Results for Technology
53,864 grants found
Showing 49,561 – 49,580 of 53,864 grants for "Technology"
Novel SETD5-based Molecular Mechanisms and Therapeutic Tools to Understand and Revert Neuronal Dysfunction Associated with Intellectual disability and Autism
PROJECT SUMMARY Autism spectrum disorder (ASD), which is usually accompanied of intellectual disability (ID), is part of a group of neurodevelopmental disorders that are usually di...
Novel SETD5-based Molecular Mechanisms and Therapeutic Tools to Understand and Revert Neuronal Dysfunction Associated with Intellectual disability and Autism
PROJECT SUMMARY Autism spectrum disorder (ASD), which is usually accompanied of intellectual disability (ID), is part of a group of neurodevelopmental disorders that are usually di...
Novel SETD5-based Molecular Mechanisms and Therapeutic Tools to Understand and Revert Neuronal Dysfunction Associated with Intellectual disability and Autism
PROJECT SUMMARY Autism spectrum disorder (ASD), which is usually accompanied of intellectual disability (ID), is part of a group of neurodevelopmental disorders that are usually di...
Novel Polymers of Intrinsic Microporosity for Use as Photonic Materials
Printed electronics is a rapidly growing field, generating a remarkable array of new technologies for lighting, displays, power and sensors. Curved and bendable OLED screens are al...
Head-to-head comparisons of high-performance plasma phospho-tau epitopes for the detection of Alzheimer's disease
Project Summary/Abstract Recent studies suggest that plasma assays for phosphorylated tau protein at threonine 231 (p-tau231), threonine 181 (p-tau181), and threonine 217 (p-tau217...
Frequency domain shortwave infrared spectroscopy (FD-SWIRS) for volume status monitoring during hemodialysis in end stage kidney disease
PROJECT SUMMARY Chronic kidney disease (CKD), or the gradual loss of kidney function, is the ninth leading cause of death in the US and poses an astronomical healthcare burden. CKD...
Head-to-head comparisons of high-performance plasma phospho-tau epitopes for the detection of Alzheimer's disease
Project Summary/Abstract Recent studies suggest that plasma assays for phosphorylated tau protein at threonine 231 (p-tau231), threonine 181 (p-tau181), and threonine 217 (p-tau217...
Flow Acceleration for Stroke Thrombolysis (FAST) System
Acute ischemic stroke (AIS) results from a blood clot in the neurovasculature and is the 5th leading cause of death and 1st leading cause of neurological disability in the United S...
Human T cell Lymphotropic Virus Vaccine development
PROJECT SUMMARY: For this proposal we intend to develop a novel vaccine to prevent and possibly treat Human T cell Leukemia Virus type-1 (HTLV-1) associated diseases. HTLV-1 is a h...
RII Track-4:NSF: DyG-MAP: Fast Algorithms for Mining and Analysis of Evolving Patterns in Large Dynamic Graphs
Graphs (networks) are a versatile scientific framework to represent and analyze biological, social, and human-made complex systems. Such complex systems are inherently dynamic—for...
Collaborative Research: Does responding to stressors prime greater resilience? Testing the long-term effects of challenges on behavior, physiology, epigenetic state, and fitness.
When faced with a major challenge – severe weather, the attack of a predator, an injury – organisms mount a coordinated physiological and behavioral stress response. This response...
Automated ascertainment of bleeding and target lesion revascularization after percutaneous coronary intervention (PCI) using electronic health record (EHR) data
PROJECT SUMMARY Percutaneous coronary intervention (PCI) is the most common cardiac procedure with over 650,000 PCI performed annually in the U.S. Post-PCI complications which occu...
The Roles of Genetically Distinct Cortical Neuron Types in General-Anesthesia- and Sleep-Induced Slow Waves
Project Summary/Abstract. Reversible loss of consciousness is a crucial part of two major medical fields: general anesthesia and sleep. General anesthetics and non-rapid-eye-moveme...
The Roles of Genetically Distinct Cortical Neuron Types in General-Anesthesia- and Sleep-Induced Slow Waves
Project Summary/Abstract. Reversible loss of consciousness is a crucial part of two major medical fields: general anesthesia and sleep. General anesthetics and non-rapid-eye-moveme...
Telehealth Assessment and Skill-Building Intervention for Stroke Caregivers (TASK III)
Project Summary/Abstract: Stroke is a leading cause of serious, long-term disability, and has a very sudden onset. Families are often thrust into providing care without sufficient...
Telehealth Assessment and Skill-Building Intervention for Stroke Caregivers (TASK III)
Project Summary/Abstract: Stroke is a leading cause of serious, long-term disability, and has a very sudden onset. Families are often thrust into providing care without sufficient...
Rapid respiratory microbiological point-of-care-testing in primary care: a randomised controlled trial with internal pilot and qualitative and quantitative investigation of microbial, behavioural and antibiotic mechanisms (the RAPID-TEST RCT)
RESEARCH QUESTIONSClinical: can the use of a rapid respiratory microbiological point-of-care-test reduce same-day antibiotic prescribing in children and adults presenting to primar...
Improving Patient Care Through Objective Monitoring of At-Home Repetitive Ritual Behaviors in Obsessive-Compulsive Disorder
Project Summary Obsessive-compulsive disorder (OCD) is characterized by intrusive, distressing thoughts (obsessions) in response to which an individual feels compelled to perform a...
Phase I clinical trial of adoptive transfer of autologous folate receptor-alpha redirected CAR T cells for ovarian cancer
Abstract Applying CAR T cell therapy to solid tumors such as ovarian cancer (OvCa) is widely considered a major opportunity but also a major challenge and thus the focus of this pr...
Development and Pilot RCT of a Telehealth-delivered Peer Navigation and Coping Skills Intervention to Increase PrEP Uptake and Adherence in Young Black Men who Have Sex with Men
ABSTRACT Young Black men who have sex with men (YBMSM) ages 15-24 are heavily affected by HIV transmission such that, at current rates, it is estimated that about half of Black MSM...