations in neuroinflammation (MINE)
neurodegeneration
Robustness, Causality and External Validity of Statistical Machine Learning, with applications in Digital Health
Uncertainty quantification