Results for Technology
53,864 grants found
Showing 49,641 – 49,660 of 53,864 grants for "Technology"
Development of a non-invasive method to monitor expression and function of optogenetic tools in non-human primates
PROJECT SUMMARY Optogenetic methods have been used extensively to expand our knowledge of the normal and pathological roles of the basal ganglia and related brain areas involved in...
A Preclinical Study Evaluating and Comparing the Efficacy of Tissue Engineered Vascular Grafts to Polytetrafluoroethylene Grafts
PROJECT SUMMARY Tissue engineering provides a strategy for developing improved prosthetic biomaterials for use in congenital heart surgery. The overriding premise of our work is th...
Addressing Hearing Loss as a Common Unmet Contributor to Neuropsychiatric Symptoms
PROJECT SUMMARY As the number of adults age 65 and older continue to increase, the prevalence of Alzheimer’s disease and other related dementias (ADRD) is also expected to increase...
A Preclinical Study Evaluating and Comparing the Efficacy of Tissue Engineered Vascular Grafts to Polytetrafluoroethylene Grafts
PROJECT SUMMARY Tissue engineering provides a strategy for developing improved prosthetic biomaterials for use in congenital heart surgery. The overriding premise of our work is th...
Accelerating radiopharmaceutical discovery and development via high-throughput radiochemistry
PROJECT SUMMARY The continuous discovery of new biological targets presents opportunities to dramatically improve our understanding of diseases and normal function and provides new...
Nanoparticles for In Vivo Labeling of T Cells During Cancer Immunotherapy
Project Summary Despite decades of research, the prognosis for patients with malignant brain tumors remains poor and novel treatment strategies are urgently needed. Malignant gliom...
Synthetic Adhesome Cells: Engineering Interfaces Between Synthetic and Live Cells for Controlled Delivery
Multicellular organisms represent a remarkable transition in evolution, wherein single cells began working together to form a cohesive and coherent unit known as tissue. This trans...
ASBMB Interactive Mentoring Activities for Grantsmanship Enhancement (IMAGE 2.0)
While data from the National Science Foundation (NSF) have demonstrated a doubling in the number of underrepresented minorities (URM) in science, technology, engineering, and mathe...
Plasticity of cortical circuits in health, aging, and Alzheimer's disease
Project Summary/Abstract Comprised of six distinct layers, the cerebral cortex is the key brain structure for all of our cognitive abilities, ranging from sensation to decision mak...
Quality and Safety Monitoring of Clinical Computed Tomography Practice
Abstract ?Fifty percent of radiation exposure to the United States population is from medical imaging, half of which come from over 80 million computed tomography (CT) scans perfor...
Mechanisms and effects of pallidal deep brain stimulation on levodopa resistant motor signs in Parkinson's disease
Project Summary/Abstract A large percentage of people with Parkinson’s disease (PD) will develop debilitating levodopa-resistant impairment in postural stability and gait disturban...
Treatment and prevention of osteoarthritis with an intra-articular disease-modifying regenerative therapy
Abstract Nearly one in every ten Americans, and one in every three over the age of 65-years, suffers from osteoarthritis (OA), a degenerative joint disorder that causes progressive...
Development of an Innovative Vervet (Chlorocebus aethiops sabaeous) Model of Early Alzheimer’s-like Neuropathology and Symptomatology
This application is a Supplement to R24 AG073199 Development of a Vervet Model of Early AD-like Neuropathology & Symptomatology. The purpose of this supplement is to: A) exploi...
Clinical Decision Support Tool to Assess Risk and Prevent Agitation Events
PROJECT SUMMARY/ABSTRACT This award is a four-year plan to support Ambrose Wong, MD, MSEd, an emergency physician, in his transition towards an independent research career that foc...
Clinical Decision Support Tool to Assess Risk and Prevent Agitation Events
PROJECT SUMMARY/ABSTRACT This award is a four-year plan to support Ambrose Wong, MD, MSEd, an emergency physician, in his transition towards an independent research career that foc...
Stretching their Reach: Robotic Support for Older Individuals with Mild Cognitive Impairment, Early Alzheimer's Dementia, and Mobility Impairments
Abstract Assistive robots have the potential to enhance individual autonomy, reduce human burden, and lower healthcare costs associated with mild cognitive impairment (MCI), Alzhei...
Clinical Decision Support Tool to Assess Risk and Prevent Agitation Events
PROJECT SUMMARY/ABSTRACT This award is a four-year plan to support Ambrose Wong, MD, MSEd, an emergency physician, in his transition towards an independent research career that foc...
Clinical Decision Support Tool to Assess Risk and Prevent Agitation Events
PROJECT SUMMARY/ABSTRACT This award is a four-year plan to support Ambrose Wong, MD, MSEd, an emergency physician, in his transition towards an independent research career that foc...
Stretching their Reach: Robotic Support for Older Individuals with Mild Cognitive Impairment, Early Alzheimer's Dementia, and Mobility Impairments
Abstract Assistive robots have the potential to enhance individual autonomy, reduce human burden, and lower healthcare costs associated with mild cognitive impairment (MCI), Alzhei...
Digitization TCN: Collaborative Research: Bringing Asia to digital life: mobilizing underrepresented Asian herbarium collections in the US to propel biodiversity discovery
Asia is the largest continent on Earth, and includes the world’s tallest mountains, lowest landscapes, and habitats ranging from arctic tundra to tropical rainforests and mangroves...