Results for Technology
53,864 grants found
Showing 49,021 – 49,040 of 53,864 grants for "Technology"
Development of a brain penetrating single-chain antibody selectively targeting three repeat tau protein as a new treatment for frontotemporal dementia
PROJECT SUMMARY Frontotemporal dementia (FTD) is the most common form of dementia in people less than 60-years of age, and the lifetime risk of developing FTD is 1 in 742. The over...
Leaflet sparing transcatheter aortic valve equipped with IVUS-guided delivery system.
PROJECT SUMMARY/ABSTRACT Transcatheter aortic valve replacement (TAVR) is an essential alternative to surgical aortic valve replacement (SAVR) in elderly patients with aortic valve...
Low-intensity focused ultrasound for cocaine use disorder: High resolution targeting of the human insula
ABSTRACT Cocaine use disorder (CUD) is a chronic relapsing disorder with significant burden to society costing more than $85 billion per year globally and there is no US Food and D...
C-DIAS RP 2: Implementing contingency management for stimulant use in specialty addiction treatment organizations
C-DIAS RESEARCH PROJECT 2: PROJECT SUMMARY/ABSTRACT This rigorous experiment addresses a critical public health problem--the rising stimulant/opioid epidemic. It advances implement...
Clinical Practice Network
PROJECT SUMMARY/ABSTRACT The purpose of the Clinical Practice Network (CPN) of the MATCHES Telehealth Research Center is to provide the environment for conducting and evaluating th...
Singlet Oxygen-cleavable Prodrugs for Treating Non-Muscle Invasive Bladder Cancers
Bladder cancer (estimated 83,730 new cases and 17,200 death in 2021) is unique in that most (70-80%) of patients are diagnosed with early-stage, non-muscle invasive bladder cancer...
Hardware Acceleration of Functional Languages (HAFLANG)
The performance of programming language implementations until 10-years ago relied on increasing clock frequencies on uni-core CPUs. The last decade has seen the rise of the multi-c...
The Role of Estrogen Receptor Alpha Variant Size and Localization in Modulating TLR7-Induced Inflammation
Systemic lupus erythematosus (SLE) is one of many autoimmune diseases that disproportionately affects females. Although many risk factors for lupus are identified: >170 genes in...
The Role of Estrogen Receptor Alpha Variant Size and Localization in Modulating TLR7-Induced Inflammation
Systemic lupus erythematosus (SLE) is one of many autoimmune diseases that disproportionately affects females. Although many risk factors for lupus are identified: >170 genes in...
Development of a Minimally Invasive Partial Circulatory Support Device for Chronic Use
PROJECT SUMMARY The Nautilus pump is a centrifugal, totally implantable, compact, long-lasting partial circulatory assist device implanted via a minimally invasive pacemaker pocket...
ERI: Resource-Aware Single-Photon Image Sensors
This award is funded in whole or in part under the American Rescue Plan Act of 2021 (Public Law 117-2).Light is composed of discrete energy packets called photons. A camera capture...
Rapid response to pandemic influenza via multi-antigen RNA-based vaccine
Project Summary The proposal is to develop an RNA-based, rapid-response influenza vaccine prototype, supporting NIAID’s call for nucleic acid-based vaccines that protect against pa...
Context-Aware Mobile Intervention for Social Recovery in Serious Mental Illness
PROJECT SUMMARY/ABSTRACT This experimental therapeutics R61/R33 proposal responds to RFA-MH-18-704. The goal of this project is to evaluate a new technology-supported blended inter...
ARM@DA: A Realist Inquiry into Maternity Care @ a DistAnce
BACKGROUNDThe Maternity Transformation Programme in England aims to create safer, kinder, more personalised and family friendly care. A core work stream is ‘harnessing digital tech...
The Role of Estrogen Receptor Alpha Variant Size and Localization in Modulating TLR7-Induced Inflammation
Systemic lupus erythematosus (SLE) is one of many autoimmune diseases that disproportionately affects females. Although many risk factors for lupus are identified: >170 genes in...
Ordinary Citizenship
We often ask what makes a good citizen, but we rarely ask what makes an ordinary citizen. The ordinary citizens are the 'not-so-good' citizens, citizens for whom politics...
LentiTag: A novel approach to the efficient manufacturing of active lentiviral vectors
PROJECT SUMMARY Cell and gene therapies are garnering attention for their remarkable clinical outcomes and their promise to treat diseases previously considered uncurable. Lentivir...
UK-South Korea Prosody Research Network
We will set up a new international Prosody Research Network, with the founding core members based in the UK and South Korea. Prosody refers to the musical aspects of speech, such a...
Identification of Cyclic Peptide Antagonists of an Anti-Opioid G Protein-Coupled Receptor
Identification of Cyclic Peptide Antagonists of an Anti-Opioid G Protein-Coupled Receptor RFA-DA-19-019 R43 Phase I SBIR PI: Sid A. labed Project Summary The highly addictive prope...
Andor Dragonfly 201 Spinning Disk Confocal Microscope System
Project Summary/Abstract: The purpose of this Basic Instrumentation Grant proposal is to request funds to purchase the Andor Dragonfly 201 Spinning Disk Confocal Microscope System...