Results for Environment
40,772 grants found
Showing 37,561 – 37,580 of 40,772 grants for "Environment"
South Texas Alzheimer’s Disease Center Outreach, Recruitment and Engagement Core
Summary Outreach, Recruitment and engagement (OREC) In 2050, Hispanic adults over age 65 are expected to account for 20% of the population, up from 7% in 20101. However, they remai...
South Texas Alzheimer's Disease Center Clinical Core
Abstract The Mexican-American (MA) Hispanic community is the most rapidly growing minority and is disproportionately affected by Alzheimer’s disease and related dementias (ADRDs)....
MANATEE-T1D: Metformin ANd AutomaTEd insulin delivery system Effects on renal vascular resistance, insulin sensitivity, and cardiometabolic function in youth with Type 1 Diabetes
PROJECT SUMMARY/ABSTRACT: Diabetic kidney disease (DKD) and cardiovascular disease (CVD) remain the leading causes of morbidity and mortality in people with type 1 diabetes (T1D) a...
Bioactive lipid mediated Endothelial niche regulation of alveolar epithelial repair
Abstract The lung alveolar epithelium is exposed to the environment and pathogens and is thus highly susceptible to injury. Repair of the alveolar epithelium requires the activatio...
The role of enteroendocrine cell differentiation in the success of bariatric surgery
Project Abstract: One of the most prominent reasons to study the mechanisms underlying the success of bariatric surgery is to replicate surgery outcomes with non-invasive treatment...
Defining the antigenic determinants of the adaptive immune response in IgG4-related disease
This mentored research program aims to develop Dr. Perugino into an independent investigator studying the immunologic mechanisms of fibrosis. The research goals entail the identifi...
SWI/SNF chromatin remodelers in tumor-associated antigen-specific CD8+ cytotoxic T cells
Project Summary/Abstract: Transcriptional and chromatin dysregulation are hallmarks of cancer. In this project, we functionally characterize alterations in the pioneer transcriptio...
Arsenic and other co-metals in the San Carlos Apache drinking water
ABSTRACT. The broad, long-term objectives of this K01 project are to improve the health of Apache American Indians through a study that examines the association between cancer (CA)...
NSF Center for the Chemistry of Molecularly Optimized Networks
The NSF Center for the Chemistry of Molecularly Optimized Networks (MONET) strives to create the fundamental knowledge and uncover generalizable design principles that connect the...
CAREER: Diversity in the darkness: Integrating environmental genetics, comparative genomics, and citizen science to shed light on groundwater biodiversity
Many organisms are found in subterranean water (groundwater), yet the diversity and relationships of these organisms are poorly known, in part because caves and other subterranean...
Targeted delivery of a proangiogenic and promyogenic protein for regeneration of diabetic ischemic limbs
Program Director/Principal Investigator (Last, First, Middle): GUAN, JIANJUN Project Summary Diabetic patients with critical limb ischemia (CLI) have significantly high rates of li...
Targeted delivery of a proangiogenic and promyogenic protein for regeneration of diabetic ischemic limbs
Program Director/Principal Investigator (Last, First, Middle): GUAN, JIANJUN Project Summary Diabetic patients with critical limb ischemia (CLI) have significantly high rates of li...
Targeted delivery of a proangiogenic and promyogenic protein for regeneration of diabetic ischemic limbs
Program Director/Principal Investigator (Last, First, Middle): GUAN, JIANJUN Project Summary Diabetic patients with critical limb ischemia (CLI) have significantly high rates of li...
Pd-Catalyzed C(sp3)-H Functionalizations Directed by Free Alcohols and Boc-Protected Amines
PROJECT SUMMARY/ABSTRACT Subtle structural modifications have the potential to dramatically alter the biological activity of small molecules. Consequently, the development of synth...
Spermatogonial stem cell regulation and maintenance of male fertility
Project Summary Infertility affects 15% of couples and in about half of these cases the male partner contributes to the failure to conceive. One cause of male infertility is an ina...
Clinical Core
ABSTRACT – JHU TRAC CLINICAL CORE (CC) Tuberculosis (TB) remains a major global health problem and transformative clinical and translational science research is needed to meaningfu...
Clinical Core
ABSTRACT – JHU TRAC CLINICAL CORE (CC) Tuberculosis (TB) remains a major global health problem and transformative clinical and translational science research is needed to meaningfu...
Clinical Core
ABSTRACT – JHU TRAC CLINICAL CORE (CC) Tuberculosis (TB) remains a major global health problem and transformative clinical and translational science research is needed to meaningfu...
Autonomous Modelling Solutions for Operational Structural Dynamic Systems
Identifying and understanding how engineering structures respond over time to different loads is a key task which supports many other activities. For example, the creation of digit...
The neural circuitry of sensory-evoked awakenings during sleep and anaesthesia
Sleep, wakefulness, and anaesthesia are behavioural states with characteristic differences in brain activity that dramatically affects our sensory perception and behavioural respon...