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Combinatorial neuromodulation of internal states
Being sleepy, hungry, afraid, or happy impacts our daily experience and defines our behavior and actions.Such internal states are characterized by unique signatures of activity acr...
Wood-Derived Hybrid Particles for Stabilized Dispersions
Aqueous particle dispersions are elemental to many aspects of every-day life, from food and pharmaceuticals to construction materials.However, todays dispersion science faces a gra...
Deep-sea carbonates under pressure: mechanisms of dissolution and climate feedbacks
As humanity grapples with the escalating crisis of climate change, understanding and mitigating the sources of carbon dioxide (CO2) emissions is imperative.A lesser-known yet signi...
THRON-SEC: Drug-Induced Secretome Profiling for Enhanced Therapy
Under normal conditions, cells release proteins (secretome) to regulate fundamental processes like metabolism and immunity.Many diseases and their corresponding treatments involve...
Optimal Local Algorithms via Topology-Sensitivity
Considering the rapid growth of data sets and network sizes over the past decade, there is little doubt that the future of computation is distributed.One central aspect lying at th...
Cognitive and Neural Computations of Semantics
In our everyday lives, we rely on existing relations among elements in our environment (i.e., semantic information) to interact efficiently with the world.This information can eith...
Leveraging Polymer Therapeutics as Nanomedicine for Local Glioblastoma Immunotherapy
Research focusing on cancer immunotherapy has provided little progress toward improved survival rates for patients with glioblastoma (GBM), a poorly immunogenic tumor.Clinical tria...
Intensity Correlations for Stars
The pioneering experiments of intensity correlations by Hanbury-Brown and Twiss more than 50-years ago not only allowed to measure the angular diameter of many bright stars, but it...
Overcoming limits for pre-clinical small volume liquid delivery into skin and inflammation quantification
Chronic inflammatory skin diseases have a huge burden on patients, their families, and the economy. New patient-friendly delivery methods are urgently needed targeting immune cells...
Harnessing Specialized Metabolism from Anaerobes
Anaerobic bacteria, a group of microorganisms that thrive in the absence of oxygen, have a significant impact on the quality of life on Earth. They play a crucial role in biotechno...
Massive-binary EvoluTion Across the metallicity Ladder
Do massive stars undergo supernova explosions when collapsing into black holes? What mechanisms drove the Cosmos into an epoch of reionization? How was dust produced in the Early U...
Fluid gap Electro-Active-Polymer machines for a new generation of mechatronic systems
While mechatronic solutions become increasingly pervasive, there are areas, such as the space or the ocean depths, that are still difficult to reach and exploit through conventiona...
Transition from Transport Reindeer Herding to Reindeer Pastoralism: A study of Indigenous Governance during Change
Aboriginal societies around the world have independently transitioned their production mode.In northern Eurasia, the transition manifested itself in a movement away from transport...
Health, Cognition, Family, and Employment among Men
Men are more likely than women to die prematurely, and a great deal of men’s excess mortality is preventable.Improving men’s health and cognition is not only critical for achieving...
Engineering soft microdevices for the mechanical characterization and stimulation of microtissues
As living beings move, touch, or grow, the tissues within them are subject to mechanical stresses that act over minutes, hours, or days.These efforts play a critical role at all st...
(Re-)Writing the Ubiquitin Code – Manipulating Polyubiquitin Chain Linkage to Investigate Ubiquitin Signalling in Genome Maintenance and Beyond
Ubiquitylation is an essential posttranslational modification that governs the activities and interactions of cellular proteins.The structural diversity of polyubiquitin chains, co...
Tuning Heat Transport in 2D Materials with Defects
The unstoppable race towards miniaturization is pushing the limits of electronics.This has to be conciliated with the inevitable Joule heating that affects all electronic devices,...
Metal-Organic REagents for Light-Enabled Shuttling of protons and electrons
Protons and electrons are the currency of energy conversion and play a key role in some of the most transformative technologies such as the reduction of N2, CO or CO2.Exploiting wa...
Skills Markets: Marriage and Labor
The distribution of workers across jobs and across different geographic areas has major implications for growth, social welfare and inequality.It is complex but essential to unders...
The impact of human aged bone marrow niche on human hematopoietic stem cell function
In humans, aging of the hematopoietic system is associated with anaemia, impaired immune responses and increased frequency of myeloid malignancies. The hematopoietic system is main...