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199,248 grants found
Showing 3,761 – 3,780 of 199,248 grants
Omeprazole for Treatment of Term and preterm infants with gastro-oEsophageal Reflux (OTTER)
Research question: In preterm (<37 weeks gestation) and term-born (=37 weeks gestation) infants under 6 months of age clinically diagnosed with gastro-oesophageal reflux (Populatio...
Developing and applying new autistic-led standards for social care environments: a participatory action research study of Ethical Quality Autistic-Led Support (EQUALS)
Numerous reviews have highlighted that residential social care and supported living services are currently failing autistic adults. Best practice standards often remain unmet, plac...
Dissecting long non-coding RNA function using in vivo synthetic biology
Precise spatiotemporal regulation of gene expression is essential for healthy embryonic development. Long non-coding RNAs (lncRNAs) contribute to the regulation of gene expression....
Atomically Precise Control of Strong Coupling In Molecular Dimers (SCIMER)
SCIMER aims to demonstrate strong dipole-dipole coupling of molecular dimers with a long-term goal of establishing rationally synthesized molecules as a reliable resource for quant...
CAREER: Evolutionary dynamics of polycistronic gene expression in Archaeplastida: implications for stress adaptation and evolution
In prokaryotes, the expression of clusters of genes, typically functionally related, often is controlled by a single regulatory sequence leading to a single transcript molecule tha...
ANXIOMICS: Finding the mind, brain and immune pathways to anxiety
We do not know why some people experience anxiety disorders, but with twin heritability estimates of 20 – 60%, our genes play a key causal role. However, the mechanisms through whi...
Exploring the contribution of social inequality to the evolution of the Mycobacterium tuberculosis complex across five millennia
Tuberculosis (TB) is globally the top cause of death by an infectious agent but disproportionately affects those in poor countries without access to adequate nutrition. TB is today...
BiBBS ACHIEVE: Addressing Childhood Inequalities through Evidence-Based Early Interventions using Born in Bradford’s Better Start (BiBBS) birth cohort
Our vision is to conduct discovery research to better understand how to effectively intervene to create a healthier, happier, and fairer future for socially disadvantaged children....
Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR): a Pilot Study
Rheumatoid arthritis (RA) is an autoimmune condition leading to inflammation and pain. Even after treating inflammation, RA patients experience persistent residual pain similar to...
Exploring the development of and public support for healthy and planet- friendly food marketing policies: co-designing meat marketing restrictions
Current patterns in the production and consumption of food are resulting in poor health and environmental outcomes. Since marketing influences food choices, using policies to chang...
SISTAH: Understanding and Enhancing Cancer Health Equity for Black and Mixed Black ethnic minority Women through a community participatory-based approach (CBPR) and Sistah Circles/Sister Circles.
Black and mixed Black ethnic minority women in the UK are more likely to be diagnosed with breast, ovarian, and uterine cancers at later stages, when treatment is less likely to be...
Spatial Prostate Assessment and the Circulating Environment - discovering the lethal clone (SPACE-X)
Background Prostate cancer (PCa) diagnosis has advanced significantly, but we still lack certainty about who needs treatment. PCa is inherently heterogeneous, as demonstrated by my...
Understanding the pathophysiology of auto-immunity through Immune Checkpoint Blockade
Cancer immunotherapy consisting of Immune Checkpoint Blockade (ICB) has reshaped management and outcomes for many cancers, but frequently elicits autoimmune side-effects (immune-re...
Discovering and targeting the wider super-enhancer network of acute lymphoblastic leukaemia
Background B cell acute lymphoblastic leukaemia (B-ALL) is the most common childhood malignancy and despite survival being high (children, ~90%), outcome is worse for adults and th...
Understanding tumour progression using different tumour-specific factors
Background Cancer early detection presents the challenge of balancing the interception of progressive lesions before they become invasive with avoiding overdiagnosis of indolent le...
Identifying, understanding and addressing inequalities in cancer treatment
Background. Cancer is a leading cause of mortality in the United Kingdom. Chances for survival are improved when patients receive treatment (‘treatment receipt’), with further impr...
Intra- and interspecific variation of avian demographic histories in the past million years
macroecology
The Churches of Rome in the Middle Ages 1050–1300. Liturgical Furnishing and Architecture (Corpus Cosmatorum II), vol. 7: Churches P–Z and Corpus Cosmatorum III
Spolia
FLARE - ATLAS Detector Operation, Phase-II and Phase-III Upgrade at the CERN Large Hadron Collider (LHC)
Trigger
SwarmOps: Human-sensing based MLOps for Collaborative Cyber-physical systems
Machine Learning, Search-based algorithms