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199,248 grants found
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Timing the Economic, Cultural and Environmental patterns of Agropastoralism development in the Indo-Iranian Borderlands
The emergenceThe emergence of an agropastoral way of life in South West Asia from the late 10th millennium BCE revolutionised the social organisation of prehistoric communities. Th...
Critical Geopolitics of Nuclear Fuel Supply in Europe
How do countries build their nuclear fuels supply policies?The ongoing political renaissance of nuclear power through the world raises concerns about European Union states ability...
Harnessing RARA signalling for curative AML therapies
In acute promyelocytic leukaemia (APL), retinoic acid (RA) and arsenic trioxide (ATO) bind the PML/RARA fusion to promote its degradation, derepressing unknown master regulatory ge...
Understanding the molecular basis of protein folding disorders and protein quality control in muscle
Mutations in certain proteins can cause their misfolding and aggregation, posing a potential threat to the health of an organism.Protein aggregation is counteracted by protein qual...
Chiral phononics: Controlling electronic phases with phonon angular momentum
This projects aims to establish a new paradigm in the ultrafast control of solids, by using the angular momentum of chiral lattice vibrations (chiral phonons) to manipulate, induce...
Dissecting the Functional Role of Mucosal IgA Clonal and Glycoprofiles for Effective Humoral Mucosal Protection
Numerous mucosal vaccines and IgA-based monoclonal antibodies aimed at a robust immunity within the respiratory tract are in development to combat viral endemics and pandemics.Howe...
Mitochondrial Strategies in Ferroptotic Cell Death
Mitochondria serve as the epicenter of cellular metabolism. Their dynamic communication with other compartments within the cell ensures proper cellular function.My recent work reve...
Moving Bodies and Memories of African Slavery in South America
The MOVING project is aimed at developing an ethnographic and multi-disciplinary methodology to study the bodily traces of Africa-originated slavery enduring in post-slavery and di...
Recreating molecular memories: imaging the mechanics of chromosome assembly and the birth of cell identity
The gene expression patterns that define specific cell types are determined in part by epigenetic information encoded in histone marks that guide chromatin organization.During chro...
Understanding and designing inorganic materials properties based on two- and multicenter bonds
A major challenge for the green transition is our inability to rationally design inorganic materials with tailor-made properties.This project will tackle this inability by transfor...
Keyless Cryptography for Efficiency and Security
Cryptographic primitives are the foundation of security in any secure information system.Permutations and similar keyless cryptographic primitives have risen to great popularity in...
Hazard sensors based on holographic metasurfaces for near eye augmented reality displays
Augmented reality (AR) technology is uniquely positioned in the tech landscape, offering the ability to overlay digital information directly onto the physical world, distinct from...
Challenges in Competitive Online Optimisation
Online decision-making, characterized by the need to make decisions without knowledge of the future, lies at the heart of numerous applications. Despite its prevalence, our grasp o...
Information Economics With Fundamental Uncertainty: Robustness, Commitment, and Strategic Incentives
Many pivotal decisions hinge on navigating fundamental uncertainty, where a comprehensive description of the relevant contingencies and exact odds remains elusive. This project exp...
How dividing cells adapt to karyotypic evolution
Alterations in chromosome number and size are hallmarks of cancer, and yet they are also crucial for species evolution.Recent insight on chromosome structure and segregation, toget...
Carbon-Hydrogen bond activation via a new charge control approach
Organic synthesis stands as the beating heart of technological and societal advancement, driving breakthroughs in drug discovery, agrochemistry, materials design, and the pursuit o...
Spatial Metabolic Regulation in Kidney Repair
Chronic kidney disease (CKD) is a global health concern, and the limited treatment options for end-stage kidney disease have remained unchanged for decades.Concurrent insults to th...
Egalitarian but not Equal: Sectoral Wage Formation and Gendered Wage Differentials
All over the globe, women in the work world receive, on average, 20% less than their male counterparts (United Nations, 2022).In countries explicitly committed to eliminating the g...
Edible lasers for safety and authentication of food and pharmaceuticals
The goal of EdibleLasers is to make microlasers entirely out of edible materials and explore their potential for barcoding and sensing in food, pharmaceuticals and beyond.In the on...
Dynamic control of Gaussian morphing structures via embedded fluidic networks
Transforming a flat plate into a doubly curved shell is not possible without distorting in-plane distances, as stated by Gauss in his seminal theorem.In natural morphogenesis, this...