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199,248 grants found
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Understanding and targeting pathogenic IgG4 responses
The predominant autoantibody (sub)class is an important determinant in the pathophysiology of autoimmune diseases (AID).Autoantibodies can be pro-inflammatory, such as IgG1, causin...
The interplay of symbiont nutrient release and host phagosome maturation in photosymbiosis regulation
Photosymbioses between heterotrophic hosts and phototrophic algal endosymbionts have repeatedly and independently evolved across the tree of life.The immense productivity of photos...
The Geopolitics of Cloud Computing: How State-Firm Interactions Shape the Geography of Computation to Produce Digital Sovereignty and Dependence
Today’s digital superpowers, the United States and China, exploit other countries’ reliance on their digital infrastructures for foreign policy and national security advantage.Gove...
Probing and controlling ultrafast electron and ion dynamics in operating battery electrodes and interfaces
Charge dynamics lie at the crux of electrochemical energy devices, and in-particular batteries, impacting everything from durability to capacity.On mesoscopic time (ns to s) and le...
Unpacking confined lives: Generating a global research agenda on the intersection of urban marginality, displacement, and incarceration
CONFINED will develop and validate an innovative, comparative, and global research agenda of confined lives. Confinement is a ubiquitous and unequally distributed human condition.W...
A Statistical Mechanics Framework for Immiscible Two-Phase Flow in Porous Media
The flow of immiscible fluids in porous media is at the heart of a wide range of applications, some of which are central to humanity.Oil recovery has traditionally had such a role,...
Force-free microstructures host intrinsic dynamics of orbital phases in AV3Sb5 Kagome metals
Electron correlations significantly modify electron self-organization in quantum materials, resulting in a landscape of competing orders and exotic quantum phenomena.The recently d...
ILLUMINATING ROUTES TO 3D ORGANOBORON MOLECULES
With a steadily growing, aging population, there is significant strain on the pharmaceutical sector to produce state of the art therapeutics for societal needs whilst respecting th...
Beyond compliance: Rethinking the Effectiveness of Regional Human Rights Regimes
The European, African and inter-American human rights regimes seem not to be effective vis--vis non-democratic states. Besides undermining the international rule-based order, this...
Neutrino flavor Transformations in dense Astrophysical Environments
This project NeuTrAE is aimed to advance our understanding on lingering puzzles on the flavor evolution of neutrinos and their implication in particle and nuclear astrophysics.Neut...
Active Inference and the Circuits of Precision and Prediction
The human brain exhibits remarkable cognitive abilities, such as imagery, attention and mental simulation, which along with perception reflect our capacity to infer properties of t...
Revolutionizing diabetes management by combining in silico models and AI control for vagus neuroprostheses
Diabetes is a major world health problem, approaching epidemic proportions and causing long term health damages due to inappropriate blood glucose regulation.Pharmacological therap...
Asymptotic analysis of repulsive point processes and integrable equations
The purpose of this project is to apply and develop robust mathematical methods for solving asymptotic problems on repulsive point processes and partial differential equations.The...
Circadian structural transitions of chromatin
Transcription factors (TFs) distinctly mark regions of the genome for expression and are the pillars of cell identity. Yet, even at the basic level of DNA recognition by TFs, we kn...
Formation, Clustering, and Atmospheric Impact of Clusterable Organic Compounds
Atmospheric aerosol particles have a critical impact on Earth’s radiative balance and human health. Oxygenated organic molecules play an important role in the formation and growth...
Quantum Probes for High-Pressure Superconductivity
Materials under high pressure exhibit exciting topics such as the superconductivity (SC) of hydrogen-rich molecular compounds (super-hydrides) in the long standing search of room-t...
Future-Proof Data Systems in the Post-Moore Era
Three major trends put immense pressure on existing infrastructure. First, there is an increased demand for compute given the exponential growth of data volume we are collecting. S...
Tracing Visual Computations from the Retina to Behavior
Every second, millions of bits of information enter our eyes. How does the brain identify task-relevant information from this gigantic input stream?This key challenge of the visual...
Advanced analysis of multiparametric volumetric ultrafast ultrasound: a novel approach for non-invasive breast cancer diagnosis
Tumour development follows a diversity of complementary biological pathways, including the modification of the tissue structure and vascularization, which are not currently capture...
The elusive role of physicality in virtual trials: Towards a new understanding of legal participation
Video links are widely used in courtrooms across the globe but there is a mounting apprehension that the legitimacy and fairness of trials are threatened by the diminishment of phy...