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199,248 grants found
Showing 4,461 – 4,480 of 199,248 grants
Using senolytic agents to suppress the toxicity of chemotherapy
Many of the clinically used cancer chemotherapies have considerable short-term side effects, including fatigue, bone marrow suppression, nausea, diarrhea, and hair loss. Long-term...
Were They Modern Humans? The Problem of the Initial Upper Palaeolithic in West Central Asia
The Initial Upper Palaeolithic (IUP) is a term describing lithic assemblages dated roughly to 50–40 kya in the Near East, Central Europe and North-Eastern Asia, which show traits o...
The rise and fall of Maltese terraced landscapes
Human-modified landscapes modulate the effects of climate change on human societies. For example, concrete surfaces increase flood risks and dense cities exacerbate the effects of...
Identification of persistent neurological complications after eclampsia and discovery of novel neuroprotective treatments to improve maternal outcomes
The goal of this project is to define neurological outcomes after eclampsia and to determine underlying pathophysiological pathways to eclampsia which will lead to new drugs for ne...
Language Processing in Blind Early Visual Cortex? Understanding Limits of Functional Plasticity in Human Brain
What makes the cognitive functions to always fall in the same brain niches, in people all around the world? This consistency might be driven by shared experience, characteristic of...
measuriNg nEURal dynamics with label-free OpticaL multI-DomAin Recordings
The growing societal burden of brain diseases is one of the most significant health challenges globally.To help diagnose or treat these pathologies, there is widespread agreement t...
Governance by data infrastructure in the post-pandemic democracy
Facial recognition cameras, digital identity systems, and health dashboards have become a staple of daily life.By generating data aimed at monitoring or decision-making, these “reg...
The politics of alter-biotic innovation: Examining the making of alternative regimes of biomedical innovation in response to the global health crisis of antimicrobial resistance
Modern antibiotics greatly contributed to fighting infectious diseases.However, today we face a resurgence of deadly drug-resistant microbes due the excessive use of antibiotics –...
SHADES of Bullying: Studying Heterogeneity and Adjustment in Different Environments
SHADES holds great potential for scientific breakthroughs in unravelling the complexities of school bullying by advancing the understanding of heterogeneous youth who bully their p...
Pulsar timing array Inference of the Nanohertz Gravitational wave Universe
We are on the verge of the next big breakthrough in gravitational wave (GW) astronomy: namely the detection of a nano-Hz GW signal with Pulsar Timing Arrays (PTAs).Within the next...
A Fermionic Orbital Quantum Simulator with Local Digital Tunnelling Gates
Fermions are ubiquitous in nature, and the study of fermionic systems with strong correlations lies at the centre of many fundamental and relevant problems in modern physics and ch...
Wildfires and Climate Change: Physics-Based Modelling of Fire Spread in a Changing World
Fire has long been a ubiquitous and essential part of the global environment, as many ecosystems and societal life fundamentally depend on fire.Despite this, we still lack a fundam...
Ancient Virus-like Transposons: from Horizontal Gene Transfer to the Evolution of Novelty
From antiparasitic toxins in butterflies to antifreeze proteins in fish, horizontal gene transfer (HGT)—the non-sexual exchange of genes between species—has been observed in all ma...
Understanding Diagnosing and Early intervention in the Myeloid malignancy Continuum
As humans age, Hematopoietic Stem and Progenitor Cells (HSPCs) accumulate preleukemic mutations (pLMs), forming preleukemic HSPCs (preL-HSPCs) and leading to clonal hematopoiesis (...
MiniTweezer: Optical Tweezers with Automation and Artificial Intelligence
Optical tweezers have revolutionized various scientific disciplines, especially single-molecule research and single-cell mechanobiology.For example, they have played a fundamental...
Plasma Accelerator systems for Compact Research Infrastructures
Plasma accelerators driven by advanced laser sources and/or compact electron linacs are key components for the next generation of green and sustainable research infrastructures.We...
mega-thRust Earthquake SystEm Theory
Plate tectonics and mantle convection drive motions and slip buildup along plate boundaries. The locations where slip will be released during earthquakes are inferred from satellit...
Collaborative Research: REU Site: Earth and Planetary Science and Astrophysics REU at the American Museum of Natural History in Collaboration with the City University of New York
This award provides renewed funding for undergraduate students to conduct experimental, observational, theoretical, and computational research activities in earth science, planetar...
BRC-BIO: Building a Cell - Coupling Amphiphile Prebiotic Chemistry to Protocell Heredity
A fundamental trait of cells is the fact they are encapsulated by a membrane, whose assembly was most likely one of the early steps during life’s emergence on the early Earth. Memb...
I-Corps: Translation Potential of a Robot-enabled Enhancement of Resource-use Efficiency in Row-crop Agriculture
This I-Corps project is focused on the development of small robots suited to navigate commercial row-crops in-season and autonomously, enabling them to produce higher yields with f...