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Actuation spectroscopy as a new label-free tool to study protein properties in real time
Proteins carry out all functions in living cells, from division, metabolism and transport to programmed cell death. Understanding how protein structure and movements relate to thei...
Light Emitting Silicon Germanium
Our vision is to revolutionize information and quantum technologies by blending photonic and electronic functionality onto a single chip. This long-standing challenge has remained...
Hormone-Induced Resistance to GLP-1 Receptor Agonists in Diabetes: Unraveling the Molecular Complexities
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have revolutionized the treatment of type 2 diabetes mellitus (T2DM). However, a subset of patients does not respond to these a...
Bis(carbene) Analogues of Aluminium and Gallium as Building Blocks for Highly Selective Reagents and Next Generation Catalysts
Molecular chemistry impacts on a wide range of transformational activities that the society relies on and thus plays a key role in addressing the societal challenges facing the Eur...
Broad-spectrum Antiviral siRNAs: Influenza Strains Targeted by Anticipation
Fighting emerging viruses has been a major challenge in the development of novel therapeutics. With the current global changes and massive modification of the biosphere, the issue...
Artificial molecular machines in membranes: transmembrane relays for ion transport, catalysis and cargo pumping
This program will develop artificial molecular machines confined within lipid bilayer membranes, to control transmembrane transport and catalysis in cellular systems. Molecular mac...
Understanding the Role of Economic Imagination for Advancing Decarbonization in Europe
How do we imagine the decarbonized economy of the future? While research suggests that opposition to climate mitigation is often driven by economic concerns, we have little systema...
Meteotsunami detection and tracking: Developing a solution based on assessment of real-time measurements
Meteorological tsunamis (meteotsunamis) are long ocean waves (periods of: 1 < T < ~120 min) that have the same periods, wavelengths and amplitudes as seismic tsunamis, but are gene...
Promiscuous Print: Legal Deposit Libraries, Rejected Texts, and New Methods for Negative Bibliography
PROMPRINT will uncover and analyze the rejects of legal deposit: the printed texts excluded from the ostensibly universal archive promised by copyright libraries. Legal deposit wor...
Dynamic Megabar Chemistry
Pressures above 1 Mbar, equivalent to energy densities stored in chemical bonds, are predicted to severely reshape the periodic table of the elements as we know it. Such extreme co...
Ring laser gyroscopes for ground motion sensing
Sensors for rotation are ubiquitous in our daily life, ranging from consumer electronics to navigation systems. Applications that require highest sensitivity for very small rotatio...
Automated High-throughput Behavioral Measurement in Co-Housed Mice for Safer and More Effective Psychiatric Drug Development
Drug development for psychiatric and neurological disorders requires extensive preclinical testing for validation of safety and efficacy. Preclinical investigation of Central Nervo...
Handshake Complexes of Chiral Nanoparticles and Proteins
Chirality, or the absence of mirror symmetry, is omnipresent in both biological and abiological forms of matter. Rapid progress has recently been achieved in the synthesis of chira...
Unraveling the Mysteries of Vibrational Strong Coupling
Polaritonic Chemistry is a new and exciting field that has emerged from the fusion of chemistry and cavity quantum electrodynamics. In this innovative realm, and specifically under...
Natural Auditory SCEnes in Humans and Machines: Establishing the Neural Computations of Everyday Hearing
In an office, on a metro, or at home, diverse sounds may be surrounding you: a computer fan, footsteps and indistinct chatter, distant cars, the train slowing down. These sounds sh...
A theory and model of the neural transformations mediating human object perception
In the blink of an eye our brain rapIn the blink of an eye our brain rapidly transforms the photons hitting our retina into a rich and detailed percept of the world as consisting o...
Postdoctoral Fellowship: PRFB: Understanding the past to conserve the future: integrating historical museum collections and avian conservation genomics
This action funds an NSF Postdoctoral Research Fellowship in Biology for FY 2024, Broadening Participation of Groups Underrepresented in Biology. The Fellowship supports a research...
Postdoctoral Fellowship: PRFB: Evaluating the Role of Transcriptional Plasticity in Insect Host Specialization
This action funds an NSF Postdoctoral Research Fellowship in Biology for FY 2024, Integrative Research Investigating the Rules of Life Governing Interactions Between Genomes, Envir...
Postdoctoral Fellowship: PRFB: Characterizing the history of Batrachochytrium dendrobatidis, a globally-significant amphibian pathogen, with historic and sedimentary DNA
This action funds an NSF Postdoctoral Research Fellowship in Biology for FY 2024, Integrative Research Investigating the Rules of Life Governing Interactions Between Genomes, Envir...
Enhancement of Memory- and Energy-related Properties of Fluorite Structured Ferroelectrics
For several decades, ferroelectric (FE) materials (particularly lead-based perovskite materials) attained wide attention for memory (non-volatile) and energy storage applications....