Results for Technology
53,864 grants found
Showing 49,761 – 49,780 of 53,864 grants for "Technology"
Developing and Applying Analytical Models of Influenza Transmission
Our current scientific knowledge indicates the importance of influenza transmission via exhaled viral bioaerosols over short and long ranges in indoor environments.The turbulent na...
Targeting added sugar to improve dietary intake in high-risk adolescents
PROJECT ABSTRACT The overall goal of this K01 proposal is to provide Gina Tripicchio, PhD, MSEd, with the training and mentorship to establish an independent program of research fo...
Image-guided, robot-assisted reduction of joint dislocation in orthopaedic surgery
PROJECT SUMMARY / ABSTRACT Surgical treatment of joint fractures and dislocations following orthopaedic trauma requires accurate reduction and fixation of the joint space to restor...
Integration of multimodal cancer predisposition genetic counseling practices within the pediatric oncology setting
PROJECT SUMMARY Recent advances have led to a rapid increase in the testing and identification of cancer predisposition in children.There is growing evidence that ?15% of childhood...
Circular mimics of Iron-response elements to inhibit ferroptosis
SUMMARY: Iron overload is found in nearly all patients with Parkinson's disease and can lead to ferroptosis, an iron-dependent form of cell death.The importance of iron in Par...
SUCCEED Pilot Project 2
PILOT PROJECT 2: PROJECT SUMMARY The NCI Screen to Save (S2S) has successfully increased awareness about colorectal cancer (CRC) and the importance of screening for prevention and...
Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy
Program Summary While altered cell metabolism is emerging as a hallmark of cancer, there is an unmet need for new tools for quantitation of metabolites. NMR spectroscopy, mass spec...
Cancer Biology Research Test-Bed Unit 1: Effects of cell-intrinsic and cell-extrinsic signaling and mechanics on metastasis patterns of pediatric sarcomas
Ewing sarcoma, a malignant tumor of bone and soft tissue affecting children, adolescents, and young adults. For the one-third of Ewing sarcoma patients who develop metastasis, the...
Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy
Program Summary While altered cell metabolism is emerging as a hallmark of cancer, there is an unmet need for new tools for quantitation of metabolites. NMR spectroscopy, mass spec...
SUCCEED Pilot Project 2
PILOT PROJECT 2: PROJECT SUMMARY The NCI Screen to Save (S2S) has successfully increased awareness about colorectal cancer (CRC) and the importance of screening for prevention and...
Plasticity of cortical circuits in health, aging, and Alzheimer's disease
Project Summary/Abstract Comprised of six distinct layers, the cerebral cortex is the key brain structure for all of our cognitive abilities, ranging from sensation to decision mak...
SUCCEED Pilot Project 2
PILOT PROJECT 2: PROJECT SUMMARY The NCI Screen to Save (S2S) has successfully increased awareness about colorectal cancer (CRC) and the importance of screening for prevention and...
Small molecule inhibitors of hyperphosphorylated tau aggregation and cytotoxicity for the development of Alzheimer’s therapeutics
PROJECT SUMMARY Neurodegeneration in Alzheimer's disease (AD) is increasingly accepted to result from the toxicity of hyperphosphorylated tau aggregates, the major constituent...
A Novel RNA Therapeutics Platform to Treat Facioscapulohumeral Muscular Dystrophy and other Neuromuscular Disorders
Abstract: In this Fast Track SBIR application miRecule proposes to develop a muscle-specific platform (Muscle-NAVTM) for the delivery of therapeutic oligonucleotide to treat inheri...
Image-guided, robot-assisted reduction of joint dislocation in orthopaedic surgery
PROJECT SUMMARY / ABSTRACT Surgical treatment of joint fractures and dislocations following orthopaedic trauma requires accurate reduction andfixation of the joint space to restore...
Identification of new therapeutic targets for ADPKD
Autosomal-dominant polycystic kidney disease (ADPKD) affects more than 12 million people worldwide and is a common cause of end-stage kidney disease (ESKD). ADPKD is caused by muta...
Midcareer investigator award in patient-oriented research in the area of perinatal-developmental neuroscience
Despite evidence that 1 in 5 children are at risk for psychiatric disorders, only 1 in 20 young children receive mental health care. Thus, a high number of children who would benef...
CHOICES for Sickle Cell Reproductive Health: RCT of a Preconception Intervention Model for a Single Gene Disorder
Project Summary/Abstract Our long-term goal is to foster genetically-informed reproductive health knowledge and behaviors among young adults with sickle cell disease (SCD) or sickl...
Prediction of Heart Failure Onset using Multimodal Data Analysis, Deep Learning and Commercial Wearables
Prediction of Heart Failure Onset using Multimodal Data Analysis, Deep Learning and Commercial Wearables Project Summary/Abstract Research: Heart failure is one of the leading caus...
Digital Biomarkers of Ulcerative Colitis Flare
This project will evaluate longitudinally collected physiological metrics, with a focus on autonomic nervous system function (heart rate variability [HRV]), using wearable devices....