Results for Technology
53,864 grants found
Showing 49,181 – 49,200 of 53,864 grants for "Technology"
THE INTEGRATED DATA ACQUISITION CORE (IDAC)
ABSTRACT FOR IDAC The Integrated Data Acquisition Core (IDAC) of the Aging Adult Brain Connectome (AABC) project will acquire high-quality longitudinal data in the lifespan HCP-Agi...
Extracellular Vesicles as a Link Between Placental and Renal Dysfunction in Preeclampsia
PROJECT SUMMARY Preeclampsia (PE) is a devastating hypertensive disorder of pregnancy that is a leading cause of maternal and fetal mortality and morbidity worldwide. It affects 2-...
Enabling Next Generation Machine Learning for Large Scale Image Analysis
Project Summary/Abstract Deep learning has transformed medical image analysis by delivering clinically meaningful results on challenging problems like prostate cancer detection and...
Using natural language processing and machine learning to identify patients at high risk of potentially preventable carbapenem-resistant Enterobacterales (CRE) infection
Project Summary Carbapenem-resistant Enterobacterales (CRE) cause more than 13,000 infections in U.S. inpatients annually, with mortality rates that can exceed 50%. In hospitals, a...
Supplement to Accelerating photoreceptor replacement therapy with in-vivo cellular imaging of retinal function
To restore high quality, usable vision in patients, it is important to develop regenerative therapies in an animal model that shares key features of the human visual system. The no...
Enabling Next Generation Machine Learning for Large Scale Image Analysis
Project Summary/Abstract Deep learning has transformed medical image analysis by delivering clinically meaningful results on challenging problems like prostate cancer detection and...
Determinants and Outcomes of Age-related Muscle Loss
ABSTRACT / PROJECT SUMMARY The understanding of processes that lead to age-related decline in muscle mass and its consequences has been fundamentally limited by imperfect methods o...
Project 4: Precision Methods for Assessing Brain Health and Age-related Cognitive Impairment
SUMMARY/ABSTRACT: Project 4 Precision Methods for Assessing Brain Health and Age-related Cognitive Impairment and AD Combatting the growing public health and societal burdens assoc...
A Human iPSC-Based Chimeric Mouse Model of Alzheimers Disease in Down Syndrome
Project Summary The goal of our study is to better understand the pathogenic role of human microglia in Alzheimer’s disease (AD) in Down syndrome (DS) and develop new therapeutic a...
Determinants and Outcomes of Age-related Muscle Loss
ABSTRACT / PROJECT SUMMARY The understanding of processes that lead to age-related decline in muscle mass and its consequences has been fundamentally limited by imperfect methods o...
Culturally-responsive community-driven substance use recovery for Black and Latinx populations
Program Summary/Abstract In 2020, over 85,000 people died from drug overdoses in the US, with mortality rates skyrocketing for Black and Latinx people by 140% and 118%, respectivel...
A Novel Radiometry‐Guided Ablation Catheter to Reliably Treat Barrett's Esophagus
ABSTRACT In the fight to eradicate esophageal cancer, Symple Surgical aims to develop a low-cost versatile ablation system for Barrett's esophagus (BE). BE is a serious compli...
Multi-scale, model-driven exploration of sub-generational gene expression in bacteria: individual consequences, population benefits
Research Summary/Abstract Our goal is to decipher how a molecular-level event or property can create heterogeneous behavior within a population, and how this heterogeneity leads to...
Interrogation and Interpretation of Common Fund Data Sets to Identify Novel Ocular Disease Genes
Project Summary/Abstract Inherited diseases are a major source of blindness. These diseases are typically single-gene disorders.Some may cause developmental defects in early eye fo...
Cellular Senescence Network: New Imaging Tools for Arthritis Imaging
Cellular Senescence Network: New Imaging Tools for Arthritis Imaging Senescent cells play a key role in the pathogenesis of major musculoskeletal diseases, such as chonic inflammat...
Strategy for Safe Colon-targeted Local Therapy of Inflammatory Bowel Disease
Inflammatory Bowel Disease (IBD) is a debilitating disease that affects ~70,000 new people every year in the USA. Additionally, IBD increases the risk of developing colon cancer.Du...
Cellular Senescence Network: New Imaging Tools for Arthritis Imaging
Cellular Senescence Network: New Imaging Tools for Arthritis Imaging Senescent cells play a key role in the pathogenesis of major musculoskeletal diseases, such as chonic inflammat...
Open-source computational modeling of Spinal Cord Stimulation (SCS) to enhance dissemination of 1R01NS112996
Project Summary / Abstract (unchanged from original proposal, except supplement in red) There is a need to understand the mechanisms of neural stimulation technologies (RFA-NS-18-0...
Spatiotemporal tools to interrogate O-GlcNAc functions in cellular signaling
Abstract The overall goal of the Fehl laboratory is to develop chemical biology strategies to determine the functional impact of protein modifications during signaling processes. S...
Characterize replication competent myeloid reservoirs in the central nervous system
SUMMARY The eradication of HIV-1(HIV) infection must address all tissues where infection persists. Clearance of infection in the central nervous system (CNS) is not achieved by ant...