Results for Technology
53,864 grants found
Showing 48,841 – 48,860 of 53,864 grants for "Technology"
Breath aerosol capture by electric field concentration
Project Summary This proposed project is aimed at developing a method for capturing and concentrating exhaled breath aerosols by electrostatically charging them and collecting them...
Defining multifunctional roles for proteins in development and disease
Project Summary This proposal for the NIGMS R35 Early-Stage Investigator award seeks to support my laboratory’s overall mission of determining multifunctional roles for proteins in...
Defining Sjögren’s pathogenesis by endotype: maladaptive responses of endogenous salivary gland mesenchymal stromal cells
Sjögren's disease (SjD), a common systemic autoimmune disease characterized by severe oral and ocular dryness and multi-organ involvement, has no disease modifying treatment a...
Wirelessly Actuated Ciliary Stent for Minimally Invasive Treatment of Cilia Dysfunction
Project Summary The objective of this proposal is to create a novel ciliary stent integrated with wirelessly actuated artificial cilia for treating cilia dysfunction in various dis...
Acquisition of a Leica high pressure freezer for the cryo-based electron microscopy techniques
PROJECT SUMMARY / ABSTRACT Funds are requested to purchase a Leica EM ICE high-pressure freezer to prepare electron microscopy samples for projects focused around mental health res...
ETSTE DCL: Expanding Low-Income Student Access and Success through an Engineering and Computer Science Student Design Center
This project will contribute to the national need for well-educated scientists, mathematicians, engineers, and technicians by supporting the retention and graduation of high-achiev...
MRI Track 1: Acquisition of a Multi-Collector Inductively Coupled Plasma Mass Spectrometer at the University of Utah
This award funds the purchase of a multi-collector inductively coupled plasma mass spectrometer (MC-ICP-MS) at the University of Utah to enable high-precision non-traditional isoto...
Collaborative Research: An Integrated Experimental and Computational Approach to Reveal Adsorption-Catalysis Cathode Design Principles for Na-S Batteries
Rechargeable batteries are essential for diminishing reliance on fossil fuels, mitigating greenhouse gas emissions, and achieving a net-zero carbon economy. This project aims to en...
Targeting BCMA+ Cells with RNA-engineered CAR T cells to treat Lupus: A Phase 2 clinical study
Systemic lupus erythematosus (SLE) is an autoimmune disease that impacts over 3 million people, causing joint pain, organ damage, and impaired quality of life. Existing SLE drugs a...
Denosumab and sequential zoledronic acid to prevent bone loss and maintain bone mass after spinal cord injury
The current R34 proposal in response to NIAMS PAR-22-205 will provide us the time and resources to complete the detailed clinical trial planning necessary to meet NIAMS and NIH sta...
Flow cytometer for analysis of immune and other cell types
Project Summary/Abstract Researchers at the University of Puerto Rico Medical Sciences Campus (UPR MSC) are proposing to purchase a BD FACSymphony A1TM flow cytometer with 4 lasers...
Uncovering the molecular underpinnings of C15, a potent orthopoxvirus virulence factor
PROJECT SUMMARY The orthopoxvirus (OPXV) genus is home to many severe mammalian pathogens, including variola (VARV) and Mpox (MPXV). Though VARV was eradicated in 1980, OPXVs remai...
Harnessing Machine Learning & Object Detection for Automated Evaluation of Student-folded Protein Models
Project Summary Harnessing Machine Learning & Object Detection for Automated Evaluation of Student-folded Protein Models This project will impact public health through improved...
A Phase 1 Study of Patient-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-601) Administered to Patients with Relapsed Non-Hodgkin Lymphoma
ABSTRACT This application presents MT-601, a novel multi-tumor associated antigen (mTAA)-specific T cell product for the treatment of Non-Hodgkin’s Lymphoma (NHL). NHL is the most...
Development of an In-Home Sensory Training Therapy to Mitigate Falls Risk Among the Elderly
Falls are a major cause of death and morbidity for older adults in the US each year, and injuries from falls leave many older adults with a greater risk of physical and cognitive d...
Role of Cytoskeletal Motor Proteins in Subcellular RNA Localization
ABSTRACT Cells are exquisitely-organized entities, with the location of biomolecules within intimately tied to the maintenance of the organism and the regulation of its genes. Wher...
The Lipofibroblast to Myofibroblast Transition in Systemic Sclerosis
PROJECT SUMMARY/ABSTRACT Systemic sclerosis (SSc) is a rare autoimmune fibrosing disease that affects 24.4/100,000 people in the United States. While rare, SSc has the highest mort...
Alternative splicing in the mouse inner ear at single cell resolution
Sensorineural hearing loss and vestibular dysfunction are common sensory disorders affecting millions of individuals worldwide¹,². The primary cause of both hearing loss and periph...
Modular Toolbox of Protein and Lipid Hybrid Biomaterials for siRNA Delivery
ABSTRACT/PROJECT DESCRIPTION: Technologies for gene delivery are desperately needed to address a wide array of pathological processes in the various tissues of the body. In particu...
Long-term Effects of Educational Investments on Cognitive Health
Project Summary One of the most robust findings in dementia research is that high educational attainment lowers the risk of Alzheimer's disease and related dementia (ADRD); a...